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Vinblastine Sulfate

PubChem CID: 5388983

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Compound Synonyms Vinblastine sulfate, 143-67-9, Velsar, Velban, Velbe, EXAL, Vinblastine (sulfate), Alkaban-aq, VLB monosulfate, 29060-LE, Vinblastine sulphate, NSC-49842, N00W22YO2B, 29060LE, 29060 LE, MLS000863275, Vincaleukoblastine, sulfate (1:1) (salt), Vincaleukoblastine sulfate, NSC 49842, DTXSID601017133, Belvan, VLB, SMR000058844, Vincaleucoblastine sulfate, DSSTox_CID_27831, DSSTox_RID_82594, DSSTox_GSID_47853, vincaleukoblastine,sulfate(1:1), Uniblastin, VINBLASTINE SULFATE (IARC), VINBLASTINE SULFATE [IARC], Rozevin sulfate, VINBLASTINE SULFATE (MART.), VINBLASTINE SULFATE [MART.], VINBLASTINE SULFATE (USP-RS), VINBLASTINE SULFATE [USP-RS], VINBLASTINE SULFATE (EP MONOGRAPH), VINBLASTINE SULFATE [EP MONOGRAPH], VINBLASTINE SULFATE (USP MONOGRAPH), VINBLASTINE SULFATE [USP MONOGRAPH], CAS-18556-44-0, Vincaleukoblastine, sulfate, UNII-N00W22YO2B, NSC49842, CCRIS 2584, Vinblastini sulfas, CHEMBL378544, NCGC00095285-01, Vinblastine sulfate, methyl (3aR,4R,5S,5aR,10bR,13aR)-4-(acetyloxy)-3a-ethyl-9-[(5S,7R,9S)5-ethyl-5-hydroxy-9-(methoxycarbonyl)-1,4,5,6,7,8,9,10-octahydro-2H-3,7-methanoazacycloundecino[5,4-b]indol-9-yl]-5-hydroxy-8-methoxy-6-methyl-3a,4,5,5a,6,11,12,13a-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate sulfate, EINECS 205-606-0, Sulfate, Vinblastine, Vinblastine sulfate [USAN:USP:JAN], Opera_ID_960, AI3-52943, NCGC00181127-01, SCHEMBL3549, MLS000069550, MLS002153253, MLS002207069, DTXCID7027831, VINBLASTINE SULFATE [MI], VINBLASTINE SULFATE [JAN], KDQAABAKXDWYSZ-PNYVAJAMSA-N, Vinblastine (sulfate) (Standard), HMS2235E07, HMS3403N09, VINBLASTINE SULFATE [USAN], VINBLASTINE SULFATE [VANDF], Tox21_111498, Tox21_112735, AC-821, HY-13780R, VINBLASTINE SULFATE [WHO-DD], VINBLASTINE SULFATE [WHO-IP], AKOS015960580, Tox21_111498_1, Tox21_112735_1, CS-1365, NCGC00263548-01, NCGC00344583-01, VINBLASTINE SULFATE [ORANGE BOOK], HY-13780, VINBLASTINI SULFAS [WHO-IP LATIN], NS00076398, EN300-1268144, SR-01000000155, Vinblastine sulfate salt, powder, >=96% (HPLC), SR-01000000155-7, Q27077057, Z3014322079, Vinblastine sulfate, European Pharmacopoeia (EP) Reference Standard, Vinblastine sulfate, United States Pharmacopeia (USP) Reference Standard, 205-606-0, methyl (1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-12-ethyl-4-[(13S,15R,17S)-17-ethyl-17-hydroxy-13-(methoxycarbonyl)-1,11-diazatetracyclo[13.3.1.0?,??.0?,??]nonadeca-4(12),5(10),6,8-tetraen-13-yl]-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.0?,?.0?,?.0??,??]nonadeca-2(7),3,5,13-tetraene-10-carboxylate, sulfuric acid, methyl (1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-12-ethyl-4-[(13S,15R,17S)-17-ethyl-17-hydroxy-13-(methoxycarbonyl)-1,11-diazatetracyclo[13.3.1.0^{4,12}.0^{5,10}]nonadeca-4(12),5(10),6,8-tetraen-13-yl]-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadeca-2,4,6,13-tetraene-10-carboxylate, sulfuric acid, methyl (1R,9R,10S,11R,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15R,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate, sulfuric acid, Methyl (3aR,4R,5S,5aR,10bR,13aR)-4-acetoxy-3a-ethyl-9-((5S,7R,9S)-5-ethyl-5-hydroxy-9-methoxycarbonyl-1,4,5,6,7,8,9,10-octahydro-3,7-methano-3-azacycloundecino(5,4-b)indol-9-yl)-5-hydroxy-8-methoxy-6-methyl-3a,4,5,5a,6,11,12,13a-octahydro-1H-indolizino(8,1-cd)carbazole-5-carboxylate monosulfate
Topological Polar Surface Area 237.0
Hydrogen Bond Donor Count 5.0
Heavy Atom Count 64.0
Isotope Atom Count 0.0
Molecular Complexity 1780.0
Database Name cmaup_ingredients;pubchem
Defined Atom Stereocenter Count 9.0
Iupac Name methyl (1R,9R,10S,11R,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15R,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate, sulfuric acid
Prediction Hob 0.0
Molecular Formula C46H60N4O13S
Prediction Swissadme 0.0
Inchi Key KDQAABAKXDWYSZ-PNYVAJAMSA-N
Fcsp3 0.5869565217391305
Logs -4.756
Rotatable Bond Count 10.0
Logd 3.044
Compound Name Vinblastine Sulfate
Prediction Hob Swissadme 0.0
Exact Mass 908.388
Formal Charge 0.0
Monoisotopic Mass 908.388
Hydrogen Bond Acceptor Count 16.0
Molecular Weight 909.1
Covalent Unit Count 2.0
Total Atom Stereocenter Count 9.0
Total Bond Stereocenter Count 0.0
Esol -5.128259100000001
Inchi InChI=1S/C46H58N4O9.H2O4S/c1-8-42(54)23-28-24-45(40(52)57-6,36-30(15-19-49(25-28)26-42)29-13-10-11-14-33(29)47-36)32-21-31-34(22-35(32)56-5)48(4)38-44(31)17-20-50-18-12-16-43(9-2,37(44)50)39(59-27(3)51)46(38,55)41(53)58-7, 1-5(2,3)4/h10-14,16,21-22,28,37-39,47,54-55H,8-9,15,17-20,23-26H2,1-7H3, (H2,1,2,3,4)/t28-,37-,38+,39+,42-,43+,44+,45-,46-, /m0./s1
Smiles CC[C@@]1(C[C@H]2C[C@@](C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)[C@]78CCN9[C@H]7[C@@](C=CC9)([C@H]([C@@]([C@@H]8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O.OS(=O)(=O)O
Nring 9.0
Defined Bond Stereocenter Count 0.0

  • 1. Outgoing r'ship FOUND_IN to/from Scoparia Dulcis (Plant) Rel Props:Source_db:cmaup_ingredients