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Methyl 3-hydroxy-3-methylbutanoate

PubChem CID: 521979

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Compound Synonyms Methyl 3-hydroxy-3-methylbutanoate, 6149-45-7, 3-Hydroxy-3-methylbutanoic acid methyl ester, methyl 3-hydroxy-3-methylbutyrate, Butyric acid, 3-hydroxy-3-methyl-, methyl ester, Butanoic acid, 3-hydroxy-3-methyl-, methyl ester, DTXSID10334808, Methyl 3-methyl 3-hydroxybutanoate, (CH3)2C(OH)CH2C(O)OCH3, .beta.-Hydroxyisovaleric acid, methyl ester, methyl beta-hydroxyisovalerate, SCHEMBL585604, DTXCID20285897, GAA14945, MFCD29054934, AKOS033848808, beta-Hydroxyisovaleric acid, methyl ester, AS-66159, DB-130111, CS-0187490, 3-hydroxy-3-methyl-butyric acid methyl ester, C75882, EN300-250398, Z2242043764, 837-668-5
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 46.5
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Np Classifier Class Wax monoesters
Deep Smiles COC=O)CCO)C)C
Heavy Atom Count 9.0
Classyfire Class Fatty acyls
Description Methyl 3-hydroxyisovalerate is a member of the class of compounds known as fatty acid methyl esters. Fatty acid methyl esters are compounds containing a fatty acid that is esterified with a methyl group. They have the general structure RC(=O)OR', where R=fatty aliphatic tail or organyl group and R'=methyl group. Methyl 3-hydroxyisovalerate is soluble (in water) and an extremely weak acidic compound (based on its pKa). Methyl 3-hydroxyisovalerate can be found in bilberry and black walnut, which makes methyl 3-hydroxyisovalerate a potential biomarker for the consumption of these food products.
Classyfire Subclass Fatty acid esters
Isotope Atom Count 0.0
Molecular Complexity 107.0
Database Name cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;imppat_phytochem;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name methyl 3-hydroxy-3-methylbutanoate
Prediction Hob 1.0
Class Fatty Acyls
Veber Rule True
Classyfire Superclass Lipids and lipid-like molecules
Xlogp 0.0
Superclass Lipids and lipid-like molecules
Subclass Fatty acid esters
Gsk 4 400 Rule True
Molecular Formula C6H12O3
Prediction Swissadme 0.0
Inchi Key JNURPEZKOSMRMZ-UHFFFAOYSA-N
Silicos It Class Soluble
Fcsp3 0.8333333333333334
Rotatable Bond Count 3.0
Synonyms &beta, -Hydroxyisovaleric acid, methyl ester, Butyric acid, 3-hydroxy-3-methyl-, methyl ester, Methyl 3-hydroxy-3-methylbutanoate, Methyl 3-hydroxyisovalerate, Methyl 3-methyl 3-hydroxybutanoate, Methyl 3-hydroxy-3-methylbutanoic acid, Methyl 3-hydroxyisovaleric acid, methyl 3-hydroxy-3-methylbutanoate, methyl 3-hydroxy-3methylbutanoate
Esol Class Very soluble
Functional Groups CO, COC(C)=O
Compound Name Methyl 3-hydroxy-3-methylbutanoate
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 132.079
Formal Charge 0.0
Monoisotopic Mass 132.079
Hydrogen Bond Acceptor Count 3.0
Molecular Weight 132.16
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aliphatic acyclic compounds
Lipinski Rule Of 5 True
Esol -0.44878580000000007
Inchi InChI=1S/C6H12O3/c1-6(2,8)4-5(7)9-3/h8H,4H2,1-3H3
Smiles CC(C)(CC(=O)OC)O
Np Classifier Biosynthetic Pathway Fatty acids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Taxonomy Direct Parent Fatty acid methyl esters
Np Classifier Superclass Fatty esters

  • 1. Outgoing r'ship FOUND_IN to/from Annona Muricata (Plant) Rel Props:Reference:https://doi.org/10.1002/ffj.2730080103
  • 2. Outgoing r'ship FOUND_IN to/from Artocarpus Heterophyllus (Plant) Rel Props:Reference:https://doi.org/10.1002/ffj.2730070604
  • 3. Outgoing r'ship FOUND_IN to/from Dimocarpus Longan (Plant) Rel Props:Reference:https://doi.org/10.1002/(sici)1099-1026(199607)11:4<223::aid-ffj579>3.0.co;2-b
  • 4. Outgoing r'ship FOUND_IN to/from Juglans Nigra (Plant) Rel Props:Source_db:cmaup_ingredients;fooddb_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Vaccinium Myrtillus (Plant) Rel Props:Source_db:fooddb_chem_all