This website is for informational and educational purposes only. Please do not self-medicate; contact a medical professional for advice before administration. This website is for informational and educational purposes only. Please do not self-medicate; contact a medical professional for advice before administration.

Flavokawain B

PubChem CID: 5356121

Connections displayed (default: 10).
Loading graph...

Compound Synonyms Flavokawain b, 1775-97-9, Flavokavain B, (E)-1-(2-hydroxy-4,6-dimethoxyphenyl)-3-phenylprop-2-en-1-one, 4',6'-Dimethoxy-2'-hydroxychalcone, Flavokavin B, Flavokawin B, 2-Propen-1-one, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-phenyl-, (2E)-, 2'-Hydroxy-4',6'-dimethoxychalcone, CHEBI:65899, R9WC6SM4UQ, PERSICOCHALCONE, UNII-R9WC6SM4UQ, NSC-51351, (E)-2'-Hydroxy-4',6'-dimethoxychalcone, MLS000737282, (2E)-1-(2-hydroxy-4,6-dimethoxyphenyl)-3-phenylprop-2-en-1-one, 76554-24-0, CHALCONE,2-HYDROXY-4,6-DIMETHYL, 2-Propen-1-one, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-phenyl-, (E)-, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-phenyl-2-propen-1-one, (2E)-1-(2-HYDROXY-4,6-DIMETHOXYPHENYL)-3-PHENYL-2-PROPEN-1-ONE, CARDAMONIN-4'-METHYL ETHER, MFCD00075877, Spectrum5_000188, Flavokawain B (Standard), CHALCONE,6-DIMETHYL, BSPBio_001873, SPECTRUM201610, CHEMBL104255, MEGxp0_001270, SCHEMBL1675987, CHEBI:92523, HY-N2132R, QKQLSQLKXBHUSO-CMDGGOBGSA-N, DTXSID601028794, HMS2267O16, HY-N2132, NSC51351, BDBM50491168, CCG-38384, LMPK12120246, s9412, AKOS027383422, FD66669, NCGC00095512-01, NCGC00095512-02, AC-34272, Chalcone, 2'-hydroxy-4',6'-dimethoxy-, SMR000528248, CS-0018683, SR-01000777225, Q5458167, SR-01000777225-3, BRD-K30296925-001-02-1, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-phenylprop-2-en-1-one, 1175-97-9, 2'-Hydroxy-4',6'-dimethoxychalcone, (2E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-phenyl-2-propen-1-one
Topological Polar Surface Area 55.8
Hydrogen Bond Donor Count 1.0
Heavy Atom Count 21.0
Description Found in kava (Piper methysticum), FDA advises against use of kava in food due to potential risk of severe liver damage (2002)
Isotope Atom Count 0.0
Molecular Complexity 360.0
Database Name cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id P47199, Q99714, Q03164, P10636, P51450, Q194T2, P04637, Q13315, P08684, O75164, Q9UIF8, Q96QE3, P11473, P84022, P08659, O94782, P11021, Q9UNQ0, O75496, Q99700, P43220, O42275, P81908, Q9NUW8, O75874, P14916, Q9Y6L6, Q9NPD5, Q03431, P63092, n.a., Q9HBH9
Iupac Name (E)-1-(2-hydroxy-4,6-dimethoxyphenyl)-3-phenylprop-2-en-1-one
Prediction Hob 1.0
Class Linear 1,3-diarylpropanoids
Target Id NPT149, NPT1038, NPT51, NPT539, NPT524, NPT109
Xlogp 3.8
Superclass Phenylpropanoids and polyketides
Subclass Chalcones and dihydrochalcones
Molecular Formula C17H16O4
Prediction Swissadme 0.0
Inchi Key QKQLSQLKXBHUSO-CMDGGOBGSA-N
Fcsp3 0.1176470588235294
Logs -4.992
Rotatable Bond Count 5.0
State Solid
Logd 3.38
Synonyms 2'-Hydroxy-4',6'-dimethoxychalcone, 4',6'-Dimethoxy-2'-hydroxychalcone, CHALCONE,2-HYDROXY-4,6-DIMETHYL, Flavokawain B, Flavokawin B, CHALCONE,2-hydroxy-4,6-dimethyl, Flavokawain b, Flavokawin b, Flavokavin b, Flavokavain b
Substituent Name Chalcone or dihydrochalcone, Cinnamylphenol, 2'-hydroxychalcone, Cinnamic acid or derivatives, Acylphloroglucinol derivative, M-dimethoxybenzene, Dimethoxybenzene, Methoxyphenol, Phloroglucinol derivative, Benzenetriol, Acetophenone, Methoxybenzene, Aryl ketone, Styrene, Phenol ether, Benzoyl, Anisole, Phenol, Alkyl aryl ether, Benzenoid, Monocyclic benzene moiety, Vinylogous acid, Alpha,beta-unsaturated ketone, Enone, Acryloyl-group, Ketone, Ether, Hydrocarbon derivative, Organooxygen compound, Carbonyl group, Aromatic homomonocyclic compound
Compound Name Flavokawain B
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 284.105
Formal Charge 0.0
Monoisotopic Mass 284.105
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 284.31
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 1.0
Molecular Framework Aromatic homomonocyclic compounds
Esol -4.108485342857143
Inchi InChI=1S/C17H16O4/c1-20-13-10-15(19)17(16(11-13)21-2)14(18)9-8-12-6-4-3-5-7-12/h3-11,19H,1-2H3/b9-8+
Smiles COC1=CC(=C(C(=C1)OC)C(=O)/C=C/C2=CC=CC=C2)O
Nring 2.0
Defined Bond Stereocenter Count 1.0
Taxonomy Direct Parent 2'-Hydroxychalcones

  • 1. Outgoing r'ship FOUND_IN to/from Aconitum Variegatum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Artocarpus Altilis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Cephalotaxus Fortunei (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Cheilanthes Fragrans (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Fadogia Agrestis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Helleborus Purpurascens (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 7. Outgoing r'ship FOUND_IN to/from Melia Dubia (Plant) Rel Props:Source_db:npass_chem_all
  • 8. Outgoing r'ship FOUND_IN to/from Ostrya Carpinifolia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 9. Outgoing r'ship FOUND_IN to/from Phonus Arborescens (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 10. Outgoing r'ship FOUND_IN to/from Piper Methysticum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 11. Outgoing r'ship FOUND_IN to/from Pteris Cretica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 12. Outgoing r'ship FOUND_IN to/from Smilax Aspera (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 13. Outgoing r'ship FOUND_IN to/from Stephania Dielsiana (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 14. Outgoing r'ship FOUND_IN to/from Trichosanthes Dioica (Plant) Rel Props:Source_db:npass_chem_all