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Fraxin

PubChem CID: 5273568

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Compound Synonyms Fraxin, 524-30-1, Fraxetin-8-O-glucoside, Fraxoside, FRAXINE, EINECS 208-355-5, FRAXIN [MI], V7M270Y072, FRAXETOL 8-GLUCOSIDE, 2H-1-Benzopyran-2-one, 8-(beta-D-glucopyranosyloxy)-7-hydroxy-6-methoxy-, CHEBI:5170, fraxetin-8-O-beta-D-glucoside, DTXSID30200410, fraxetin-8-beta-D-glucopyranoside, fraxetin-8-O-beta-D-glucopyranoside, MFCD00010093, FRAXETIN 8-.BETA.-D-GLUCOPYRANOSIDE, 8-(beta-D-Glucopyranosyloxy)-7-hydroxy-6-methoxy-2H-1-benzopyran-2-one, 2H-1-Benzopyran-2-one, 8-(.beta.-D-glucopyranosyloxy)-7-hydroxy-6-methoxy-, 7-hydroxy-6-methoxy-8-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-2-one, 7,8-DIHYDROXY-6-METHOXYCOUMARIN 8-.BETA.-D-GLUCOPYRANOSIDE, 7-hydroxy-6-methoxy-2-oxo-2H-chromen-8-yl beta-D-glucopyranoside, 7-Hydroxy-6-methoxy-8-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2H-chromen-2-one, UNII-V7M270Y072, Fraxin (Standard), 7-hydroxy-6-methoxy-8-((2S,4R,5S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl)oxychromen-2-one, 7-hydroxy-6-methoxy-8-[(2S,4R,5S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-2-one, Fraxin, analytical standard, MLS002473090, 7,8-dihydroxy-6-methoxycoumarin-8-beta-D-glucoside, CHEMBL293864, MEGxp0_000484, SCHEMBL1227439, ACon1_000325, EX-A8002Y, HY-N0579R, DTXCID30122901, CRSFLLTWRCYNNX-QBNNUVSCSA-N, HMS2225L24, HY-N0579, BDBM50428429, s9296, AKOS037514646, CCG-268292, FF73926, FRAXETIN 8-BETA-D-GLUCOPYRANOSIDE, NCGC00169184-01, 7-hydroxy-6-methoxy-8-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-chromen-2-one, AC-34583, AS-77295, SMR001397192, CS-0009114, NS00032506, Q1452081, BRD-K31984062-001-01-6, 8-(beta-d-glucopyranosyloxy)-7-hydroxy-6-methoxycoumarin, 7,8-Dihydroxy-6-methoxycoumarin 8-beta-D-glucopyranoside, 2H-1-Benzopyran-2-one,8-(beta-D-glucopyranosyloxy)-7-hydroxy-6-methoxy-, 7,8-Dihydroxy-6-methoxycoumarin-beta-D-glucopyranoside hplc, Fraxetin-8-glucoside, Fraxoside, 7-hydroxy-6-methoxy-8-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-2H-chromen-2-one, InChI=1/C16H18O10/c1-23-7-4-6-2-3-9(18)25-14(6)15(11(7)20)26-16-13(22)12(21)10(19)8(5-17)24-16/h2-4,8,10,12-13,16-17,19-22H,5H2,1H3/t8-,10-,12+,13-,16+/m1/s
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 155.0
Hydrogen Bond Donor Count 5.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CCC2CCCC(CC3CCCCC3)C2C1
Np Classifier Class Simple coumarins
Deep Smiles OC[C@H]O[C@@H]OccO)cOC))ccc6oc=O)cc6)))))))))))[C@@H][C@H][C@@H]6O))O))O
Heavy Atom Count 26.0
Classyfire Class Coumarins and derivatives
Scaffold Graph Node Level OC1CCC2CCCC(OC3CCCCO3)C2O1
Classyfire Subclass Coumarin glycosides
Isotope Atom Count 0.0
Molecular Complexity 539.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 5.0
Uniprot Id Q92830, O95149, Q9UNA4, O89049, O75496, O94925, Q99700, Q8N1Q1, O43570, P00915, P43166, Q16790, P00918, O94782
Iupac Name 7-hydroxy-6-methoxy-8-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-2-one
Prediction Hob 0.0
Veber Rule False
Classyfire Superclass Phenylpropanoids and polyketides
Target Id NPT3101, NPT949, NPT947, NPT955, NPT948
Xlogp -0.6
Gsk 4 400 Rule True
Molecular Formula C16H18O10
Scaffold Graph Node Bond Level O=c1ccc2cccc(OC3CCCCO3)c2o1
Prediction Swissadme 0.0
Inchi Key CRSFLLTWRCYNNX-QBNNUVSCSA-N
Silicos It Class Soluble
Fcsp3 0.4375
Logs -1.591
Rotatable Bond Count 4.0
Logd -0.624
Synonyms fraxin
Esol Class Very soluble
Functional Groups CO, c=O, cO, cOC, cO[C@@H](C)OC, coc
Compound Name Fraxin
Prediction Hob Swissadme 0.0
Exact Mass 370.09
Formal Charge 0.0
Monoisotopic Mass 370.09
Hydrogen Bond Acceptor Count 10.0
Molecular Weight 370.31
Gi Absorption False
Covalent Unit Count 1.0
Total Atom Stereocenter Count 5.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -0.6949373846153851
Inchi InChI=1S/C16H18O10/c1-23-7-4-6-2-3-9(18)25-14(6)15(11(7)20)26-16-13(22)12(21)10(19)8(5-17)24-16/h2-4,8,10,12-13,16-17,19-22H,5H2,1H3/t8-,10-,12+,13-,16+/m1/s1
Smiles COC1=C(C(=C2C(=C1)C=CC(=O)O2)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O
Nring 3.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule False
Np Classifier Superclass Coumarins

