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Salutaridine

PubChem CID: 5408233

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Compound Synonyms Salutaridine, Sinoacutine, 1936-18-1, (+)-salutaridine, Floripavine, UNII-7X10PRH74D, SALUTARIDIN, 7X10PRH74D, CHEBI:17225, SALUTARIDINE [MI], SALUTARIDINE, (+)-, HSDB 8325, DTXSID60941041, (-)-Sinoacutine, 4-Hydroxy-3,6-dimethoxy-17-methyl-5,6,8,14-tetradehydromorphinan-7-one, Morphinan-7-one, 5,6,8,14-tetradehydro-4-hydroxy-3,6-dimethoxy-17-methyl-, (1S,9R)-3-hydroxy-4,13-dimethoxy-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5,10,13-pentaen-12-one, 5,6,8,14-Tetradehydro-4-hydroxy-3,6-dimethoxy-17-methyl-morphinan-7-one, (1S,9R)-3-hydroxy-4,13-dimethoxy-17-methyl-17-azatetracyclo(7.5.3.01,10.02,7)heptadeca-2(7),3,5,10,13-pentaen-12-one, Floripavine, (+)-Salutaridine, Salutaridin, 5,6,8,14-Tetradehydro-4-hydroxy-3,6-dimethoxy-17-methylmorphinan-7-one, SCHEMBL563455, CHEMBL404097, GVTRUVGBZQJVTF-YJYMSZOUSA-N, DTXCID501369490, BDBM50378615, 5,6,8,14-Tetradehydro-4-hydroxy-3,6-dimethoxy-17-methylmorphinan-7-one, AKOS040753908, NS00094132, C05179, Q7406319
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 59.0
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CCC23CCCC(CC4CCCCC42)C3C1
Np Classifier Class Isoquinoline alkaloids, Morphinan alkaloids
Deep Smiles COC=C[C@@]CCN[C@@H]C6=CC%10=O))))Ccc8cO)ccc6))OC))))))))C
Heavy Atom Count 24.0
Classyfire Class Phenanthrenes and derivatives
Scaffold Graph Node Level OC1CCC23CCNC(CC4CCCCC42)C3C1
Isotope Atom Count 0.0
Molecular Complexity 612.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 2.0
Uniprot Id P35372, P24941
Iupac Name (1S,9R)-3-hydroxy-4,13-dimethoxy-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5,10,13-pentaen-12-one
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Benzenoids
Target Id NPT145
Xlogp 1.9
Gsk 4 400 Rule True
Molecular Formula C19H21NO4
Scaffold Graph Node Bond Level O=C1C=CC23CCNC(Cc4ccccc42)C3=C1
Prediction Swissadme 1.0
Inchi Key GVTRUVGBZQJVTF-YJYMSZOUSA-N
Silicos It Class Soluble
Fcsp3 0.4210526315789473
Logs -2.271
Rotatable Bond Count 2.0
Logd 1.066
Synonyms salutaridine
Esol Class Soluble
Functional Groups CN(C)C, COC1=CCC(C)=CC1=O, cO, cOC
Compound Name Salutaridine
Prediction Hob Swissadme 1.0
Exact Mass 327.147
Formal Charge 0.0
Monoisotopic Mass 327.147
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 327.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 2.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -3.151256
Inchi InChI=1S/C19H21NO4/c1-20-7-6-19-10-16(24-3)14(21)9-12(19)13(20)8-11-4-5-15(23-2)18(22)17(11)19/h4-5,9-10,13,22H,6-8H2,1-3H3/t13-,19+/m1/s1
Smiles CN1CC[C@]23C=C(C(=O)C=C2[C@H]1CC4=C3C(=C(C=C4)OC)O)OC
Nring 4.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Aloe Microstigma (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Armoracia Rusticana (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Brassica Juncea (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Capsella Bursa-Pastoris (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Chrozophora Prostrata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Isatis Tinctoria (Plant) Rel Props:Source_db:cmaup_ingredients
  • 7. Outgoing r'ship FOUND_IN to/from Papaver Bracteatum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 8. Outgoing r'ship FOUND_IN to/from Papaver Orientale (Plant) Rel Props:Reference:ISBN:9788185042053
  • 9. Outgoing r'ship FOUND_IN to/from Papaver Somniferum (Plant) Rel Props:Source_db:npass_chem_all
  • 10. Outgoing r'ship FOUND_IN to/from Patrinia Villosa (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 11. Outgoing r'ship FOUND_IN to/from Pavonia Odorata (Plant) Rel Props:Reference:ISBN:9788185042053
  • 12. Outgoing r'ship FOUND_IN to/from Sinomenium Acutum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 13. Outgoing r'ship FOUND_IN to/from Stephania Delavayi (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 14. Outgoing r'ship FOUND_IN to/from Thlaspi Arvense (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all