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Riddelliine

PubChem CID: 5281744

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Compound Synonyms Riddelline, Riddelliine, 23246-96-0, Riddeliin, Riddeline, Riddeliine, CCRIS 4712, 18-Hydroxyseneciphylline, HSDB 7147, UNII-81YO8GX9J8, 13,19-Didehydro-12,18-dihydroxysenecionan-11,16-dione, RIDDELLINE [HSDB], Riddelliin, 81YO8GX9J8, [1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-(hydroxymethyl)-5-methylene-, (3Z,6S,14aR,14bR)-, DTXSID4026006, CHEBI:63924, Senecionan-11,16-dione, 13,19-didehydro-12,18-dihydroxy-, (15Z)-12,18-dihydroxy-13,19-didehydrosenecionan-11,16-dione, (1R,4Z,7S,17R)-4-ethylidene-7-hydroxy-7-(hydroxymethyl)-6-methylidene-2,9-dioxa-14-azatricyclo[9.5.1.014,17]heptadec-11-ene-3,8-dione, C18H23NO6, (1,6)Dioxacyclododecino(2,3,4-gh)pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-(hydroxymethyl)-5-methylene-, (3Z,6S,14aR,14bR)-, (1,6)DIOXACYCLODODECINO(2,3,4-GH)PYRROLIZINE-2,7-DIONE, 3-ETHYLIDENE-3,4,5,6,9,11,13,14,14A,14B-DECAHYDRO-6-HYDROXY-6-(HYDROXYMETHYL)-5-METHYLENE-, (6S-(3Z,6R*,14AS*,14BS*))-, (6S,9a1R,14aR,Z)-3-ethylidene-6-hydroxy-6-(hydroxymethyl)-5-methylene-3,4,5,6,9,9a1,11,13,14,14a-decahydro-[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, stereoisomer of 3-ethylidene-3,4,5,6,9,11,13,14,14alpha,14beta-decahydro-6-hydroxy-6-(hydroxymethyl)-5-methylene(1,6)dioxacyclododecino[2,3,4-gh]-pyrrolizidine-2,7-dione, (1R,4Z,7S,17R)-4-ethylidene-7-hydroxy-7-(hydroxymethyl)-6-methylidene-2,9-dioxa-14-azatricyclo(9.5.1.014,17)heptadec-11-ene-3,8-dione, [1,6]DIOXACYCLODODECINO[2,3,4-GH]PYRROLIZINE-2,7-DIONE, 3-ETHYLIDENE-3,4,5,6,9,11,13,14,14A,14B-DECAHYDRO-6-HYDROXY-6-(HYDROXYMETHYL)-5-METHYLENE-, [6S-(3Z,6R*,14AS*,14BS*)]-, STEREOISOMER OF 3-ETHYLIDENE-3,4,5,6,9,11,13,14,14ALPHA,14BETA-DECAHYDRO-6-HYDROXY-6-(HYDROXYMETHYL)-5-METHYLENE(1,6)DIOXACYCLODODECINO(2,3,4-GH)-PYRROLIZIDINE-2,7-DIONE, UN1544, DTXCID006006, SCHEMBL20771236, Riddeliin\, Riddeliine\, Riddelliine, AKOS040762283, FS-6752, trans-15-ethylidene-12beta-hydroxy-12alpha-hydroxymethyl-13-methylenesenec-1-enine, DA-57441, 1ST164452, HY-122099, CS-0081774, NS00094708, 13,19Didehydro12,18dihydroxysenecionan11,16dione, Q3935171, Senecionan11,16dione, 13,19didehydro12,18dihydroxy, (Z)-ethylidene-hydroxy-(hydroxymethyl)-methylene-[?]dione, Senecionan11,16dione, 13,19didehydro12,18dihydroxy (9CI), (1,6)DIOXACYCLODODECINO(2,3,4-GH)PYRROLIZINE-2,7-DIONE, 3- ETHYLIDENE-3,4,5,6,9,11,13,14,14A,14B-DECAHYDRO-6-HYDROXY-6- (HYDROXYMETHYL)-5-METHYLENE-, (3Z,6S,14AR,14BR)-, (1,6)Dioxacyclododecino(2,3,4gh)pyrrolizine2,7dione, 3ethylidene3,4,5,6,9,11,13,14,14a,14bdecahydro6hydroxy6(hydroxymethyl)5methylene, (3Z,6S,14aR,14bR)
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 96.3
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CCC2CCC3CCC(CC(C)C(C)CC(C)C1)C23
Np Classifier Class Pyrrolizidine alkaloids
Deep Smiles C/C=C/CC=C)[C@]O)CO))C=O)OCC=CCN[C@H]5[C@H]OC/%15=O)))CC5
Heavy Atom Count 25.0
Scaffold Graph Node Level CC1CC(O)OCC2CCN3CCC(OC(O)C(C)C1)C23
Isotope Atom Count 0.0
Molecular Complexity 666.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 3.0
Iupac Name (1R,4Z,7S,17R)-4-ethylidene-7-hydroxy-7-(hydroxymethyl)-6-methylidene-2,9-dioxa-14-azatricyclo[9.5.1.014,17]heptadec-11-ene-3,8-dione
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 0.2
Gsk 4 400 Rule True
Molecular Formula C18H23NO6
Scaffold Graph Node Bond Level C=C1CC(=C)C(=O)OC2CCN3CC=C(COC(=O)C1)C23
Inchi Key SVCNNZDUGWLODJ-RAYFHMIRSA-N
Silicos It Class Soluble
Rotatable Bond Count 1.0
Synonyms riddeline, riddelliine, riddelline
Esol Class Soluble
Functional Groups C/C=C(/C)C(=O)OC, C=C(C)C, CC=C(C)C, CN(C)C, CO, COC(C)=O
Compound Name Riddelliine
Exact Mass 349.153
Formal Charge 0.0
Monoisotopic Mass 349.153
Hydrogen Bond Acceptor Count 7.0
Molecular Weight 349.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 3.0
Total Bond Stereocenter Count 1.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C18H23NO6/c1-3-12-8-11(2)18(23,10-20)17(22)24-9-13-4-6-19-7-5-14(15(13)19)25-16(12)21/h3-4,14-15,20,23H,2,5-10H2,1H3/b12-3-/t14-,15-,18-/m1/s1
Smiles C/C=C\1/CC(=C)[C@@](C(=O)OCC2=CCN3[C@H]2[C@@H](CC3)OC1=O)(CO)O
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 1.0
Egan Rule True
Np Classifier Superclass Ornithine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Crotalaria Juncea (Plant) Rel Props:Reference:https://doi.org/10.15482/usda.adc/1239279
  • 2. Outgoing r'ship FOUND_IN to/from Senecio Vulgaris (Plant) Rel Props:Reference:ISBN:9788172363093