  • 1. Outgoing r'ship FOUND_IN to/from Alchornea Cordifolia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Amomum Daniellii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Atalantia Wightii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Balanophora Japonica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Carpesium Cernuum (Plant) Rel Props:Source_db:npass_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Corydalis Persica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 7. Outgoing r'ship FOUND_IN to/from Corynanthe Pachyceras (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 8. Outgoing r'ship FOUND_IN to/from Cota Tinctoria (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 9. Outgoing r'ship FOUND_IN to/from Cynoglossum Amabile (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 10. Outgoing r'ship FOUND_IN to/from Ficus Benghalensis (Plant) Rel Props:Source_db:npass_chem_all
  • 11. Outgoing r'ship FOUND_IN to/from Fraxinus Chinensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 12. Outgoing r'ship FOUND_IN to/from Fraxinus Excelsior (Plant) Rel Props:Reference:https://doi.org/10.2174/0929867033456729
  • 13. Outgoing r'ship FOUND_IN to/from Fraxinus Floribunda (Plant) Rel Props:Reference:ISBN:9770972795006; ISBN:9788185042138
  • 14. Outgoing r'ship FOUND_IN to/from Fraxinus Hookeri (Plant) Rel Props:Reference:ISBN:9780387706375
  • 15. Outgoing r'ship FOUND_IN to/from Fraxinus Ornus (Plant) Rel Props:Reference:https://doi.org/10.15482/usda.adc/1239279
  • 16. Outgoing r'ship FOUND_IN to/from Fraxinus Stylosa (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 17. Outgoing r'ship FOUND_IN to/from Fraxinus Szaboana (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 18. Outgoing r'ship FOUND_IN to/from Glycosmis Pseudoracemosa (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 19. Outgoing r'ship FOUND_IN to/from Hemerocallis Citrina (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 20. Outgoing r'ship FOUND_IN to/from Inula Grantioides (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 21. Outgoing r'ship FOUND_IN to/from Isodon Pharicus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 22. Outgoing r'ship FOUND_IN to/from Juniperus Horizontalis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 23. Outgoing r'ship FOUND_IN to/from Lathyrus Tingitanus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 24. Outgoing r'ship FOUND_IN to/from Peucedanum Oroselinum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 25. Outgoing r'ship FOUND_IN to/from Plectranthus Caninus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 26. Outgoing r'ship FOUND_IN to/from Rauvolfia Salicifolia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 27. Outgoing r'ship FOUND_IN to/from Sarcandra Glabra (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 28. Outgoing r'ship FOUND_IN to/from Strychnos Spinosa (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 29. Outgoing r'ship FOUND_IN to/from Tetradium Glabrifolium (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all