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4-Coumaric acid methyl ester

PubChem CID: 5319562

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Compound Synonyms Methyl 4-hydroxycinnamate, 19367-38-5, Methyl p-coumarate, methyl 3-(4-hydroxyphenyl)acrylate, 3943-97-3, Methyl p-hydroxycinnamate, 4-Hydroxycinnamic acid methyl ester, (E)-Methyl 3-(4-hydroxyphenyl)acrylate, 4-Coumaric acid methyl ester, p-Hydroxycinnamic acid methyl ester, Methyl 4-coumarate, methyl 3-(4-hydroxyphenyl)prop-2-enoate, Methyl-p-coumarate, (E)-Methyl 4-coumarate, pCAME, methyl (E)-3-(4-hydroxyphenyl)prop-2-enoate, p-Coumaric acid methyl ester, methyl coumarate, Methyl trans-p-Coumarate, Methyl Trans-P-Coumaric Acid, CHEMBL146816, 2-Propenoic acid, 3-(4-hydroxyphenyl)-, methyl ester, (2E)-, Cinnamic acid, p-hydroxy-, methyl ester, P-Hydroxy Cinnamic Acid Methyl Ester, methyl 4-hydroxy cinnamate, Methyl ester of p-Hydroxycinnamic acid, NSC 154578, Methyl (E)-3-(4-hydroxyphenyl)acrylate, 2-Propenoic acid, 3-(4-hydroxyphenyl)-, methyl ester, CHEBI:86904, 3-(4-hydroxy-phenyl)-acrylic acid methyl ester, NSC-154578, MFCD00157167, Cinnamic acid, p-hydroxy-, methyl ester (8CI), methyl (2E)-3-(4-hydroxyphenyl)prop-2-enoate, 2-Propenoic acid, 3-(4-hydroxyphenyl)-, methyl ester (9CI), EINECS 223-531-1, AI3-31901, DTXSID101315877, p-coumaric methyl ester, coumaric acid methyl ester, bmse000605, bmse010222, para-coumaric acid methyl ester, Trans methyl 4-hydroxycinnamate, Methyl trans-4-Hydroxycinnamate, JS-071C, CHEBI:194094, (E)-4-coumaric acid methyl ester, 2-Propenoic acid, 3-(4-hydroxyphenyl)-, methyl ester, (E)-, DTXCID801745760, GLXC-04356, trans-p-Coumaric Acid Methyl Ester, HY-N1434, HY-N2492, BDBM50428389, NSC154578, s3873, AKOS000295941, CCG-266412, CS-W020031, FM25438, AC-10319, AC-34620, trans-4-Hydroxycinnamic Acid Methyl Ester, methyl (2E)-3-(4-hydroxyphenyl)acrylate, CS-0022763, M2259, Methyl 3-(4-hydroxyphenyl)-2-propenoate #, NS00048694, E-3-(4-hydroxyphenyl)acrylic acid methyl ester, EN300-254894, METHYL 3-(4-HYDROXYPHENYL)-2-PROPENOATE, AG-690/03019022, E-3-(4-hydroxy-phenyl)-acrylic acid methyl ester, (E)-3-(4-hydroxy-phenyl)-acrylic acid methylester, (E)-3-(4-hydroxyphenyl)-acrylic acid methyl ester, Q63409893, Z24946550, (2E)-3-(4-Hydroxyphenyl)-2-propenoic acid methyl ester, (E)-4-Hydroxycinnamic acid methyl ester, (E)-p-Hydroxycinnamic acid methyl est er, 802-167-2, HF6
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 46.5
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCCCC1
Np Classifier Class Cinnamic acids and derivatives
Deep Smiles COC=O)/C=C/cccccc6))O
Heavy Atom Count 13.0
Classyfire Class Cinnamic acids and derivatives
Scaffold Graph Node Level C1CCCCC1
Classyfire Subclass Hydroxycinnamic acids and derivatives
Isotope Atom Count 0.0
Molecular Complexity 190.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id P47199, n.a., Q9ULX7, O43570, Q16790, P43166, P00918, P00915, A0A0C7ACN7, P14679
Iupac Name methyl (E)-3-(4-hydroxyphenyl)prop-2-enoate
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Phenylpropanoids and polyketides
Target Id NPT954, NPT949, NPT948, NPT955, NPT233, NPT947, NPT741
Xlogp 2.3
Gsk 4 400 Rule True
Molecular Formula C10H10O3
Scaffold Graph Node Bond Level c1ccccc1
Prediction Swissadme 0.0
Inchi Key NITWSHWHQAQBAW-QPJJXVBHSA-N
Silicos It Class Soluble
Fcsp3 0.1
Logs -1.77
Rotatable Bond Count 3.0
Logd 2.554
Synonyms methyl p-hydroxycinnamate, methyl-p-hydroxycinnamate
Esol Class Soluble
Functional Groups c/C=C/C(=O)OC, cO
Compound Name 4-Coumaric acid methyl ester
Prediction Hob Swissadme 0.0
Exact Mass 178.063
Formal Charge 0.0
Monoisotopic Mass 178.063
Hydrogen Bond Acceptor Count 3.0
Molecular Weight 178.18
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 1.0
Lipinski Rule Of 5 True
Esol -2.5120978615384613
Inchi InChI=1S/C10H10O3/c1-13-10(12)7-4-8-2-5-9(11)6-3-8/h2-7,11H,1H3/b7-4+
Smiles COC(=O)/C=C/C1=CC=C(C=C1)O
Nring 1.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 1.0
Egan Rule True
Np Classifier Superclass Phenylpropanoids (C6-C3)

