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Anacrotine

PubChem CID: 5281720

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Compound Synonyms Anacrotine, 5096-49-1, Crotalaburnine, WS4XLD79SV, NSC 114571, BRN 1090468, (1S,4Z,6R,7R,16R,17R)-4-ethylidene-7,16-dihydroxy-6,7-dimethyl-2,9-dioxa-14-azatricyclo[9.5.1.014,17]heptadec-11-ene-3,8-dione, Senecionan-11,16-dione, 6,12-dihydroxy-, (6-beta)-, NSC-114571, (+)-Anacrotine, UNII-WS4XLD79SV, (1,6)Dioxacyclododecino(2,3-gh)pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6,14-dihydroxy-5,6-dimethyl-, (3Z,5R,6R,14R,14aS,14bR)-, CHEBI:2697, DTXSID801317393, AKOS040734819, FS-6727, Q27105769, (3Z,5R,6R,14R,14aS,14bR)-3-Ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6,14-dihydroxy-5,6-dimethyl[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, [1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6,14-dihydroxy-5,6-dimethyl-, (3Z,5R,6R,14R,14aS,14bR)-
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 96.3
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CCCC(C)C(C)CC2CCC3CCC(CC1)C32
Np Classifier Class Pyrrolizidine alkaloids
Deep Smiles C/C=C/C[C@@H]C)[C@@]C)O)C=O)OCC=CCN[C@H]5[C@H]OC/%15=O)))[C@H]O)C5
Heavy Atom Count 25.0
Classyfire Class Macrolides and analogues
Scaffold Graph Node Level CC1CCCC(O)OCC2CCN3CCC(OC1O)C23
Isotope Atom Count 0.0
Molecular Complexity 641.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 5.0
Iupac Name (1S,4Z,6R,7R,16R,17R)-4-ethylidene-7,16-dihydroxy-6,7-dimethyl-2,9-dioxa-14-azatricyclo[9.5.1.014,17]heptadec-11-ene-3,8-dione
Veber Rule True
Classyfire Superclass Phenylpropanoids and polyketides
Xlogp 0.1
Gsk 4 400 Rule True
Molecular Formula C18H25NO6
Scaffold Graph Node Bond Level C=C1CCCC(=O)OCC2=CCN3CCC(OC1=O)C23
Inchi Key NPYPUYCITBTPSF-TZCAYXSXSA-N
Silicos It Class Soluble
Rotatable Bond Count 0.0
Synonyms anacrotine, crotalaburnine
Esol Class Soluble
Functional Groups C/C=C(/C)C(=O)OC, CC=C(C)C, CN(C)C, CO, COC(C)=O
Compound Name Anacrotine
Exact Mass 351.168
Formal Charge 0.0
Monoisotopic Mass 351.168
Hydrogen Bond Acceptor Count 7.0
Molecular Weight 351.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 5.0
Total Bond Stereocenter Count 1.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C18H25NO6/c1-4-11-7-10(2)18(3,23)17(22)24-9-12-5-6-19-8-13(20)15(14(12)19)25-16(11)21/h4-5,10,13-15,20,23H,6-9H2,1-3H3/b11-4-/t10-,13-,14-,15-,18-/m1/s1
Smiles C/C=C\1/C[C@H]([C@@](C(=O)OCC2=CCN3[C@H]2[C@@H]([C@@H](C3)O)OC1=O)(C)O)C
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 1.0
Egan Rule True
Np Classifier Superclass Ornithine alkaloids

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