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Salicyl Alcohol

PubChem CID: 5146

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Compound Synonyms salicyl alcohol, 2-HYDROXYBENZYL ALCOHOL, 90-01-7, 2-(Hydroxymethyl)phenol, Saligenin, Benzenemethanol, 2-hydroxy-, o-Hydroxybenzyl alcohol, Saligenol, 2-Methylolphenol, 2-Hydroxymethylphenol, Diathesin, o-Methylolphenol, o-(Hydroxymethyl)phenol, 2-Hydroxybenzenemethanol, Salicylalkohol, Salicain, salicylic alcohol, alpha-Hydroxy-o-cresol, Benzyl alcohol, o-hydroxy-, alpha,2-Dihydroxytoluene, 2-Hydroxybenzylalcohol, 2-Hydroxybenzylalkohol, Salicyl alcohol [USAN], NSC 3814, MFCD00004617, NSC-3814, EINECS 201-960-5, BRN 1907195, FA1N0842KB, DTXSID9045843, CHEBI:16464, AI3-03990, Salicyl alcohol (USAN), .alpha.-Hydroxy-o-cresol, .alpha.,2-Dihydroxytoluene, SALICYL ALCOHOL [MI], DTXCID7025843, SALICYL ALCOHOL [MART.], SALICYL ALCOHOL [WHO-DD], TOLUENE,ALPHA,2-DIHYDROXY, 4-06-00-05896 (Beilstein Handbook Reference), NCGC00094779-01, SALICYL ALCOHOL (MART.), 2-methylol phenol, CAS-90-01-7, 2-monomethylolphenol, salicylalcohol, salicylsaure, UNII-FA1N0842KB, oMethylolphenol, Saligenine, salicyl-alcohol, 2Methylolphenol, alphaHydroxyocresol, 2Hydroxymethylphenol, 2Hydroxybenzylalkohol, oHydroxybenzyl alcohol, 2hydroxybenzyl alcohol, 2Hydroxybenzenemethanol, o(Hydroxymethyl)phenol, 2-hydoxybenzyl alcohol, 2-hydroxymethyl-phenol, 2-Hydroxymethyl phenol, alpha,2Dihydroxytoluene, Spectrum_000944, Benzyl alcohol, ohydroxy, 2-hydroxy benzyl alcohol, Benzenemethanol, 2hydroxy, Spectrum2_001311, Spectrum3_000896, Spectrum4_000991, Spectrum5_001190, 2-(hydroxymethyl)-phenol, phenol, 2-hydroxymethyl-, bmse000768, SCHEMBL15639, BSPBio_002510, KBioGR_001421, KBioSS_001424, DivK1c_000657, SPECTRUM1500531, SPBio_001401, 2-Hydroxybenzyl alcohol, 99%, CHEMBL280802, HMS502A19, KBio1_000657, KBio2_001424, KBio2_003992, KBio2_006560, KBio3_001812, NSC3814, NINDS_000657, HMS1920P12, HMS2092G13, Pharmakon1600-01500531, HY-B1419, Tox21_111330, CCG-39249, NSC757317, s5562, STL183340, AKOS000249109, Tox21_111330_1, 2-Hydroxybenzyl alcohol Salicyl alcohol, BS-3756, CS-4863, FS67470, NSC-757317, O-Hydroxybenzyl alcohol, Salicyl alcohol, IDI1_000657, NCGC00094779-02, NCGC00094779-03, NCGC00094779-05, SY012296, SBI-0051508.P003, DB-057178, H0223, NS00014668, EN300-39020, C02323, D05790, O10523, AB00052088_02, Q411687, SR-05000002088, 2-Hydroxybenzyl alcohol, purum, >=98.0% (HPLC), SR-05000002088-1, BRD-K08493205-001-02-3, BRD-K08493205-001-04-9, F0001-2205, Z335244902, 201-960-5, 27134-47-0
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 40.5
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCCCC1
Deep Smiles OCcccccc6O
Heavy Atom Count 9.0
Classyfire Class Benzene and substituted derivatives
Description Salicyl alcohol, also known as saligenin or 2-hydroxybenzyl alcohol, is a member of the class of compounds known as benzyl alcohols. Benzyl alcohols are organic compounds containing the phenylmethanol substructure. Salicyl alcohol is soluble (in water) and a very weakly acidic compound (based on its pKa). Salicyl alcohol can be synthesized from phenol and benzyl alcohol. Salicyl alcohol can also be synthesized into salicin. Salicyl alcohol can be found in a number of food items such as red huckleberry, rye, jerusalem artichoke, and ceylon cinnamon, which makes salicyl alcohol a potential biomarker for the consumption of these food products. Salicyl alcohol (saligenin) is precursor of salicylic acid and is formed from salicin by enzymatic hydrolysis by Salicyl-alcohol beta-D-glucosyltransferase or by acid hydrolysis .
Scaffold Graph Node Level C1CCCCC1
Classyfire Subclass Benzyl alcohols
Isotope Atom Count 0.0
Molecular Complexity 83.0
Database Name cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id Q9Y6L6, Q9NPD5, n.a., P0DTD1, Q2KJ64
Iupac Name 2-(hydroxymethyl)phenol
Prediction Hob 1.0
Class Benzene and substituted derivatives
Veber Rule True
Classyfire Superclass Benzenoids
Xlogp 0.7
Superclass Benzenoids
Subclass Benzyl alcohols
Gsk 4 400 Rule True
Molecular Formula C7H8O2
Scaffold Graph Node Bond Level c1ccccc1
Prediction Swissadme 0.0
Inchi Key CQRYARSYNCAZFO-UHFFFAOYSA-N
Silicos It Class Soluble
Fcsp3 0.1428571428571428
Logs -0.076
Rotatable Bond Count 1.0
State Solid
Logd 0.903
Synonyms 2-(Hydroxymethyl)phenol, Saligenin, 2-Monomethylolphenol, O-Hydroxybenzyl alcohol, Salicyl alcohol, monosodium salt, Salicyl alcohol, disodium salt, 2-Methylol phenol, Salicyl alcohol, (ar)-isomer, 2-Hydroxybenzyl alcohol, Salicyl alcohol, salicyl alcohol, saligenin
Esol Class Very soluble
Functional Groups CO, cO
Compound Name Salicyl Alcohol
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 124.052
Formal Charge 0.0
Monoisotopic Mass 124.052
Hydrogen Bond Acceptor Count 2.0
Molecular Weight 124.14
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aromatic homomonocyclic compounds
Lipinski Rule Of 5 True
Esol -1.4968951333333331
Inchi InChI=1S/C7H8O2/c8-5-6-3-1-2-4-7(6)9/h1-4,8-9H,5H2
Smiles C1=CC=C(C(=C1)CO)O
Nring 1.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Taxonomy Direct Parent Benzyl alcohols

