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Hydroxywighteone

PubChem CID: 5378945

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Compound Synonyms Hydroxywighteone, Glabrisoflavone, 5,7,4'-Trihydroxy-6-(3-hydroxymethyl-2-butenyl)isoflavone, 5,7-dihydroxy-6-[(E)-4-hydroxy-3-methylbut-2-enyl]-3-(4-hydroxyphenyl)chromen-4-one, 5,7,4'-Trihydroxy-6-[3-(hydroxymethyl)but-2-enyl]isoflavone, 5,7-Dihydroxy-6-[4-hydroxy-3-methyl-2-butenyl]-3-(4-hydroxyphenyl)-4H-chromen-4-one, 5,7,4'-Trihydroxy-6-(3-(hydroxymethyl)but-2-enyl)isoflavone, 5,7-dihydroxy-6-((E)-4-hydroxy-3-methylbut-2-enyl)-3-(4-hydroxyphenyl)chromen-4-one, 5,7-Dihydroxy-6-(4-hydroxy-3-methyl-2-butenyl)-3-(4-hydroxyphenyl)-4H-chromen-4-one, CHEMBL1086439, LMPK12050195, (e)-5,7,4'-trihydroxy-6-(3-hydroxymethyl-2-butenyl)isoflavone, 104691-87-4
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 107.0
Hydrogen Bond Donor Count 4.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1C2CCCCC2CCC1C1CCCCC1
Np Classifier Class Isoflavones
Deep Smiles OC/C=C/CccO)cccc6O))c=O)cco6))cccccc6))O))))))))))))))/C
Heavy Atom Count 26.0
Classyfire Class Isoflavonoids
Scaffold Graph Node Level OC1C(C2CCCCC2)COC2CCCCC21
Classyfire Subclass Isoflavans
Isotope Atom Count 0.0
Molecular Complexity 575.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name 5,7-dihydroxy-6-[(E)-4-hydroxy-3-methylbut-2-enyl]-3-(4-hydroxyphenyl)chromen-4-one
Veber Rule True
Classyfire Superclass Phenylpropanoids and polyketides
Xlogp 3.3
Gsk 4 400 Rule True
Molecular Formula C20H18O6
Scaffold Graph Node Bond Level O=c1c(-c2ccccc2)coc2ccccc12
Inchi Key AROTXIUFXQZGLT-BIIKFXOESA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 4.0
Synonyms (e)-5,7,4'-trihydroxy-6-(3-hydroxymethyl-)-2-buten isoflavone(glabrisoflavone, (e)-5,7,4'-trihydroxy-6-(3-hydroxymethyl-2-butenyl)isoflavone (glabrisoflavone), glabrisoflavone
Esol Class Moderately soluble
Functional Groups C/C=C(/C)C, CO, c=O, cO, coc
Compound Name Hydroxywighteone
Exact Mass 354.11
Formal Charge 0.0
Monoisotopic Mass 354.11
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 354.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 1.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C20H18O6/c1-11(9-21)2-7-14-16(23)8-17-18(19(14)24)20(25)15(10-26-17)12-3-5-13(22)6-4-12/h2-6,8,10,21-24H,7,9H2,1H3/b11-2+
Smiles C/C(=C\CC1=C(C2=C(C=C1O)OC=C(C2=O)C3=CC=C(C=C3)O)O)/CO
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 1.0
Egan Rule True
Np Classifier Superclass Isoflavonoids

  • 1. Outgoing r'ship FOUND_IN to/from Glycyrrhiza Glabra (Plant) Rel Props:Reference:https://www.ncbi.nlm.nih.gov/pubmed/11696898