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Pressyn

PubChem CID: 53477739

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Compound Synonyms 8-L-Lysine vasopressin, Pressyn, 3-(Phenylalanine)-8-lysine oxytocin, BDBM627975, CVD-0019448, Q60496436, 6-amino-2-{[(2S)-1-{[(4R,7S,10S,13S,16S,19R)-19-amino-13-benzyl-10-(2-carbamoylethyl)-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)hexanamide
Topological Polar Surface Area 476.0
Hydrogen Bond Donor Count 13.0
Heavy Atom Count 73.0
Description Antidiuretic hormone, also known commonly as vasopressin, is a nine amino acid peptide secreted from the posterior pituitary. Within hypothalamic neurons, the hormone is packaged in secretory vesicles with a carrier protein called neurophysin, and both are released upon hormone secretion. [HMDB]
Isotope Atom Count 0.0
Molecular Complexity 1960.0
Database Name cmaup_ingredients;fooddb_chem_all;pubchem
Defined Atom Stereocenter Count 7.0
Enzyme Uniprot Id P30518, Q93034, Q6W5P4
Iupac Name (2S)-N-[6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
Prediction Hob 0.0
Xlogp -3.9
Molecular Formula C46H65N13O12S2
Prediction Swissadme 0.0
Inchi Key BJFIDCADFRDPIO-ZCCHBGLBSA-N
Fcsp3 0.5
Logs -3.16
Rotatable Bond Count 19.0
State Solid
Logd 0.688
Synonyms 3-(Phenylalanine)-8-lysine oxytocin, 8-L-Lysine vasopressin, ADH, Antidiuretic hormone, Diapid, Pitressin, Pitressin Tannate, Pressyn
Compound Name Pressyn
Prediction Hob Swissadme 0.0
Exact Mass 1055.43
Formal Charge 0.0
Monoisotopic Mass 1055.43
Hydrogen Bond Acceptor Count 16.0
Molecular Weight 1056.2
Covalent Unit Count 1.0
Total Atom Stereocenter Count 8.0
Total Bond Stereocenter Count 0.0
Esol -5.8455256356164345
Inchi InChI=1S/C46H65N13O12S2/c47-17-5-4-9-29(40(65)52-22-38(51)63)54-45(70)35-10-6-18-59(35)46(71)34-24-73-72-23-28(48)39(64)55-31(20-26-11-13-27(60)14-12-26)43(68)56-32(19-25-7-2-1-3-8-25)42(67)53-30(15-16-36(49)61)41(66)57-33(21-37(50)62)44(69)58-34/h1-3,7-8,11-14,28-35,60H,4-6,9-10,15-24,47-48H2,(H2,49,61)(H2,50,62)(H2,51,63)(H,52,65)(H,53,67)(H,54,70)(H,55,64)(H,56,68)(H,57,66)(H,58,69)/t28-,29?,30-,31-,32-,33-,34-,35-/m0/s1
Smiles C1C[C@H](N(C1)C(=O)[C@@H]2CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)N)C(=O)NC(CCCCN)C(=O)NCC(=O)N
Nring 5.0
Defined Bond Stereocenter Count 0.0

  • 1. Outgoing r'ship FOUND_IN to/from Justicia Adhatoda (Plant) Rel Props:Source_db:cmaup_ingredients