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11-Hydroxyrankinidine

PubChem CID: 5318332

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Compound Synonyms 11-Hydroxyrankinidine, 122590-03-8, (7Z)-7-ethylidene-6'-hydroxy-1'-methoxyspiro[11-oxa-5-azatricyclo[6.3.1.04,9]dodecane-2,3'-indole]-2'-one, Nb-Demethyl-11-hydroxyhumantenine, Humantenine, 4-demethyl-11-hydroxy-, Spiro(3H-indole-3,8'(7'H)-(4,7)methanooxepino(4,3-b)pyridin)-2(1H)-one, 3'-ethylidene-1',2',3',4',4'a,5',9',9'a-octahydro-6-hydroxy-1-methoxy-, (3S,3'Z,4'R,4'aS,7'R,9'aS)-, DA-49071
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 71.0
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CCC2CC3(C(C)CC4CCCCC43)C3CCC2C1C3
Np Classifier Class Corynanthe type
Deep Smiles CONcccO)ccc6CC9=O))CCNC/C=CC))/CCC9OCC%106
Heavy Atom Count 26.0
Classyfire Class Gelsemium alkaloids
Scaffold Graph Node Level CC1CNC2CC3(C(O)NC4CCCCC43)C3CC1C2CO3
Isotope Atom Count 0.0
Molecular Complexity 637.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name (7Z)-7-ethylidene-6'-hydroxy-1'-methoxyspiro[11-oxa-5-azatricyclo[6.3.1.04,9]dodecane-2,3'-indole]-2'-one
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 0.9
Gsk 4 400 Rule True
Molecular Formula C20H24N2O4
Scaffold Graph Node Bond Level C=C1CNC2CC3(C(=O)Nc4ccccc43)C3CC1C2CO3
Prediction Swissadme 1.0
Inchi Key FALAMCOLIJTCTR-QDEBKDIKSA-N
Silicos It Class Soluble
Fcsp3 0.55
Logs -3.792
Rotatable Bond Count 1.0
Logd 2.987
Synonyms 11-hydroxyrankinidine
Esol Class Soluble
Functional Groups C/C=C(/C)C, CNC, COC, cN(OC)C(C)=O, cO
Compound Name 11-Hydroxyrankinidine
Prediction Hob Swissadme 1.0
Exact Mass 356.174
Formal Charge 0.0
Monoisotopic Mass 356.174
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 356.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 5.0
Total Bond Stereocenter Count 1.0
Lipinski Rule Of 5 True
Esol -2.721585630769231
Inchi InChI=1S/C20H24N2O4/c1-3-11-9-21-16-8-20(18-7-13(11)14(16)10-26-18)15-5-4-12(23)6-17(15)22(25-2)19(20)24/h3-6,13-14,16,18,21,23H,7-10H2,1-2H3/b11-3+
Smiles C/C=C/1\CNC2CC3(C4CC1C2CO4)C5=C(C=C(C=C5)O)N(C3=O)OC
Nring 2.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 1.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Codonopsis Pilosula (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Gelsemium Elegans (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all