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Rhamnetin

PubChem CID: 5281691

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Compound Synonyms Rhamnetin, 90-19-7, beta-Rhamnocitrin, 7-Methoxyquercetin, 7-O-Methylquercetin, 7-Methylquercetin, Quercetin 7-methyl ether, 7-O-Methyl Quercetin, 3,5,3',4'-Tetrahydroxy-7-methoxyflavone, .beta.-Rhamnocitrin, 3,3',4',5-Tetrahydroxy-7-methoxyflavone, 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-methoxy-4H-chromen-4-one, C.I. 75690, NSC 19802, 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-methoxychromen-4-one, CCRIS 3792, 2-(3,4-Dihydroxyphenyl)-3,5-dihydroxy-7-methoxy-4H-1-benzopyran-4-one, EINECS 201-974-1, NSC-19802, BRN 0047741, CHEBI:74992, 3,5,3',4'-Tetrahydroxy-7-methoxyflaone, 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-methoxy-, NSC19802, RHAMNETIN [MI], Flavone, 3,3',4',5-tetrahydroxy-7-methoxy-, 71803L5F4S, FLAVONE, 7-METHOXY-3,3',4',5-TETRAHYDROXY-, CHEMBL312163, DTXSID40237979, 5-18-05-00495 (Beilstein Handbook Reference), MFCD00016931, 7-methoxy-quercetin, UNII-71803L5F4S, Rhamnetin (Standard), Spectrum_001185, SpecPlus_000463, 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-methoxy-chromen-4-one, Spectrum2_000642, Spectrum3_001343, Spectrum4_001872, Spectrum5_000464, BSPBio_003125, KBioGR_002367, KBioSS_001665, SPECTRUM310031, DivK1c_006559, Rhamnetin, analytical standard, SCHEMBL555118, SPBio_000643, BDBM23410, HY-N7036R, KBio1_001503, KBio2_001665, KBio2_004233, KBio2_006801, KBio3_002345, DTXCID40160470, Rhamnetin - Tech grade ca 50%, 2-(3,4-Dihydroxy-phenyl)-3,5-dihydroxy-7-methoxy-chromen-4-one, HY-N7036, CCG-38555, LMPK12112624, AKOS027320587, 3,4',5-Tetrahydroxy-7-methoxyflavone, CS-W014522, FM25558, SDCCGMLS-0066624.P001, NCGC00095624-01, NCGC00095624-02, NCGC00095624-03, NCGC00178254-01, AS-78315, DA-51073, NCI60_001648, Flavone,3',4',5-tetrahydroxy-7-methoxy-, NS00015848, E87178, Q288988, SR-05000002269, SR-05000002269-2, BRD-K37206356-001-01-3, Flavone, 3,3',4',5-tetrahydroxy-7-methoxy-(8CI), 4H-1-Benzopyran-4-one,4-dihydroxyphenyl)-3,5-dihydroxy-7-methoxy-, 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-methoxy-(9CI), 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-y-methoxy-4H-1-benzopyran-4-one, Rhamnetin, 3,3',4',5-Tetrahydroxy-7-methoxyflavone, 201-974-1, J8G
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 116.0
Hydrogen Bond Donor Count 4.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CC(C2CCCCC2)CC2CCCCC12
Np Classifier Class Flavonols
Deep Smiles COcccO)ccc6)occc6=O))O))cccccc6)O))O
Heavy Atom Count 23.0
Classyfire Class Flavonoids
Description 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-methoxy-4h-chromen-4-one, also known as 7-methoxyquercetin or quercetin 7-methyl ether, is a member of the class of compounds known as flavonols. Flavonols are compounds that contain a flavone (2-phenyl-1-benzopyran-4-one) backbone carrying a hydroxyl group at the 3-position. Thus, 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-methoxy-4h-chromen-4-one is considered to be a flavonoid lipid molecule. 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-methoxy-4h-chromen-4-one is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-methoxy-4h-chromen-4-one can be found in a number of food items such as tea, apple, sweet orange, and parsley, which makes 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-methoxy-4h-chromen-4-one a potential biomarker for the consumption of these food products.
