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[(E)-5-(2,16-dihydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-8,10,12,15,16,17-hexahydro-7H-cyclopenta[a]phenanthren-17-yl)-5-hydroxy-1,1-dimethyl-4-oxo-hex-2-enyl] acetate

PubChem CID: 5353547

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Compound Synonyms NSC106399, CUE, ELATERIN, .alpha., [(E)-5-(2,16-dihydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-8,10,12,15,16,17-hexahydro-7H-cyclopenta[a]phenanthren-17-yl)-5-hydroxy-1,1-dimethyl-4-oxo-hex-2-enyl] acetate, 19-Nor-9.beta.,10.alpha.-lanosta-1,5,23-triene-3,11,22-trione, 2, 16.alpha.,20,25-tetrahydroxy-9-methyl-, 25-acetate, 19-Norlanosta-1,5,23-triene-3,11,22-trione, 25-(acetyloxy)-2,16, 20-trihydroxy-9-methyl-, (9.beta.,10.alpha.,16.alpha.,23E)-, 5-(2,16-Dihydroxy-4,4,9,14-tetramethyl-3,11-dioxoestra-1,5-dien-17-yl)-5-hydroxy-1,1-dimethyl-4-oxo-2-hexenyl acetate
Topological Polar Surface Area 138.0
Hydrogen Bond Donor Count 3.0
Inchi Key NDYMQXYDSVBNLL-OUKQBFOZSA-N
Rotatable Bond Count 6.0
Synonyms &alpha, -elaterin, &alpha, -elaterine, a-Elaterin, Alpha-elaterin, Alpha-elaterine, Cucurbitacin E, Cucurbitacine e, Cucurbitacine-e, CUE, Elaterin, alpha
Heavy Atom Count 40.0
Compound Name [(E)-5-(2,16-dihydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-8,10,12,15,16,17-hexahydro-7H-cyclopenta[a]phenanthren-17-yl)-5-hydroxy-1,1-dimethyl-4-oxo-hex-2-enyl] acetate
Description Cucurbitacin e is a member of the class of compounds known as cucurbitacins. Cucurbitacins are polycyclic compounds containing the tetracyclic cucurbitane nucleus skeleton, 19-(10->9b)-abeo-10alanost-5-ene (also known as 9b-methyl-19-nor lanosta-5-ene), with a variety of oxygenation functionalities at different positions. Cucurbitacin e is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Cucurbitacin e is a bitter tasting compound found in cucumber, muskmelon, and watermelon, which makes cucurbitacin e a potential biomarker for the consumption of these food products.
Exact Mass 556.304
Formal Charge 0.0
Monoisotopic Mass 556.304
Isotope Atom Count 0.0
Molecular Complexity 1270.0
Hydrogen Bond Acceptor Count 8.0
Molecular Weight 556.7
Database Name fooddb_chem_all;pubchem
Covalent Unit Count 1.0
Defined Atom Stereocenter Count 0.0
Iupac Name [(E)-6-(2,16-dihydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-8,10,12,15,16,17-hexahydro-7H-cyclopenta[a]phenanthren-17-yl)-6-hydroxy-2-methyl-5-oxohept-3-en-2-yl] acetate
Total Atom Stereocenter Count 8.0
Total Bond Stereocenter Count 1.0
Inchi InChI=1S/C32H44O8/c1-17(33)40-27(2,3)13-12-23(36)32(9,39)25-21(35)15-29(6)22-11-10-18-19(14-20(34)26(38)28(18,4)5)31(22,8)24(37)16-30(25,29)7/h10,12-14,19,21-22,25,34-35,39H,11,15-16H2,1-9H3/b13-12+
Smiles CC(=O)OC(C)(C)/C=C/C(=O)C(C)(C1C(CC2(C1(CC(=O)C3(C2CC=C4C3C=C(C(=O)C4(C)C)O)C)C)C)O)O
Xlogp 3.2
Defined Bond Stereocenter Count 1.0
Molecular Formula C32H44O8

  • 1. Outgoing r'ship FOUND_IN to/from Citrullus Lanatus (Plant) Rel Props:Source_db:fooddb_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Cucumis Melo (Plant) Rel Props:Source_db:fooddb_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Cucumis Sativus (Plant) Rel Props:Source_db:fooddb_chem_all