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Harmine

PubChem CID: 5280953

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Compound Synonyms HARMINE, 442-51-3, 7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole, Banisterine, Telepathine, Leucoharmine, Yageine, Yajeine, 9H-Pyrido[3,4-b]indole, 7-methoxy-1-methyl-, 7-Methoxy-1-methyl-9H-beta-carboline, Banisterin, Telepathin, Harmin, Yagein, 7-Methoxy-1-methyl-9H-pyrido(3,4-b)indole, 1-Methyl-7-methoxy-beta-carboline, Harmine (Telepathine), MFCD00004958, EINECS 207-131-4, UNII-4FHH5G48T7, Harmin hydrochloride, 9H-Pyrido(3,4-b)indole, 7-methoxy-1-methyl-, BRN 0178813, 4FHH5G48T7, CHEBI:28121, HARMINE [MI], HARMINE [MART.], DTXSID30196066, 5-23-12-00237 (Beilstein Handbook Reference), 1-Methyl-7-methoxy-.beta.-carboline, HARMINE (MART.), Garmin, MLS002153910, HRM, SR-05000001527, SMR001233259, Telepathien, 7-methoxy-1-methylbeta-carboline, 3anr, 1,4-Benzenedicarboxylic Acid Mono(phenylmethyl) Ester, Terephthalic Acid Benzyl Ester, Terephthalic Acid Monobenzyl Ester, Monobenzyl 1,4-Benzenedicarboxylate, Monobenzyl Terephthalate, p-(Benzyloxycarbonyl)benzoic Acid, Harmine (Standard), Harmine, 98%, Spectrum_001128, SpecPlus_000611, Prestwick0_000613, Prestwick1_000613, Prestwick2_000613, Prestwick3_000613, Spectrum2_000568, Spectrum3_000906, Spectrum4_001004, Spectrum5_001914, Oprea1_596686, BSPBio_000546, KBioGR_001467, KBioSS_001608, BIDD:ER0478, BIDD:GT0106, DivK1c_006707, SCHEMBL292955, SPECTRUM1500867, SPBio_000356, SPBio_002765, BPBio1_000602, CHEMBL269538, GTPL9352, HY-N0737AR, MEGxp0_001875, CHEMBL4095474, ACon0_001194, ACon1_000061, cid_5359389, HY-N0737A, KBio1_001651, KBio2_001608, KBio2_004176, KBio2_006744, KBio3_001852, DTXCID40118557, BDBM100152, HMS1921M06, HMS2090H04, HMS3561B11, HMS3650H03, HMS3885E10, 1-Methyl-7-methoxy-beta -carboline, CCG-38734, s3868, STK047386, AKOS003673313, 442-51-3 (FREE BASE), CS-5325, DB07919, FH23740, SDCCGMLS-0066733.P001, NCGC00016435-01, NCGC00016435-02, NCGC00016435-03, NCGC00016435-04, NCGC00016435-05, NCGC00016435-06, NCGC00016435-07, NCGC00016435-09, NCGC00016435-20, NCGC00094869-01, NCGC00094869-02, NCGC00094869-03, NCGC00094869-04, NCGC00094869-05, NCGC00094869-06, 1ST40316, 7-Methoxy-1-methyl-9H-beta-carboline #, AC-31456, AS-13970, BP-30211, CAS-343-27-1, SY062283, DB-051199, AB00052850, H0001, NS00015429, C06538, H-1200, AB00052850-08, Q128381, 7-methoxy-1-methyl-9H-beta-carboline, hydrochloride, 7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole, 9CI, A1-03319, SR-05000001527-1, SR-05000001527-4, SR-05000001527-5, SR-05000001527-8, BRD-K30984264-001-01-3, BRD-K30984264-001-04-7, BRD-K30984264-001-05-4, BRD-K30984264-003-03-5, BRD-K30984264-003-06-8, 7-METHOXY-1-METHYL-9H-PYRIDO[3,4-B]INDOL, HARMINE, 7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole, 1-Methyl-7-methoxy-b-carboline, 122992-92-1, 207-131-4
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 37.9
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CC1CCCCC12
Np Classifier Class Carboline alkaloids
Deep Smiles COcccccc6)[nH]cc5ccnc6C
Heavy Atom Count 16.0
Classyfire Class Harmala alkaloids
Scaffold Graph Node Level C1CCC2C(C1)NC1CNCCC12
Isotope Atom Count 0.0
Molecular Complexity 258.0
