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Vertine

PubChem CID: 5315204

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Compound Synonyms Vertine, Cryogenine, 10308-13-1, Vertinealkaloid, Cryogenine (alkaloid), OR77C8W8TA, NSC 272693, UNII-OR77C8W8TA, (+)-VERTINE, VERTINE, (+)-, CHEBI:3929, (10-alpha)-4'',5''-Dimethoxy-2'-hydroxylythran-12-one, (1S,13Z,17S,19R)-9-hydroxy-4,5-dimethoxy-16-oxa-24-azapentacyclo[15.7.1.18,12.02,7.019,24]hexacosa-2,4,6,8,10,12(26),13-heptaen-15-one, (13Z)-9-Hydroxy-4,5-dimethoxy-16-oxa-24-azapentacyclo[15.7.1.18,12.02,7.019,24]hexacosa-2,4,6,8,10,12(26),13-heptaen-15-one, 2'-hydroxy-4'',5''-dimethoxy-10alpha-lythran-12-one, (10.ALPHA.)-4,5-DIMETHOXY-2-HYDROXYLYTHRAN-12-ONE, NSC-272693, (4AR,6S,9Z,20S)-2,3,4,4A,5,6-HEXAHYDRO-14-HYDROXY-17,18-DIMETHOXY-20H-6,20-METHANO-11,15-METHENO-1H,8H-BENZO(G)PYRIDO(2,1-D)(1,5)OXAAZACYCLOHEXADECIN-8-ONE, (4aR,6S,9Z,20S)-2,3,4,4a,5,6-Hexahydro-14-hydroxy-17,18-dimethoxy-20H-6,20-methano-11,15-metheno-1H,8H-benzo[g]pyrido[2,1-d][1,5]oxaazacyclohexadecin-8-one, 20H-6,20-METHANO-11,15-METHENO-1H,8H-BENZO(G)PYRIDO(2,1-D)(1,5)OXAAZACYCLOHEXADECIN-8-ONE, 2,3,4,4A,5,6-HEXAHYDRO-14-HYDROXY-17,18-DIMETHOXY-, (4AR,6S,9Z,20S)-, UNII-S16X2W9YAB, Vertine (7CI,8CI), (1S,13Z,17S,19R)-9-hydroxy-4,5-dimethoxy-16-oxa-24-azapentacyclo(15.7.1.18,12.02,7.019,24)hexacosa-2,4,6,8,10,12(26),13-heptaen-15-one, Lythran-12-one, 2'-hydroxy-4'',5''-dimethoxy-, (10alpha)-, SCHEMBL1119034, CHEMBL1173218, DTXSID201099973, HY-N8458, Lythran-12-one, 2'-hydroxy-4'',5''-dimethoxy-, (10.alpha.)-, AKOS040756358, CS-0144493, Q5190532, (10ALPHA)-4,5-DIMETHOXY-2-HYDROXYLYTHRAN-12-ONE
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 68.2
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CCC2CCCC(C2)C2CCCCC2C2CC(C1)CC1CCCCC12
Np Classifier Class Quinolizidine alkaloids
Deep Smiles COccc-ccc/C=CC=O)O[C@@H]C[C@@H]c%12cc%16OC)))))NCCCC[C@@H]6C%10))))))))))))))ccc6O
Heavy Atom Count 32.0
Classyfire Class Quinolizidines
Scaffold Graph Node Level OC1CCC2CCCC(C2)C2CCCCC2C2CC(CC3CCCCN32)O1
Isotope Atom Count 0.0
Molecular Complexity 698.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 3.0
Iupac Name (1S,13Z,17S,19R)-9-hydroxy-4,5-dimethoxy-16-oxa-24-azapentacyclo[15.7.1.18,12.02,7.019,24]hexacosa-2,4,6,8,10,12(26),13-heptaen-15-one
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 4.6
Gsk 4 400 Rule False
Molecular Formula C26H29NO5
Scaffold Graph Node Bond Level O=C1C=Cc2cccc(c2)-c2ccccc2C2CC(CC3CCCCN32)O1
Prediction Swissadme 1.0
Inchi Key WCZWUYYJZVBKDZ-VMSBZHFZSA-N
Silicos It Class Moderately soluble
Fcsp3 0.4230769230769231
Logs -4.914
Rotatable Bond Count 2.0
Logd 3.819
Synonyms vertine
Esol Class Moderately soluble
Functional Groups CN(C)C, c/C=CC(=O)OC, cO, cOC
Compound Name Vertine
Prediction Hob Swissadme 1.0
Exact Mass 435.205
Formal Charge 0.0
Monoisotopic Mass 435.205
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 435.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 3.0
Total Bond Stereocenter Count 1.0
Lipinski Rule Of 5 True
Esol -5.589973600000001
Inchi InChI=1S/C26H29NO5/c1-30-24-14-19-20(15-25(24)31-2)22-13-18(12-17-5-3-4-10-27(17)22)32-26(29)9-7-16-6-8-23(28)21(19)11-16/h6-9,11,14-15,17-18,22,28H,3-5,10,12-13H2,1-2H3/b9-7-/t17-,18+,22+/m1/s1
Smiles COC1=C(C=C2C(=C1)[C@@H]3C[C@H](C[C@@H]4N3CCCC4)OC(=O)/C=C\C5=CC2=C(C=C5)O)OC
Nring 5.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 1.0
Egan Rule True
Np Classifier Superclass Lysine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Artabotrys Venustus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Eclipta Prostrata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Galium Glaucum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Heimia Salicifolia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Lindsaea Ensifolia (Plant) Rel Props:Source_db:npass_chem_all