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Tonghaosu, (E)-

PubChem CID: 5352496

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Compound Synonyms (E)-Tonghaosu, trans-Enyne-dicycloether, (E)-En-yn-dicycloether, Tonghaosu, (E)-, 50257-98-2, UNII-2G35N7UJFC, 2G35N7UJFC, 1,6-Dioxaspiro(4.4)non-3-ene, 2-(2,4-hexadiyn-1-ylidene)-, (2E)-, (2E)-2-hexa-2,4-diynylidene-1,6-dioxaspiro[4.4]non-3-ene, tonghaosu, En-yn-dicycloether, 1,6-Dioxaspiro[4.4]non-3-ene, 2-(2,4-hexadiynylidene)-, (E)-, 2-(2',4'-hexadiynylidene)-1,6-dioxaspiro(4,4)-non-3-ene, 2-(2',4'-hexadiynylidene)-1,6-dioxaspiro[4,4]-non-3-ene, 1,6-Dioxaspiro[4.4]non-3-ene, 2-(2,4-hexadiyn-1-ylidene)-, (2E)-, trans-En-yn-dicycloether, (Z)-En-yn-dicycloether, 2-(hexa-2,4-diyn-1-ylidene)-1,6-dioxaspiro[4.4]non-3-ene, SCHEMBL3660561, WTRXKCNFPMTAJV-KPKJPENVSA-N, (7E)-4-Deoxy-2,3-dihydromycosinol, FS-10561, EN300-10011193, Q27254693, TRANS-EN-YN-DICYCLOETHER (CONSTITUENT OF CHAMOMILE), (E)-2-(2,4-Hexadiynylidene)-1,6-dioxaspiro[4.4]non-3-ene, (E)-2-(Hexa-2,4-diynylidene)-1,6-dioxaspiro[4.4]non-3-ene, 1,6-Dioxaspiro[4.4]non-3-ene, 2-(2,4-hexadiynylidene)-, (2E)-, trans-2-(Hexa-2,4-diyn-1-ylidene)-1,6-dioxaspiro[4.4]non-3-en, TRANS-EN-YN-DICYCLOETHER (CONSTITUENT OF CHAMOMILE) [DSC], (2E)-2-(2,4-HEXADIYNYLIDENE)-1,6-DIOXASPIRO(4,4)NON-3-ENE
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 18.5
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CCC2(CCCC2)C1
Np Classifier Class Hydrocarbons
Deep Smiles CC#CC#C/C=CC=CCO5)CCCO5
Heavy Atom Count 15.0
Classyfire Class Organooxygen compounds
Description (7e)-4-deoxy-2,3-dihydromycosinol, also known as tonghaosu, is a member of the class of compounds known as ketals. Ketals are acetals derived from ketones by replacement of the oxo group by two hydrocarbyloxy groups R2C(OR)2 ( R not Hydrogen ). This term, once abandoned, has been reinstated as a subclass of acetals (7e)-4-deoxy-2,3-dihydromycosinol is practically insoluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). (7e)-4-deoxy-2,3-dihydromycosinol can be found in german camomile, which makes (7e)-4-deoxy-2,3-dihydromycosinol a potential biomarker for the consumption of this food product.
Scaffold Graph Node Level CC1CCC2(CCCO2)O1
Classyfire Subclass Ethers
Isotope Atom Count 0.0
Molecular Complexity 444.0
Database Name cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name (2E)-2-hexa-2,4-diynylidene-1,6-dioxaspiro[4.4]non-3-ene
Prediction Hob 1.0
Class Organooxygen compounds
Veber Rule True
Classyfire Superclass Organic oxygen compounds
Xlogp 2.5
Superclass Organic oxygen compounds
Subclass Ethers
Gsk 4 400 Rule True
Molecular Formula C13H12O2
Scaffold Graph Node Bond Level C=C1C=CC2(CCCO2)O1
Prediction Swissadme 0.0
Inchi Key WTRXKCNFPMTAJV-KPKJPENVSA-N
Silicos It Class Soluble
Fcsp3 0.3846153846153846
Logs -3.783
Rotatable Bond Count 1.0
State solid
Logd 3.473
Synonyms (7E)-4-Deoxy-2,3-dihydromycosinol, (E)-2-(2,4-Hexadiynylidene)-1,6-dioxaspiro[4.4]non-3-ene, (E)-En-yn-dicycloether, (E)-Tonghaosu, 1,6-Dioxaspiro[4.4]non-3-ene, 2-(2,4-hexadiyn-1-ylidene)-, (2E)-, 1,6-Dioxaspiro[4.4]non-3-ene, 2-(2,4-hexadiynylidene)-, (2E)- (9CI), 1,6-Dioxaspiro[4.4]non-3-ene, 2-(2,4-hexadiynylidene)-, (E)-, trans-2-(Hexa-2,4-diyn-1-ylidene)-1,6-dioxaspiro[4.4]non-3-ene, trans-Enyne-dicycloether, 2-(2',4'-Hexadiynylidene)-1,6-dioxaspiro(4,4)-non-3-ene, Tonghaosu, (e)-en-yn-dicycloether, en-yn-dicycloether, trans-ene-ynedicycloether
Esol Class Soluble
Functional Groups CC#CC#C/C=C1C=CC(C)(OC)O1
Compound Name Tonghaosu, (E)-
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 200.084
Formal Charge 0.0
Monoisotopic Mass 200.084
Hydrogen Bond Acceptor Count 2.0
Molecular Weight 200.23
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 1.0
Molecular Framework Aliphatic heteropolycyclic compounds
Lipinski Rule Of 5 True
Esol -2.6627693999999993
Inchi InChI=1S/C13H12O2/c1-2-3-4-5-7-12-8-10-13(15-12)9-6-11-14-13/h7-8,10H,6,9,11H2,1H3/b12-7+
Smiles CC#CC#C/C=C/1\C=CC2(O1)CCCO2
Nring 4.0
Np Classifier Biosynthetic Pathway Fatty acids
Defined Bond Stereocenter Count 1.0
Egan Rule True
Taxonomy Direct Parent Ketals
Np Classifier Superclass Fatty acyls