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Isositskiakine isomer K060

PubChem CID: 5377267

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Compound Synonyms Isositskiakine isomer K060, methyl 2-[(3Z)-3-ethylidene-2,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl]-3-hydroxypropanoate, 6519-27-3, 17, 19,20-didehydro-17-hydroxy-, methyl ester, 17, 19,20-didehydro-17-hydroxy-, methyl ester, (16S,19E)-, Corynan-17-oic acid,20-didehydro-16-(hydroxymethyl)-, methyl ester, NSC-338932, Corynan-16-carboxylic acid,20-didehydro-17-hydroxy-, methyl ester, (16R,19E)-, (16s,19Z)-Isositsirikine, RGXKJLTVROJBKZ-QLKAYGNNSA-N, NSC282700, NSC338932, NSC-282700
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 65.6
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CCC2C(CCC3C4CCCCC4CC23)C1
Np Classifier Class Corynanthe type
Deep Smiles COC=O)CCCCNC/C/6=CC))))CCcc6[nH]cc5cccc6)))))))))))))))CO
Heavy Atom Count 26.0
Classyfire Class Corynanthean-type alkaloids
Scaffold Graph Node Level CC1CCC2C3NC4CCCCC4C3CCN2C1
Isotope Atom Count 0.0
Molecular Complexity 563.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name methyl 2-[(3Z)-3-ethylidene-2,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl]-3-hydroxypropanoate
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 1.8
Gsk 4 400 Rule True
Molecular Formula C21H26N2O3
Scaffold Graph Node Bond Level C=C1CCC2c3[nH]c4ccccc4c3CCN2C1
Inchi Key RGXKJLTVROJBKZ-QLKAYGNNSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 4.0
Synonyms isositsirikine
Esol Class Soluble
Functional Groups C/C=C(/C)C, CN(C)C, CO, COC(C)=O, c[nH]c
Compound Name Isositskiakine isomer K060
Exact Mass 354.194
Formal Charge 0.0
Monoisotopic Mass 354.194
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 354.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 3.0
Total Bond Stereocenter Count 1.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C21H26N2O3/c1-3-13-11-23-9-8-15-14-6-4-5-7-18(14)22-20(15)19(23)10-16(13)17(12-24)21(25)26-2/h3-7,16-17,19,22,24H,8-12H2,1-2H3/b13-3+
Smiles C/C=C/1\CN2CCC3=C(C2CC1C(CO)C(=O)OC)NC4=CC=CC=C34
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 1.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Catharanthus Roseus (Plant) Rel Props:Reference:https://doi.org/10.1093/database/bav075
  • 2. Outgoing r'ship FOUND_IN to/from Hunteria Zeylanica (Plant) Rel Props:Reference:ISBN:9788185042114