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Gravacridonediol

PubChem CID: 5317836

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Compound Synonyms Gravacridonediol, 37551-75-0, 2-(1,2-Dihydroxy-1-methylethyl)-1,11-dihydro-5-hydroxy-11-methylfuro[2,3-c]acridin-6(2H)-one, Gravacridondiol, CHEMBL562500, CHEBI:195185, DTXSID301120214, DB-259875, 2-(1,2-dihydroxypropan-2-yl)-5-hydroxy-11-methyl-1,2-dihydrouro[2,3-c]acridin-6-one, 2-(1,2-dihydroxypropan-2-yl)-5-hydroxy-11-methyl-1H,2H,6H,11H-furo[2,3-c]acridin-6-one
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 90.2
Hydrogen Bond Donor Count 3.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1C2CCCCC2CC2C3CCCC3CCC12
Np Classifier Class Acridone alkaloids
Deep Smiles OCCCOccC5)cccc6)O))c=O)ccn6C))cccc6)))))))))))))O)C
Heavy Atom Count 25.0
Classyfire Class Quinolines and derivatives
Scaffold Graph Node Level OC1C2CCCCC2NC2C3CCOC3CCC12
Classyfire Subclass Benzoquinolines
Isotope Atom Count 0.0
Molecular Complexity 542.0
Database Name cmaup_ingredients;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id P08183
Iupac Name 2-(1,2-dihydroxypropan-2-yl)-5-hydroxy-11-methyl-1,2-dihydrofuro[2,3-c]acridin-6-one
Prediction Hob 1.0
Class Quinolines and derivatives
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 2.3
Superclass Organoheterocyclic compounds
Subclass Benzoquinolines
Gsk 4 400 Rule True
Molecular Formula C19H19NO5
Scaffold Graph Node Bond Level O=c1c2ccccc2[nH]c2c3c(ccc12)OCC3
Prediction Swissadme 1.0
Inchi Key RQAGSTDFTGSIGB-UHFFFAOYSA-N
Silicos It Class Soluble
Fcsp3 0.3157894736842105
Logs -4.027
Rotatable Bond Count 2.0
State Solid
Logd 1.687
Synonyms 2-(1,2-Dihydroxy-1-methylethyl)-1,11-dihydro-5-hydroxy-11-methylfuro[2,3-c]acridin-6(2H)-one, gravacridondiol, gravacridonediol
Esol Class Soluble
Functional Groups CO, c=O, cO, cOC, cn(c)C
Compound Name Gravacridonediol
Kingdom Organic compounds
Prediction Hob Swissadme 1.0
Exact Mass 341.126
Formal Charge 0.0
Monoisotopic Mass 341.126
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 341.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 2.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aromatic heteropolycyclic compounds
Lipinski Rule Of 5 True
Esol -4.3178506
Inchi InChI=1S/C19H19NO5/c1-19(24,9-21)15-7-11-14(25-15)8-13(22)16-17(11)20(2)12-6-4-3-5-10(12)18(16)23/h3-6,8,15,21-22,24H,7,9H2,1-2H3
Smiles CC(CO)(C1CC2=C(O1)C=C(C3=C2N(C4=CC=CC=C4C3=O)C)O)O
Nring 4.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Taxonomy Direct Parent Acridones
Np Classifier Superclass Anthranilic acid alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Ruta Graveolens (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Thamnosma Rhodesica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all