Database Name cmaup_ingredients;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id P47898, P10635, P08908, P28222, P28221, P14842, P28335, Q8WXA8, P50406, P34969, P21728, Q9ES14, P23385, P08912, P35348, P35368, P08913, P18089, P18825, P08588, P07550, P31645, P23975, P27922, Q9Y2I1, Q00535, P24941, O95067, P78396, Q15078, Q04759, P06239, P07948, P06241, P17405, P28593, O75116, Q15418, Q15759, O15264, P53778, O96013, Q9P286, Q9NQU5, O15530, P11309, Q9P1W9, Q86V86, P17612, P31749, P31751, P17252, Q05513, Q15139, Q96SB4, P51812, P23443, O00141, Q15746, P00523, P48730, Q13627, Q92630, O43781, Q96GD4, Q9UQB9, Q8IWQ3, Q14012, Q8N5S9, Q96RR4, O14757, O96017, P19784, P41240, O00418, P27361, P28482, Q8TD08, Q13188, P51955, Q9HC98, Q8TDX7, Q16539, P49841, Q9H2X6, Q9H422, O14920, P45984, P53779, P06240, P49137, Q16644, P45983, P27448, Q14680, Q02750, Q9BUB5, Q9HBH9, O75582, P53350, Q8IW41, Q16513, P21397, n.a., Q99714, B2RXH2, Q16637, P25779, P51450, P00352, Q16665, P15428, P08684, P27338, Q16236, Q92830, O15296, Q9HAZ1, P05177, P83916, P39748, P49759, P84022, O89049, Q8TF76, O42275, P22303, Q99700, I6LNT8, P49840, P63086, Q9NR20, Q9Y463, Q63470, O35493, O35492, O35491, P50750, P50613, P22518, Q9NUW8, Q9Y6L6, Q9NPD5, P27695, Q25615, Q969S8, P49674, P20248, Q9BWU1, P49336, O76039, O14578, P49760, P48729, P78368, P68400, P53355, Q9UIK4, O43293, O94768, Q86Z02, P51617, Q9Y616, Q9UBF8, Q8TBX8, O75676, P37173, Q8NEB9, Q13547, P28223, P48736, Q9UNQ0
Iupac Name 7-methoxy-1-methyl-9H-pyrido[3,4-b]indole
Prediction Hob 1.0
Class Harmala alkaloids
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Target Id NPT110, NPT292, NPT294, NPT1785, NPT222, NPT223, NPT224, NPT228, NPT1791, NPT3266, NPT3114, NPT3399, NPT3460, NPT1701, NPT261, NPT149, NPT48, NPT93, NPT94, NPT211, NPT151, NPT109, NPT582, NPT208, NPT1681, NPT4093, NPT3459, NPT3274, NPT1422
Xlogp 3.6
Superclass Alkaloids and derivatives
Gsk 4 400 Rule True
Molecular Formula C13H12N2O
Scaffold Graph Node Bond Level c1ccc2c(c1)[nH]c1cnccc12
Prediction Swissadme 0.0
Inchi Key BXNJHAXVSOCGBA-UHFFFAOYSA-N
Silicos It Class Moderately soluble
Fcsp3 0.1538461538461538
Logs -2.777
Rotatable Bond Count 1.0
State Solid
Logd 2.765
Synonyms 6-Methoxyharman, 7-Methoxy-1-methyl-9H-beta-carboline, Banisterine, Leucoharmine, Telepathine, Yageine, Yajeine, 7-Methoxy-1-methyl-9H-b-carboline, 7-Methoxy-1-methyl-9H-β-carboline, 1-Methyl-7-methoxy-beta -carboline, 1-Methyl-7-methoxy-beta-carboline, 442-51-3 (FREE base), 7-Methoxy-1-methyl-9H-pyrido(3,4-b)indole, 7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole, 7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole, 9ci, Banisterin, Garmin, Harmin, Harmin hydrochloride, HRM, Telepathien, Telepathin, Yagein, harminc, harmine
Esol Class Moderately soluble
Functional Groups cOC, c[nH]c, cnc
Compound Name Harmine
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 212.095
Formal Charge 0.0
Monoisotopic Mass 212.095
Hydrogen Bond Acceptor Count 2.0
Molecular Weight 212.25
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aromatic heteropolycyclic compounds
Lipinski Rule Of 5 True
Esol -4.047412400000001
Inchi InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3
Smiles CC1=NC=CC2=C1NC3=C2C=CC(=C3)OC
Nring 3.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Taxonomy Direct Parent Harmala alkaloids
Np Classifier Superclass Tryptophan alkaloids

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