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5-Hydroxy-8-[(2-hydroxy-4-methoxyphenyl)methyl]-6,7-dimethoxy-2-phenyl-2,3-dihydrochromen-4-one

PubChem CID: 5319166

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 94.5
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CC(C2CCCCC2)CC2C(CC3CCCCC3)CCCC12
Np Classifier Class Flavanones
Deep Smiles COcccccc6)O))CccOC))cOC))ccc6OCCC6=O)))cccccc6))))))))))O
Heavy Atom Count 32.0
Classyfire Class Diarylheptanoids
Scaffold Graph Node Level OC1CC(C2CCCCC2)OC2C(CC3CCCCC3)CCCC12
Classyfire Subclass Linear diarylheptanoids
Isotope Atom Count 0.0
Molecular Complexity 621.0
Database Name cmaup_ingredients;imppat_phytochem;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name 5-hydroxy-8-[(2-hydroxy-4-methoxyphenyl)methyl]-6,7-dimethoxy-2-phenyl-2,3-dihydrochromen-4-one
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Phenylpropanoids and polyketides
Xlogp 4.6
Gsk 4 400 Rule False
Molecular Formula C25H24O7
Scaffold Graph Node Bond Level O=C1CC(c2ccccc2)Oc2c(Cc3ccccc3)cccc21
Prediction Swissadme 0.0
Inchi Key NXQXXNMFWZSKBH-UHFFFAOYSA-N
Silicos It Class Poorly soluble
Fcsp3 0.24
Logs -4.293
Rotatable Bond Count 6.0
Logd 3.393
Synonyms macrophyllin
Esol Class Moderately soluble
Functional Groups cC(C)=O, cO, cOC
Compound Name 5-Hydroxy-8-[(2-hydroxy-4-methoxyphenyl)methyl]-6,7-dimethoxy-2-phenyl-2,3-dihydrochromen-4-one
Prediction Hob Swissadme 0.0
Exact Mass 436.152
Formal Charge 0.0
Monoisotopic Mass 436.152
Hydrogen Bond Acceptor Count 7.0
Molecular Weight 436.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -5.451702000000001
Inchi InChI=1S/C25H24O7/c1-29-16-10-9-15(18(26)12-16)11-17-23-21(22(28)25(31-3)24(17)30-2)19(27)13-20(32-23)14-7-5-4-6-8-14/h4-10,12,20,26,28H,11,13H2,1-3H3
Smiles COC1=CC(=C(C=C1)CC2=C3C(=C(C(=C2OC)OC)O)C(=O)CC(O3)C4=CC=CC=C4)O
Nring 4.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Flavonoids

  • 1. Outgoing r'ship FOUND_IN to/from Maesa Macrophylla (Plant) Rel Props:Reference:ISBN:9770972795006
  • 2. Outgoing r'ship FOUND_IN to/from Uvaria Macrophylla (Plant) Rel Props:Source_db:cmaup_ingredients