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2-[[(2R,13bS)-11-hydroxy-2-methoxy-2,6,8,9-tetrahydro-1H-indolo[7a,1-a]isoquinolin-12-yl]oxysulfonyl]acetic acid

PubChem CID: 5317202

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 122.0
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule True
Scaffold Graph Level C1CCC2C(C1)CCC1CCC3CCCCC312
Np Classifier Class Indolizidine alkaloids
Deep Smiles CO[C@H]C=CC=CCN[C@]5C9)cccOS=O)=O)CC=O)O)))))ccc6CC%10))))O
Heavy Atom Count 28.0
Classyfire Class Erythrina alkaloids
Scaffold Graph Node Level C1CCC2C(C1)CCN1CCC3CCCCC321
Classyfire Subclass Erythrinanes
Isotope Atom Count 0.0
Molecular Complexity 802.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 2.0
Iupac Name 2-[[(2R,13bS)-11-hydroxy-2-methoxy-2,6,8,9-tetrahydro-1H-indolo[7a,1-a]isoquinolin-12-yl]oxysulfonyl]acetic acid
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp -1.3
Gsk 4 400 Rule False
Molecular Formula C19H21NO7S
Scaffold Graph Node Bond Level C1=CC2=CCN3CCc4ccccc4C23CC1
Prediction Swissadme 0.0
Inchi Key FESQVDOEHMLQJE-LIRRHRJNSA-N
Silicos It Class Soluble
Fcsp3 0.4210526315789473
Logs -4.343
Rotatable Bond Count 5.0
Logd 3.144
Synonyms erysothiopine
Esol Class Very soluble
Functional Groups CC(=O)O, CC=C(C)C=CC, CN(C)C, COC, cO, cOS(C)(=O)=O
Compound Name 2-[[(2R,13bS)-11-hydroxy-2-methoxy-2,6,8,9-tetrahydro-1H-indolo[7a,1-a]isoquinolin-12-yl]oxysulfonyl]acetic acid
Prediction Hob Swissadme 0.0
Exact Mass 407.104
Formal Charge 0.0
Monoisotopic Mass 407.104
Hydrogen Bond Acceptor Count 8.0
Molecular Weight 407.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 2.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -1.3694746285714292
Inchi InChI=1S/C19H21NO7S/c1-26-14-3-2-13-5-7-20-6-4-12-8-16(21)17(9-15(12)19(13,20)10-14)27-28(24,25)11-18(22)23/h2-3,5,8-9,14,21H,4,6-7,10-11H2,1H3,(H,22,23)/t14-,19-/m0/s1
Smiles CO[C@@H]1C[C@@]23C(=CCN2CCC4=CC(=C(C=C34)OS(=O)(=O)CC(=O)O)O)C=C1
Nring 4.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Lysine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Erythrina Abyssinica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Erythrina Arborescens (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Erythrina Folkersii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Erythrina Fusca (Plant) Rel Props:Reference:https://doi.org/10.15482/usda.adc/1239279
  • 5. Outgoing r'ship FOUND_IN to/from Erythrina Glauca (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Erythrina Lithosperma (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 7. Outgoing r'ship FOUND_IN to/from Erythrina Salviiflora (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 8. Outgoing r'ship FOUND_IN to/from Erythrina Variegata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all