  • 1. Outgoing r'ship FOUND_IN to/from Aframomum Melegueta (Plant) Rel Props:Source_db:npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Alchornea Cordifolia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Alpinia Blepharocalyx (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Alstonia Angustiloba (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Amomum Daniellii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Anisomeles Indica (Plant) Rel Props:Reference:ISBN:9788172361792
  • 7. Outgoing r'ship FOUND_IN to/from Annona Cherimola (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 8. Outgoing r'ship FOUND_IN to/from Artemisia Pectinata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 9. Outgoing r'ship FOUND_IN to/from Atalantia Wightii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 10. Outgoing r'ship FOUND_IN to/from Baccharis Grandicapitulata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 11. Outgoing r'ship FOUND_IN to/from Balanophora Japonica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
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  • 26. Outgoing r'ship FOUND_IN to/from Dracocephalum Ruyschiana (Plant) Rel Props:Source_db:cmaup_ingredients
  • 27. Outgoing r'ship FOUND_IN to/from Duranta Erecta (Plant) Rel Props:Reference:ISBN:9770972795006; ISBN:9788185042084
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  • 32. Outgoing r'ship FOUND_IN to/from Gutierrezia Dracunculoides (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
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  • 39. Outgoing r'ship FOUND_IN to/from Lasianthaea Podocephala (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 40. Outgoing r'ship FOUND_IN to/from Lathyrus Tingitanus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 41. Outgoing r'ship FOUND_IN to/from Lupinus Cosentinii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 42. Outgoing r'ship FOUND_IN to/from Melampodium Leucanthum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 43. Outgoing r'ship FOUND_IN to/from Microtropis Fokienensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 44. Outgoing r'ship FOUND_IN to/from Morella Pensylvanica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 45. Outgoing r'ship FOUND_IN to/from Papaver Pseudocanescens (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 46. Outgoing r'ship FOUND_IN to/from Pellacalyx Axillaris (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 47. Outgoing r'ship FOUND_IN to/from Peucedanum Oroselinum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 48. Outgoing r'ship FOUND_IN to/from Phlomis Crinita (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 49. Outgoing r'ship FOUND_IN to/from Piper Brachystachyum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 50. Outgoing r'ship FOUND_IN to/from Plectranthus Caninus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 51. Outgoing r'ship FOUND_IN to/from Polygonum Lapathifolium (Plant) Rel Props:Source_db:npass_chem_all
  • 52. Outgoing r'ship FOUND_IN to/from Psidium Acutangulum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 53. Outgoing r'ship FOUND_IN to/from Pueraria Montana (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 54. Outgoing r'ship FOUND_IN to/from Rauvolfia Salicifolia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 55. Outgoing r'ship FOUND_IN to/from Renealmia Alpinia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 56. Outgoing r'ship FOUND_IN to/from Rhododendron Mucronulatum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 57. Outgoing r'ship FOUND_IN to/from Rubus Niveus (Plant) Rel Props:Source_db:npass_chem_all
  • 58. Outgoing r'ship FOUND_IN to/from Schisandra Sphenanthera (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 59. Outgoing r'ship FOUND_IN to/from Securinega Suffruticosa (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 60. Outgoing r'ship FOUND_IN to/from Selinum Libanotis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 61. Outgoing r'ship FOUND_IN to/from Senecio Congestus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 62. Outgoing r'ship FOUND_IN to/from Sideritis Dasygnaphala (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 63. Outgoing r'ship FOUND_IN to/from Sorghum Bicolor (Plant) Rel Props:Reference:https://www.ncbi.nlm.nih.gov/pubmed/12934645
  • 64. Outgoing r'ship FOUND_IN to/from Stellaria Media (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 65. Outgoing r'ship FOUND_IN to/from Strychnos Spinosa (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 66. Outgoing r'ship FOUND_IN to/from Tephroseris Kirilowii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 67. Outgoing r'ship FOUND_IN to/from Tephrosia Purpurea (Plant) Rel Props:Source_db:npass_chem_all
  • 68. Outgoing r'ship FOUND_IN to/from Tetradium Glabrifolium (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 69. Outgoing r'ship FOUND_IN to/from Vitex Rotundifolia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 70. Outgoing r'ship FOUND_IN to/from Zephyranthes Flava (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all