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4,21-Dehydrogeissoschizine

PubChem CID: 5280619

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Compound Synonyms 4,21-Dehydrogeissoschizine, 73385-56-5, 4,21-Dehydro-16E,19E-geissoschizine, Z3D2Q8C832, UNII-Z3D2Q8C832, methyl (Z)-2-[(2S,3E,12bS)-3-ethylidene-1,2,6,7,12,12b-hexahydroindolo[2,3-a]quinolizin-5-ium-2-yl]-3-hydroxyprop-2-enoate, CHEBI:17294, Corynanium, 4,16,17,19,20,21-hexadehydro-17-hydroxy-16-(methoxycarbonyl)-, (16E,19E)-, methyl (19E)-16-(hydroxymethylidene)-4,21-didehydrocoryn-19-en-4-ium-17-oate, methyl (19E)-16-(hydroxymethylidene)coryna-4(21),19-dien-4-ium-17-oate, 1H-Indolo(2,3-a)quinolizin-5-ium, 3-ethylidene-2,3,6,7,12,12b-hexahydro-2-(1-(hydroxymethylene)-2-methoxy-2-oxoethyl)-, (2S-(2alpha(E),3E,12bbeta))-, 1H-INDOLO(2,3-A)QUINOLIZIN-5-IUM, 3-ETHYLIDENE-2,3,6,7,12,12B-HEXAHYDRO-2-(1-(HYDROXYMETHYLENE)-2-METHOXY-2-OXOETHYL)-, (2S-(2.ALPHA.(E),3E,12B.BETA.))-, 1H-Indolo[2,3-a]quinolizin-5-ium, 3-ethylidene-2,3,6,7,12,12b-hexahydro-2-[1-(hydroxymethylene)-2-methoxy-2-oxoethyl]-, [2S-[2alpha(E),3E,12bbeta]]-, methyl (Z)-2-((2S,3E,12bS)-3-ethylidene-1,2,6,7,12,12b-hexahydroindolo(2,3-a)quinolizin-5-ium-2-yl)-3-hydroxyprop-2-enoate, methyl 2-((2S,3E,12bS)-3-ethylidene-1,2,6,7,12,12b-hexahydroindolo(2,3-a)quinolizin-5-ium-2-yl)-3-hydroxyprop-2-enoate, methyl 2-[(2S,3E,12bS)-3-ethylidene-1,2,6,7,12,12b-hexahydroindolo[2,3-a]quinolizin-5-ium-2-yl]-3-hydroxyprop-2-enoate, C03677, SCHEMBL23658250, DTXSID90415063, Q19596766
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 65.3
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CCC2C(CCC3C4CCCCC4CC23)C1
Np Classifier Class Corynanthe type
Deep Smiles COC=O)/C=CO))/[C@H]C[C@@H][N+]=C/C/6=C/C))))CCcc6[nH]cc5cccc6
Heavy Atom Count 26.0
Classyfire Class Indoles and derivatives
Scaffold Graph Node Level CC1CCC2C3NC4CCCCC4C3CCN2C1
Classyfire Subclass Pyridoindoles
Isotope Atom Count 0.0
Molecular Complexity 666.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 2.0
Iupac Name methyl (Z)-2-[(2S,3E,12bS)-3-ethylidene-1,2,6,7,12,12b-hexahydroindolo[2,3-a]quinolizin-5-ium-2-yl]-3-hydroxyprop-2-enoate
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 2.7
Gsk 4 400 Rule True
Molecular Formula C21H23N2O3+
Scaffold Graph Node Bond Level C=C1C=[N+]2CCc3c([nH]c4ccccc34)C2CC1
Inchi Key CUHFIPBCFIPFJM-JXSBNBLESA-O
Silicos It Class Moderately soluble
Rotatable Bond Count 3.0
Synonyms 4,21-dehydrogeissoschizine
Esol Class Soluble
Functional Groups C/C=C(C)C=[N+](C)C, COC(=O)/C(C)=CO, c[nH]c
Compound Name 4,21-Dehydrogeissoschizine
Exact Mass 351.171
Formal Charge 1.0
Monoisotopic Mass 351.171
Hydrogen Bond Acceptor Count 3.0
Molecular Weight 351.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 2.0
Total Bond Stereocenter Count 2.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C21H22N2O3/c1-3-13-11-23-9-8-15-14-6-4-5-7-18(14)22-20(15)19(23)10-16(13)17(12-24)21(25)26-2/h3-7,11-12,16,19,22H,8-10H2,1-2H3/p+1/b13-3-/t16-,19-/m0/s1
Smiles C/C=C\1/C=[N+]2CCC3=C([C@@H]2C[C@@H]1/C(=C/O)/C(=O)OC)NC4=CC=CC=C34
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 2.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Catharanthus Roseus (Plant) Rel Props:Reference:https://doi.org/10.1093/database/bav075