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2-Dodecenoic acid

PubChem CID: 5282729

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Compound Synonyms Dodec-2-enoic acid, (E)-dodec-2-enoic acid, trans-2-Dodecenoic acid, 32466-54-9, 2-Dodecenoic acid, 4412-16-2, (2E)-dodec-2-enoic acid, (2E)-2-Dodecenoic acid, Dodecenoic acid, 2-Dodecensaeure, trans-dodec-2-enoic acid, Dodec-2-ensaeure, 2E-Lauroleic acid, 2E-Dodecenoic acid, EINECS 224-569-1, 1289-45-8, CHEBI:38371, NSC 59856, C12:1n-10, (2Z)-2-Dodecenoic acid, (E)-2-dodecenoic acid, DTXSID80871073, 2t-Dodecensaeure, Dodec-2-enoicacid, MFCD00045906, Dodecen-(2t)-saeure, trans-2-lauroleic acid, 12:1, n-10 trans, C12:1, n-10 trans, CHEMBL4281333, CHEBI:37162, DTXCID80818746, DTXSID401343611, LMFA01030788, AKOS008105134, AS-57983, WS-00320, AI3-11152, C12:1, CS-0152270, D5660, EN300-65552, EN300-365600, G77635, W16764, Q27117056, Q27117632, Z336127680, 224-569-1, 3X1, 836-106-6
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 37.3
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Np Classifier Class Unsaturated fatty acids
Deep Smiles CCCCCCCCC/C=C/C=O)O
Heavy Atom Count 14.0
Classyfire Class Fatty acyls
Description In humans fatty acids are predominantly formed in the liver and adipose tissue, and mammary glands during lactation. trans-Dodec-2-enoic acid is an intermediate in fatty acid biosynthesis. Specifically, trans-Dodec-2-enoic acid is converted from (R)-3-Hydroxydodecanoic acid via two enzymes, fatty-acid Synthase and 3-Hydroxypalmitoyl- [acyl-carrier-protein] dehydratase (EC: 2.3.1.85 and EC: 4.2.1.61) [HMDB]
Classyfire Subclass Fatty acids and conjugates
Isotope Atom Count 0.0
Molecular Complexity 162.0
Database Name cmaup_ingredients;fooddb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Enzyme Uniprot Id P49327
Uniprot Id O42275, P81908, Q99436
Iupac Name (E)-dodec-2-enoic acid
Prediction Hob 1.0
Class Fatty Acyls
Veber Rule True
Classyfire Superclass Lipids and lipid-like molecules
Xlogp 4.8
Superclass Lipids and lipid-like molecules
Subclass Fatty acids and conjugates
Gsk 4 400 Rule True
Molecular Formula C12H22O2
Prediction Swissadme 0.0
Inchi Key PAWGRNGPMLVJQH-ZHACJKMWSA-N
Silicos It Class Soluble
Fcsp3 0.75
Logs -3.378
Rotatable Bond Count 9.0
State Solid
Logd 2.474
Synonyms (e)-2-Dodecenoate, (e)-2-Dodecenoic acid, 12:1, N-10 trans, 2-Lauroleate, 2-Lauroleic acid, 2t-Dodecensaeure, C12:1, N-10 trans, Dodecen-(2t)-saeure, trans-2-Lauroleate, trans-2-Lauroleic acid, trans-Dodec-2-enoate, (e)-2-dodecenoic acid, 2-dodecenoic acid, 2-dodecenoic-acid, dodec-2-enoic acid, dodecenoic acid, trans-2-dodecenoic acid
Substituent Name Medium-chain fatty acid, Unsaturated fatty acid, Straight chain fatty acid, Monocarboxylic acid or derivatives, Carboxylic acid, Carboxylic acid derivative, Hydrocarbon derivative, Organooxygen compound, Carbonyl group, Aliphatic acyclic compound
Esol Class Soluble
Functional Groups C/C=C/C(=O)O
Compound Name 2-Dodecenoic acid
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 198.162
Formal Charge 0.0
Monoisotopic Mass 198.162
Hydrogen Bond Acceptor Count 2.0
Molecular Weight 198.3
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 1.0
Lipinski Rule Of 5 True
Esol -3.5246971999999994
Inchi InChI=1S/C12H22O2/c1-2-3-4-5-6-7-8-9-10-11-12(13)14/h10-11H,2-9H2,1H3,(H,13,14)/b11-10+
Smiles CCCCCCCCC/C=C/C(=O)O
Nring 0.0
Np Classifier Biosynthetic Pathway Fatty acids
Defined Bond Stereocenter Count 1.0
Egan Rule True
Np Classifier Superclass Fatty Acids and Conjugates

  • 1. Outgoing r'ship FOUND_IN to/from Angelica Sinensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Areca Catechu (Plant) Rel Props:Reference:ISBN:9788172362140
  • 3. Outgoing r'ship FOUND_IN to/from Coriandrum Sativum (Plant) Rel Props:Reference:https://doi.org/10.1080/0972060x.2018.1470943
  • 4. Outgoing r'ship FOUND_IN to/from Dolichos Lablab (Plant) Rel Props:Source_db:npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Eryngium Foetidum (Plant) Rel Props:Reference:https://doi.org/10.15482/usda.adc/1239279
  • 6. Outgoing r'ship FOUND_IN to/from Ziziphus Jujuba (Plant) Rel Props:Reference:https://doi.org/10.1080/10412905.1996.9700625