Scaffold Graph Node Level OC1CC(C2CCCCC2)OC2CCCCC12
Classyfire Subclass Flavones
Isotope Atom Count 0.0
Molecular Complexity 503.0
Database Name cmaup_ingredients;fooddb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id Q7ZJM1, P04745, n.a., Q03164, P02545, P46063, Q99714, B2RXH2, Q9NUW8, P10636, P25779, P10828, P51450, P08684, O15296, Q9UBT6, P15121, Q28731, O42275, P81908, Q86831, Q9NPD5, Q9Y6L6, P53778, P45983, Q91Y86, Q63844, Q9Z1B7, P27695, P00690, Q14576, Q9UHH9, Q8NFU5
Iupac Name 2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-7-methoxychromen-4-one
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Phenylpropanoids and polyketides
Target Id NPT483, NPT47, NPT149, NPT48, NPT50, NPT51, NPT46, NPT109, NPT41
Xlogp 1.9
Gsk 4 400 Rule True
Molecular Formula C16H12O7
Scaffold Graph Node Bond Level O=c1cc(-c2ccccc2)oc2ccccc12
Prediction Swissadme 0.0
Inchi Key JGUZGNYPMHHYRK-UHFFFAOYSA-N
Silicos It Class Soluble
Fcsp3 0.0625
Logs -3.712
Rotatable Bond Count 2.0
Logd 2.334
Synonyms 2-(3,4-Dihydroxyphenyl)-3,5-dihydroxy-7-methoxy-4H-1-benzopyran-4-one, 9CI, 3',4',5-Trihydroxy-7-methoxyflavonol, b-Rhamnocitrin, Quercetin 7-methyl ether, Rhamnetin, rhamnetin
Esol Class Soluble
Functional Groups c=O, cO, cOC, coc
Compound Name Rhamnetin
Prediction Hob Swissadme 0.0
Exact Mass 316.058
Formal Charge 0.0
Monoisotopic Mass 316.058
Hydrogen Bond Acceptor Count 7.0
Molecular Weight 316.26
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -3.386925608695652
Inchi InChI=1S/C16H12O7/c1-22-8-5-11(19)13-12(6-8)23-16(15(21)14(13)20)7-2-3-9(17)10(18)4-7/h2-6,17-19,21H,1H3
Smiles COC1=CC(=C2C(=C1)OC(=C(C2=O)O)C3=CC(=C(C=C3)O)O)O
Nring 3.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Flavonoids

  • 1. Outgoing r'ship FOUND_IN to/from Aconitum Sajanense (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Ajania Fruticulosa (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Albizia Julibrissin (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Ammannia Multiflora (Plant) Rel Props:Reference:ISBN:9788185042114
  • 5. Outgoing r'ship FOUND_IN to/from Ammi Visnaga (Plant) Rel Props:Reference:ISBN:9788185042145
  • 6. Outgoing r'ship FOUND_IN to/from Annona Glabra (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 7. Outgoing r'ship FOUND_IN to/from Annona Muricata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 8. Outgoing r'ship FOUND_IN to/from Anodendron Affine (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 9. Outgoing r'ship FOUND_IN to/from Antigonon Leptopus (Plant) Rel Props:Reference:ISBN:9770972795006; ISBN:9788185042114
  • 10. Outgoing r'ship FOUND_IN to/from Artemisia Annua (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 11. Outgoing r'ship FOUND_IN to/from Artemisia Dracunculus (Plant) Rel Props:Source_db:fooddb_chem_all
  • 12. Outgoing r'ship FOUND_IN to/from Artemisia Jacutica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 13. Outgoing r'ship FOUND_IN to/from Astragalus Curvicarpus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 14. Outgoing r'ship FOUND_IN to/from Avrainvillea Rawsonii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 15. Outgoing r'ship FOUND_IN to/from Bersama Abyssinica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 16. Outgoing r'ship FOUND_IN to/from Biancaea Sappan (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 17. Outgoing r'ship FOUND_IN to/from Bistorta Manshuriensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 18. Outgoing r'ship FOUND_IN to/from Bistorta Officinalis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 19. Outgoing r'ship FOUND_IN to/from Boehmeria Pannosa (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 20. Outgoing r'ship FOUND_IN to/from Caesalpinia Sappan (Plant) Rel Props:Reference:https://www.ncbi.nlm.nih.gov/pubmed/19148862
  • 21. Outgoing r'ship FOUND_IN to/from Capparis Grandis (Plant) Rel Props:Reference:ISBN:9770972795006
  • 22. Outgoing r'ship FOUND_IN to/from Capparis Sepiaria (Plant) Rel Props:Reference:ISBN:9770972795006
  • 23. Outgoing r'ship FOUND_IN to/from Cassia Jahnii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 24. Outgoing r'ship FOUND_IN to/from Cedrela Salvadorensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 25. Outgoing r'ship FOUND_IN to/from Cirsium Carolinianum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 26. Outgoing r'ship FOUND_IN to/from Coptis Chinensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 27. Outgoing r'ship FOUND_IN to/from Coptis Deltoidea (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 28. Outgoing r'ship FOUND_IN to/from Coptis Japonica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 29. Outgoing r'ship FOUND_IN to/from Coptis Teeta (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 30. Outgoing r'ship FOUND_IN to/from Coriandrum Sativum (Plant) Rel Props:Source_db:fooddb_chem_all