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  • 2. Outgoing r'ship FOUND_IN to/from Datisca Cannabina (Plant) Rel Props:Reference:
  • 3. Outgoing r'ship FOUND_IN to/from Gardenia Jasminoides (Plant) Rel Props:Reference:ISBN:9788172362300
  • 4. Outgoing r'ship FOUND_IN to/from Paeonia Delavayi (Plant) Rel Props:Reference:
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  • 6. Outgoing r'ship FOUND_IN to/from Paeonia Lactiflora (Plant) Rel Props:Reference:
  • 7. Outgoing r'ship FOUND_IN to/from Paeonia Obovata (Plant) Rel Props:Reference:
  • 8. Outgoing r'ship FOUND_IN to/from Paeonia Officinalis (Plant) Rel Props:Reference:
  • 9. Outgoing r'ship FOUND_IN to/from Paeonia Rockii (Plant) Rel Props:Reference:
  • 10. Outgoing r'ship FOUND_IN to/from Paeonia Suffruticosa (Plant) Rel Props:Reference:
  • 11. Outgoing r'ship FOUND_IN to/from Paeonia Veitchii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 12. Outgoing r'ship FOUND_IN to/from Populus Deltoides (Plant) Rel Props:Reference:ISBN:9788172362461
  • 13. Outgoing r'ship FOUND_IN to/from Salix Caprea (Plant) Rel Props:Reference:ISBN:9788172363093; ISBN:9788185042145
  • 14. Outgoing r'ship FOUND_IN to/from Tragia Cannabina (Plant) Rel Props:Reference:
  • 15. Outgoing r'ship FOUND_IN to/from Trema Cannabina (Plant) Rel Props:Reference:
  • 16. Outgoing r'ship FOUND_IN to/from Urtica Ardens (Plant) Rel Props:Reference:
  • 17. Outgoing r'ship FOUND_IN to/from Urtica Cannabina (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 18. Outgoing r'ship FOUND_IN to/from Urtica Dioica (Plant) Rel Props:Reference:
  • 19. Outgoing r'ship FOUND_IN to/from Urtica Hyperborea (Plant) Rel Props:Reference:
  • 20. Outgoing r'ship FOUND_IN to/from Urtica Magellanica (Plant) Rel Props:Reference:
  • 21. Outgoing r'ship FOUND_IN to/from Urtica Parviflora (Plant) Rel Props:Reference:
  • 22. Outgoing r'ship FOUND_IN to/from Urtica Pilulifera (Plant) Rel Props:Reference:
  • 23. Outgoing r'ship FOUND_IN to/from Urtica Triangularis (Plant) Rel Props:Reference:
  • 24. Outgoing r'ship FOUND_IN to/from Urtica Urens (Plant) Rel Props:Reference: