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(5R,6S)-5,6-Epoxy-7-megastigmen-9-one

PubChem CID: 5352481

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Compound Synonyms beta-Ionone epoxide, 23267-57-4, 4-(2,2,6-trimethyl-7-oxabicyclo[4.1.0]heptan-1-yl)but-3-en-2-one, (E)-4-(2,2,6-trimethyl-7-oxabicyclo[4.1.0]heptan-1-yl)but-3-en-2-one, .beta.-Ionon-5,6-epoxide, (5R,6S)-5,6-Epoxy-7-megastigmen-9-one, beta-ionone 5,6-epoxide, 4-(2,2,6-Trimethyl-7-oxabicyclo[4.1.0]hept-1-yl)-3-buten-2-one, Epoxy-.beta.-ionone, 5,6-Epoxy-.beta.-ionone, .beta.-Ionone-5,6-epoxide, .beta.-Ionone-5,6-epoxyde, 5,6-.beta.-Ionone epoxide, SCHEMBL1774698, CHEMBL3355912, SCHEMBL17627686, CHEBI:87546, CHEBI:208937, 7-Oxabicyclo[4.1.0]heptane, 3-buten-2-one deriv., (e)-4-(2,2,6-trimethyl-7-oxa-bicyclo[4.1.0]heptan-1-yl)but-3-en-2-one, 4-(1',2'-epoxy-2',6',6'-trimethyl-2'-cyclohex-1'-yl)-3-buten-2-one, (3E)-4-{2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPTAN-1-YL}BUT-3-EN-2-ONE
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 29.6
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2CC2C1
Np Classifier Class Apocarotenoids (β-)
Deep Smiles CC=O)/C=C/COC3C)CCCC7C)C
Heavy Atom Count 15.0
Classyfire Class Oxepanes
Description (5r,6s)-5,6-epoxy-7-megastigmen-9-one, also known as 5,6-epoxy-beta-ionone, is a member of the class of compounds known as oxepanes. Oxepanes are compounds containing an oxepane ring, which is a seven-member saturated aliphatic heterocycle with one oxygen and six carbon atoms (5r,6s)-5,6-epoxy-7-megastigmen-9-one is practically insoluble (in water) and an extremely weak acidic compound (based on its pKa). (5r,6s)-5,6-epoxy-7-megastigmen-9-one can be found in garden tomato and root vegetables, which makes (5r,6s)-5,6-epoxy-7-megastigmen-9-one a potential biomarker for the consumption of these food products.
Scaffold Graph Node Level C1CCC2OC2C1
Isotope Atom Count 0.0
Molecular Complexity 329.0
Database Name cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name (E)-4-(2,2,6-trimethyl-7-oxabicyclo[4.1.0]heptan-1-yl)but-3-en-2-one
Prediction Hob 1.0
Class Oxepanes
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 2.0
Superclass Organoheterocyclic compounds
Gsk 4 400 Rule True
Molecular Formula C13H20O2
Scaffold Graph Node Bond Level C1CCC2OC2C1
Prediction Swissadme 1.0
Inchi Key ZTJZJYUGOJYHCU-RMKNXTFCSA-N
Silicos It Class Soluble
Fcsp3 0.7692307692307693
Rotatable Bond Count 2.0
State Solid
Synonyms 4-(2,2,6-Trimethylbicyclo[4.1.0]hept-1-yl)-3-buten-2-one, 9CI, 5,6-Epoxy-5,6-dihydro-b-ionone, 5,6-Epoxy-beta-ionone, 5,6-epoxy-β-ionone, beta-ionone epoxide, β- ionone epoxide, β-ionone epoxide
Esol Class Soluble
Functional Groups CC(=O)/C=C/C1(C)OC1(C)C
Compound Name (5R,6S)-5,6-Epoxy-7-megastigmen-9-one
Kingdom Organic compounds
Prediction Hob Swissadme 1.0
Exact Mass 208.146
Formal Charge 0.0
Monoisotopic Mass 208.146
Hydrogen Bond Acceptor Count 2.0
Molecular Weight 208.3
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 2.0
Total Bond Stereocenter Count 1.0
Molecular Framework Aliphatic heteropolycyclic compounds
Lipinski Rule Of 5 True
Esol -2.2405661999999995
Inchi InChI=1S/C13H20O2/c1-10(14)6-9-13-11(2,3)7-5-8-12(13,4)15-13/h6,9H,5,7-8H2,1-4H3/b9-6+
Smiles CC(=O)/C=C/C12C(CCCC1(O2)C)(C)C
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 1.0
Egan Rule True
Taxonomy Direct Parent Oxepanes
Np Classifier Superclass Apocarotenoids

  • 1. Outgoing r'ship FOUND_IN to/from Citrullus Lanatus (Plant) Rel Props:Source_db:fooddb_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Codiaeum Variegatum (Plant) Rel Props:Reference:https://doi.org/10.1080/0972060x.2017.1422440
  • 3. Outgoing r'ship FOUND_IN to/from Craibiodendron Yunnanense (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Crocus Sativus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Nelumbo Nucifera (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Origanum Vulgare (Plant) Rel Props:Reference:https://doi.org/10.1080/0972060x.2007.10643545
  • 7. Outgoing r'ship FOUND_IN to/from Pachira Aquatica (Plant) Rel Props:Reference:https://doi.org/10.1080/0972060x.2019.1571950
  • 8. Outgoing r'ship FOUND_IN to/from Taxus Wallichiana (Plant) Rel Props:Reference:https://doi.org/10.1080/0972060x.2012.10644112
  • 9. Outgoing r'ship FOUND_IN to/from Trifolium Repens (Plant) Rel Props:Reference:https://doi.org/10.1080/10412905.2010.9700417