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Fenretinide

PubChem CID: 5288209

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Compound Synonyms FENRETINIDE, 65646-68-6, N-(4-Hydroxyphenyl)retinamide, 4-HPR, 4-hydroxyphenylretinamide, 4-Hydroxyphenyl retinamide, Retinoic acid p-hydroxyanilide, all-trans-4'-Hydroxyretinanilide, McN-R-1967, Fenretinida, Retinamide, N-(4-hydroxyphenyl)-, Fenretinidum, Fenretinidum [Latin], Rii retinamide, N-(4-Hydroxyphenyl)all-Trans Retinamide, Fenretinide [USAN:INN], Retinoic acid p-hydroxyphenylamide, 4-hydroxy(phenyl)retinamide, 15-[(4-hydroxyphenyl)amino]retinal, CCRIS 3260, 4-(hydroxyphenyl)retinamide, 187EJ7QEXL, MFCD00792674, NSC-760419, BRN 5769490, DTXSID2032005, FENRETINIDE [MI], FENRETINIDE [INN], (2E,4E,6E,8E)-N-(4-hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenamide, FENRETINIDE [USAN], FENRETINIDE [VANDF], FENRETINIDE [MART.], CHEMBL7301, FENRETINIDE [WHO-DD], MLS002701698, DTXCID0012005, CHEBI:42588, NSC374551, Fenretinidum (Latin), NSC 760419, NSC-374551, (2E,4E,6E,8E)-N-(4-hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenamide, all-trans-n-(4-hydroxyphenyl)retinamide, NCGC00090752-03, Fenretinimide, FENRETINIDE (MART.), N-(4-HYDROXYPHENYL)-ALL-TRANS-VITAMIN A AMIDE, Fenretinida [Spanish], 4HPR, 15-((4-hydroxyphenyl)amino)retinal, SMR001456303, CAS-65646-68-6, SR-01000075917, 4 Hydroxyphenylretinamide, N-(4-Hydroxyphenyl)-trans-Retinamide, UNII-187EJ7QEXL, SYT-101, ST-602, Fenretinide, 4-HPR, p-Hydroxyphenylretinamide, Fenretinide (4-HPR)?, Spectrum5_001939, Fenretinide (USAN/INN), HPR-4, Lopac0_000625, SCHEMBL11703, SCHEMBL11704, BSPBio_001419, MLS001055399, MLS006010811, BML2-E08, N-(4-hydroxyphenyl)-retinamide, SCHEMBL15703189, CHEBI:92493, 15-(4-Hydroxyanilino)retinal #, HMS1361G21, HMS1791G21, HMS1989G21, HMS2089B17, HMS3261N12, HMS3402G21, HMS3412M06, HMS3676M06, Pharmakon1600-01505602, all-trans-N-4'-hydroxyretinanilide, 4-(all-trans-retino-yl)aminophenol, BCP06908, EX-A4102, N-(4-hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraenamide, Tox21_111007, Tox21_200989, Tox21_500625, 1-enyl)nona-2,4,6,8-tetraenamide, BDBM50092055, HSCI1_000112, NSC760419, s5233, AKOS024456572, N-(4-Hydroxyphenyl)retinamide, 4-HPR, Tox21_111007_1, CCG-204713, CS-0789, DB05076, FF23268, LP00625, N-(4-hydroxyphenyl)retinamide, 4-HPR, SDCCGSBI-0050606.P002, dimethyl-9-(2,6,6-trimethylcyclohex-, IDI1_033889, Retinoic acid p-hydroxyanilide, >=95%, NCGC00090752-01, NCGC00090752-02, NCGC00090752-04, NCGC00090752-05, NCGC00090752-06, NCGC00090752-07, NCGC00090752-09, NCGC00090752-10, NCGC00090752-11, NCGC00090752-12, NCGC00090752-20, NCGC00258542-01, NCGC00261310-01, (2E,4E,6E,8E)-N-(4-hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraenamide, AS-59667, BP-13369, HY-15373, SMR000677938, EU-0100625, H1464, NS00069470, D04162, H 7779, (2E,4E,6E,8E)-N-(4-hydroxyphenyl)-3,7-, AB00172992-07, Q5443576, SR-01000075917-1, SR-01000075917-4, BRD-K89085489-001-19-0, BRD-K89085489-001-22-4, BRD-K89085489-001-23-2, (2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid (4-hydroxy-phenyl)-amide, (2E,4E,6E,8E)-N-(4-Hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraenamide, 2,6,8-Nonatetraenamide, N-(4-hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl-, (all-E)-, 3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid (4-hydroxy-phenyl)-amide
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 49.3
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC(CCCCCCCCC1CCCCC1)CC1CCCCC1
Np Classifier Class Cyclophytane diterpenoids
Deep Smiles O=CNcccccc6))O))))))/C=C/C=C/C=C/C=C/C=CC)CCCC6C)C)))))))))C)))))C
Heavy Atom Count 29.0
Classyfire Class Prenol lipids
Scaffold Graph Node Level OC(CCCCCCCCC1CCCCC1)NC1CCCCC1
Classyfire Subclass Retinoids
Isotope Atom Count 0.0
Molecular Complexity 726.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name (2E,4E,6E,8E)-N-(4-hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenamide
Veber Rule True
Classyfire Superclass Lipids and lipid-like molecules
Xlogp 7.3
Gsk 4 400 Rule False
Molecular Formula C26H33NO2
Scaffold Graph Node Bond Level O=C(C=CC=CC=CC=CC1=CCCCC1)Nc1ccccc1
Inchi Key AKJHMTWEGVYYSE-FXILSDISSA-N
Silicos It Class Poorly soluble
Rotatable Bond Count 6.0
Synonyms fenretinide
Esol Class Moderately soluble
Functional Groups cNC(=O)/C=C(C)/C=C/C=C(C)/C=C/C(C)=C(C)C, cO
Compound Name Fenretinide
Exact Mass 391.251
Formal Charge 0.0
Monoisotopic Mass 391.251
Hydrogen Bond Acceptor Count 2.0
Molecular Weight 391.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 4.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C26H33NO2/c1-19(11-16-24-21(3)10-7-17-26(24,4)5)8-6-9-20(2)18-25(29)27-22-12-14-23(28)15-13-22/h6,8-9,11-16,18,28H,7,10,17H2,1-5H3,(H,27,29)/b9-6+,16-11+,19-8+,20-18+
Smiles CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/C(=O)NC2=CC=C(C=C2)O)/C)/C
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 4.0
Egan Rule False
Np Classifier Superclass Diterpenoids

  • 1. Outgoing r'ship FOUND_IN to/from Aegle Marmelos (Plant) Rel Props:Reference:https://doi.org/10.1080/0972060x.2019.1653796
  • 2. Outgoing r'ship FOUND_IN to/from Justicia Adhatoda (Plant) Rel Props:Reference:https://doi.org/10.1080/0972060x.2016.1260061