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(18S)-12-methoxy-17,17-dimethyl-4,6,10-trioxa-17-azoniahexacyclo[16.3.1.03,7.08,21.011,20.014,19]docosa-1,3(7),8(21),11,13,19-hexaene

PubChem CID: 5321916

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 36.9
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CC2CCC3CCC4C5CCCC5CC5CC(C1)C2C3C54
Np Classifier Class Isoquinoline alkaloids, Aporphine alkaloids
Deep Smiles COcccCC[N+][C@@H]c6c-ccCOc%146)))cOCOc5cc9C%13)))))))))))))C)C
Heavy Atom Count 26.0
Classyfire Class Aporphines
Scaffold Graph Node Level C1CC2CCC3OCC4C5OCOC5CC5CC(N1)C2C3C54
Isotope Atom Count 0.0
Molecular Complexity 582.0
Database Name cmaup_ingredients;imppat_phytochem;pubchem
Defined Atom Stereocenter Count 1.0
Iupac Name (18S)-12-methoxy-17,17-dimethyl-4,6,10-trioxa-17-azoniahexacyclo[16.3.1.03,7.08,21.011,20.014,19]docosa-1,3(7),8(21),11,13,19-hexaene
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 2.8
Gsk 4 400 Rule True
Molecular Formula C21H22NO4+
Scaffold Graph Node Bond Level c1cc2c3c4c1CC[NH2+]C4Cc1cc4c(c(c1-3)CO2)OCO4
Prediction Swissadme 1.0
Inchi Key CIRTUANNSSIDGZ-AWEZNQCLSA-N
Silicos It Class Poorly soluble
Fcsp3 0.4285714285714285
Logs -1.457
Rotatable Bond Count 1.0
Logd 0.61
Synonyms (s)-thalphenine, thalphenine
Esol Class Moderately soluble
Functional Groups C[N+](C)(C)C, c1cOCO1, cOC
Compound Name (18S)-12-methoxy-17,17-dimethyl-4,6,10-trioxa-17-azoniahexacyclo[16.3.1.03,7.08,21.011,20.014,19]docosa-1,3(7),8(21),11,13,19-hexaene
Prediction Hob Swissadme 1.0
Exact Mass 352.155
Formal Charge 1.0
Monoisotopic Mass 352.155
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 352.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -4.083380461538463
Inchi InChI=1S/C21H22NO4/c1-22(2)5-4-11-7-15(23-3)21-19-17-12(6-14(22)18(11)19)8-16-20(26-10-25-16)13(17)9-24-21/h7-8,14H,4-6,9-10H2,1-3H3/q+1/t14-/m0/s1
Smiles C[N+]1(CCC2=CC(=C3C4=C2[C@@H]1CC5=CC6=C(C(=C54)CO3)OCO6)OC)C
Nring 6.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Coleonema Pulchellum (Plant) Rel Props:Source_db:cmaup_ingredients
  • 2. Outgoing r'ship FOUND_IN to/from Corydalis Solida (Plant) Rel Props:Source_db:cmaup_ingredients
  • 3. Outgoing r'ship FOUND_IN to/from Daniellia Oliveri (Plant) Rel Props:Source_db:cmaup_ingredients
  • 4. Outgoing r'ship FOUND_IN to/from Phellodendron Amurense (Plant) Rel Props:Source_db:cmaup_ingredients
  • 5. Outgoing r'ship FOUND_IN to/from Picea Sitchensis (Plant) Rel Props:Source_db:cmaup_ingredients
  • 6. Outgoing r'ship FOUND_IN to/from Tamarix Chinensis (Plant) Rel Props:Source_db:cmaup_ingredients
  • 7. Outgoing r'ship FOUND_IN to/from Thalictrum Minus (Plant) Rel Props:Source_db:cmaup_ingredients
  • 8. Outgoing r'ship FOUND_IN to/from Thalictrum Rugosum (Plant) Rel Props:Source_db:cmaup_ingredients