  • 31. Outgoing r'ship FOUND_IN to/from Crocus Sativus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 32. Outgoing r'ship FOUND_IN to/from Damnacanthus Major (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 33. Outgoing r'ship FOUND_IN to/from Derris Trifoliata (Plant) Rel Props:Reference:ISBN:9788172363178
  • 34. Outgoing r'ship FOUND_IN to/from Dipentodon Sinicus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 35. Outgoing r'ship FOUND_IN to/from Erigeron Canadensis (Plant) Rel Props:Reference:https://www.ncbi.nlm.nih.gov/pubmed/2179716
  • 36. Outgoing r'ship FOUND_IN to/from Erysimum Cheiri (Plant) Rel Props:Reference:ISBN:9780387706375
  • 37. Outgoing r'ship FOUND_IN to/from Eucalyptus Radiata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 38. Outgoing r'ship FOUND_IN to/from Eugenia Caryopyhllata (Plant) Rel Props:Source_db:npass_chem_all
  • 39. Outgoing r'ship FOUND_IN to/from Fraxinus Ornus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 40. Outgoing r'ship FOUND_IN to/from Garcinia Cambogia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 41. Outgoing r'ship FOUND_IN to/from Hertia Cheirifolia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 42. Outgoing r'ship FOUND_IN to/from Hypericum Oblongifolium (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 43. Outgoing r'ship FOUND_IN to/from Ilex Taubertiana (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 44. Outgoing r'ship FOUND_IN to/from Licaria Chrysophylla (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 45. Outgoing r'ship FOUND_IN to/from Menyanthes Trifoliata (Plant) Rel Props:Reference:ISBN:9788172361150
  • 46. Outgoing r'ship FOUND_IN to/from Moringa Pterygosperma (Plant) Rel Props:Reference:ISBN:9770972795006
  • 47. Outgoing r'ship FOUND_IN to/from Mussaenda Philippica (Plant) Rel Props:Reference:ISBN:9770972795006
  • 48. Outgoing r'ship FOUND_IN to/from Nervilia Fordii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 49. Outgoing r'ship FOUND_IN to/from Ormosia Hosiei (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 50. Outgoing r'ship FOUND_IN to/from Ornithoglossum Viride (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 51. Outgoing r'ship FOUND_IN to/from Pelargonium Roseum (Plant) Rel Props:Source_db:npass_chem_all
  • 52. Outgoing r'ship FOUND_IN to/from Peltophorum Pterocarpum (Plant) Rel Props:Reference:ISBN:9789327275590
  • 53. Outgoing r'ship FOUND_IN to/from Pericome Caudata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 54. Outgoing r'ship FOUND_IN to/from Persicaria Glabra (Plant) Rel Props:Reference:ISBN:9780387706375
  • 55. Outgoing r'ship FOUND_IN to/from Persicaria Pulchra (Plant) Rel Props:Reference:ISBN:9788185042084
  • 56. Outgoing r'ship FOUND_IN to/from Petasites Laevigatus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 57. Outgoing r'ship FOUND_IN to/from Piper Attenuatum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 58. Outgoing r'ship FOUND_IN to/from Piper Lanceifolium (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 59. Outgoing r'ship FOUND_IN to/from Piper Nigrum (Plant) Rel Props:Source_db:fooddb_chem_all
  • 60. Outgoing r'ship FOUND_IN to/from Pogostemon Cablin (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 61. Outgoing r'ship FOUND_IN to/from Populus Nigra (Plant) Rel Props:Reference:ISBN:9788185042084
  • 62. Outgoing r'ship FOUND_IN to/from Rhamnus Napalensis (Plant) Rel Props:Reference:ISBN:9788185042084
  • 63. Outgoing r'ship FOUND_IN to/from Rubia Tetragona (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 64. Outgoing r'ship FOUND_IN to/from Rubus Sanctus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 65. Outgoing r'ship FOUND_IN to/from Schizanthus Tricolor (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 66. Outgoing r'ship FOUND_IN to/from Sesamum Indicum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 67. Outgoing r'ship FOUND_IN to/from Sigesbeckia Glabrescens (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 68. Outgoing r'ship FOUND_IN to/from Sigesbeckia Pubescens (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 69. Outgoing r'ship FOUND_IN to/from Solidago Virgaurea (Plant) Rel Props:Reference:ISBN:9788185042138
  • 70. Outgoing r'ship FOUND_IN to/from Sonchus Oleraceus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 71. Outgoing r'ship FOUND_IN to/from Sphaeranthus Confertifolius (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 72. Outgoing r'ship FOUND_IN to/from Spinulum Annotinum (Plant) Rel Props:Source_db:npass_chem_all
  • 73. Outgoing r'ship FOUND_IN to/from Stauntonia Hexaphylla (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 74. Outgoing r'ship FOUND_IN to/from Strychnos Triplinervia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 75. Outgoing r'ship FOUND_IN to/from Syzygium Aromaticum (Plant) Rel Props:Source_db:cmaup_ingredients;fooddb_chem_all;npass_chem_all
  • 76. Outgoing r'ship FOUND_IN to/from Tamarix Aphylla (Plant) Rel Props:Reference:ISBN:9788185042084
  • 77. Outgoing r'ship FOUND_IN to/from Ziziphus Jujuba (Plant) Rel Props:Reference:ISBN:9788172360818