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5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-12,12-dimethyl-8a,9,10,11,12a,13-hexahydro-8H-chromeno[7,8-c][2]benzoxepin-4-one

PubChem CID: 5315114

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Compound Synonyms SCHEMBL19665246
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 85.2
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CC(C2CCCCC2)CC2C1CCC1CCC3CCCCC3CC12
Np Classifier Class Isoflavones
Deep Smiles COcccccc6O))))ccc=O)cco6)cCCCCOc7cc%11O))))))CCCC6C)C
Heavy Atom Count 32.0
Classyfire Class Flavonoids
Scaffold Graph Node Level OC1CC(C2CCCCC2)OC2C1CCC1OCC3CCCCC3CC12
Classyfire Subclass Flavones
Isotope Atom Count 0.0
Molecular Complexity 747.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name 5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-12,12-dimethyl-8a,9,10,11,12a,13-hexahydro-8H-chromeno[7,8-c][2]benzoxepin-4-one
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Phenylpropanoids and polyketides
Xlogp 5.9
Gsk 4 400 Rule False
Molecular Formula C26H28O6
Scaffold Graph Node Bond Level O=c1cc(-c2ccccc2)oc2c3c(ccc12)OCC1CCCCC1C3
Prediction Swissadme 0.0
Inchi Key BEKKBGJECYLADF-UHFFFAOYSA-N
Silicos It Class Poorly soluble
Fcsp3 0.4230769230769231
Logs -3.744
Rotatable Bond Count 2.0
Logd 4.174
Synonyms ugonin b
Esol Class Poorly soluble
Functional Groups c=O, cO, cOC, coc
Compound Name 5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-12,12-dimethyl-8a,9,10,11,12a,13-hexahydro-8H-chromeno[7,8-c][2]benzoxepin-4-one
Prediction Hob Swissadme 0.0
Exact Mass 436.189
Formal Charge 0.0
Monoisotopic Mass 436.189
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 436.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 2.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -6.016224800000001
Inchi InChI=1S/C26H28O6/c1-26(2)8-4-5-15-13-31-22-12-20(29)24-19(28)11-21(32-25(24)16(22)10-17(15)26)14-6-7-18(27)23(9-14)30-3/h6-7,9,11-12,15,17,27,29H,4-5,8,10,13H2,1-3H3
Smiles CC1(CCCC2C1CC3=C(C=C(C4=C3OC(=CC4=O)C5=CC(=C(C=C5)O)OC)O)OC2)C
Nring 5.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Isoflavonoids