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1-Hydroxy-10-methylacridone

PubChem CID: 5376484

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Compound Synonyms 16584-54-6, 1-hydroxy-10-methylacridone, 1-hydroxy-N-methylacridone, 1-Hydroxy-10-methylacridin-9(10H)-one, 1-hydroxy-10-methylacridin-9-one, 1-Hydroxy-10-methyl-9(10H)-acridinone, 1-HYDROXY-10-METHYL-10H-ACRIDIN-9-ONE, 1-HYDROXY-10-METHYL-9,10-DIHYDROACRIDIN-9-ONE, 9(10H)-Acridinone, 1-hydroxy-10-methyl-, MFCD01871520, 1-Hydrxy-N-methylacridon, 52B4LWQ6VU, MLS000755253, SCHEMBL9352178, CHEMBL1288799, DTXSID40418786, CHEBI:178584, NHYDBJFGZCQFEO-UHFFFAOYSA-N, REGID_for_CID_5376484, HMS2662F10, HY-N9147, 1-hydroxy-10-methyl-acridin-9-one, 10-Methyl-1-oxidanyl-acridin-9-one, 9-Acridanone, 1-hydroxy-10-methyl-, AKOS015992992, DA-49173, PD095799, RD6-5071, SMR000338128, 1-Hydroxy-10-methyl-10-hydroacridin-9-one, 1-Hydroxy-10-methyl-9(10H)-acridinone #, MLS000755253-02, 5P-071, InChI=1/C14H11NO2/c1-15-10-6-3-2-5-9(10)14(17)13-11(15)7-4-8-12(13)16/h2-8,16H,1H
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 40.5
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1C2CCCCC2CC2CCCCC21
Np Classifier Class Acridone alkaloids
Deep Smiles Cncccccc6c=O)cc%10cccc6O
Heavy Atom Count 17.0
Classyfire Class Quinolines and derivatives
Description Alkaloid from the roots of Ruta graveolens (rue)and is also isolated from the callus cultures obtained from the meristematic cells of Ruta graveolens. 1-Hydroxy-10-methylacridone is found in herbs and spices.
Scaffold Graph Node Level OC1C2CCCCC2NC2CCCCC21
Classyfire Subclass Benzoquinolines
Isotope Atom Count 0.0
Molecular Complexity 317.0
Database Name cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id P42858, P10636, Q8IUX4, n.a.
Iupac Name 1-hydroxy-10-methylacridin-9-one
Prediction Hob 1.0
Class Quinolines and derivatives
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Target Id NPT1197, NPT51
Xlogp 3.8
Superclass Organoheterocyclic compounds
Subclass Benzoquinolines
Gsk 4 400 Rule True
Molecular Formula C14H11NO2
Scaffold Graph Node Bond Level O=c1c2ccccc2[nH]c2ccccc12
Prediction Swissadme 0.0
Inchi Key NHYDBJFGZCQFEO-UHFFFAOYSA-N
Silicos It Class Moderately soluble
Fcsp3 0.0714285714285714
Logs -3.71
Rotatable Bond Count 0.0
State Solid
Logd 2.415
Synonyms 1-Hydroxy-10-methylacridone, 1-Hydroxy-N-methylacridone, 1-Hydroxy-10-methyl-9,10-dihydroacrid-9-one, 1-hydroxy-10-methyl-acridin-9-(10h)-one, 1-hydroxy-10-methylacridin-9(10h)-one, 1-hydroxy-n-methylacridone
Substituent Name Acridone, Dihydroquinolone, Dihydroquinoline, Benzenoid, Pyridine, Heteroaromatic compound, Vinylogous amide, Vinylogous acid, Azacycle, Hydrocarbon derivative, Organooxygen compound, Organonitrogen compound, Aromatic heteropolycyclic compound
Esol Class Moderately soluble
Functional Groups c=O, cO, cn(c)C
Compound Name 1-Hydroxy-10-methylacridone
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 225.079
Formal Charge 0.0
Monoisotopic Mass 225.079
Hydrogen Bond Acceptor Count 3.0
Molecular Weight 225.24
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aromatic heteropolycyclic compounds
Lipinski Rule Of 5 True
Esol -4.580193564705882
Inchi InChI=1S/C14H11NO2/c1-15-10-6-3-2-5-9(10)14(17)13-11(15)7-4-8-12(13)16/h2-8,16H,1H3
Smiles CN1C2=C(C(=CC=C2)O)C(=O)C3=CC=CC=C31
Nring 3.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Taxonomy Direct Parent Acridones
Np Classifier Superclass Anthranilic acid alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Boenninghausenia Albiflora (Plant) Rel Props:Reference:ISBN:9788185042114
  • 2. Outgoing r'ship FOUND_IN to/from Ruta Chalepensis (Plant) Rel Props:Reference:ISBN:9788172363093
  • 3. Outgoing r'ship FOUND_IN to/from Ruta Graveolens (Plant) Rel Props:Reference:ISBN:9788185042145
  • 4. Outgoing r'ship FOUND_IN to/from Thamnosma Rhodesica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all