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2-Hydroxychalcone

PubChem CID: 5367146

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Compound Synonyms 2-Hydroxychalcone, 644-78-0, 42224-53-3, 3-(2-hydroxyphenyl)-1-phenylprop-2-en-1-one, (E)-3-(2-hydroxyphenyl)-1-phenylprop-2-en-1-one, (2E)-3-(2-hydroxyphenyl)-1-phenylprop-2-en-1-one, (E)-2-Hydroxychalcone, 2-(2-Hydroxybenzal)acetophenone, Salicylalacetophenone, 2-Propen-1-one, 3-(2-hydroxyphenyl)-1-phenyl-, 2-Hydroxybenzylidene acetophenone, EINECS 211-422-1, NSC 640539, AI3-00855, MLS002608038, NSC640539, 3-(2-hydroxyphenyl)-1-phenyl-2-propen-1-one, Chalcone, 1, MFCD00016449, 2-Hydroxychalcone, 95%, SCHEMBL626785, SCHEMBL626787, CHEMBL147067, BDBM86002, HMS3078L22, NSC37432, 2-(2-Hydroxybenzylidene)acetophenone, NSC-37432, NSC170281, STK093271, AKOS000486194, AKOS025309995, FH43279, NSC-170281, NSC-640539, MS-10592, SMR001526790, HY-119931, CS-0078796, CS-0311212, H0234, NS00042209, D90823, AB-016/30005051, SR-01000078236, SR-01000078236-1, trans-3-(O-Hydroxyphenyl)-1-phenyl-2-propen-1-one, (E)-3-(2-hydroxyphenyl)-1-phenyl-prop-2-en-1-one, (2E)-3-(2-Hydroxyphenyl)-1-phenyl-2-propen-1-one #, 6-[(1Z,2Z)-3-Hydroxy-3-phenyl-2-propene-1-ylidene]-2,4-cyclohexadiene-1-one, 211-422-1, 624-468-6
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 37.3
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC(CCC1CCCCC1)C1CCCCC1
Np Classifier Class Chalcones
Deep Smiles O=Ccccccc6))))))/C=C/cccccc6O
Heavy Atom Count 17.0
Classyfire Class Linear 1,3-diarylpropanoids
Scaffold Graph Node Level OC(CCC1CCCCC1)C1CCCCC1
Classyfire Subclass Chalcones and dihydrochalcones
Isotope Atom Count 0.0
Molecular Complexity 277.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id P47199, P11473, Q9UNA4, O75496, P43220, P63092, Q16236, Q77YF9, Q9NUW8, P37840, P06276, n.a., P80457
Iupac Name (E)-3-(2-hydroxyphenyl)-1-phenylprop-2-en-1-one
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Phenylpropanoids and polyketides
Target Id NPT439
Xlogp 3.3
Gsk 4 400 Rule True
Molecular Formula C15H12O2
Scaffold Graph Node Bond Level O=C(C=Cc1ccccc1)c1ccccc1
Prediction Swissadme 0.0
Inchi Key UDOOPSJCRMKSGL-ZHACJKMWSA-N
Silicos It Class Moderately soluble
Fcsp3 0.0
Logs -3.487
Rotatable Bond Count 3.0
Logd 3.188
Synonyms 2-hydroxychalcone
Esol Class Soluble
Functional Groups c/C=C/C(c)=O, cO
Compound Name 2-Hydroxychalcone
Prediction Hob Swissadme 0.0
Exact Mass 224.084
Formal Charge 0.0
Monoisotopic Mass 224.084
Hydrogen Bond Acceptor Count 2.0
Molecular Weight 224.25
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 1.0
Lipinski Rule Of 5 True
Esol -3.9802587411764705
Inchi InChI=1S/C15H12O2/c16-14-9-5-4-8-13(14)10-11-15(17)12-6-2-1-3-7-12/h1-11,16H/b11-10+
Smiles C1=CC=C(C=C1)C(=O)/C=C/C2=CC=CC=C2O
Nring 2.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 1.0
Egan Rule True
Np Classifier Superclass Flavonoids