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12-O-Decanoylphorbol-13-(2-methylbutyrate)

PubChem CID: 476547

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Compound Synonyms 12-O-Decanoylphorbol-13-(2-methylbutyrate), 250268-56-5, Decanoic acid, (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-9a-(2-methyl-1-oxobutoxy)-5-oxo-1H-cyclopropa(3,4)benz(1,2-e)azulen-9-yl ester, Decanoic acid, (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-9a-(2-methyl-1-oxobutoxy)-5-oxo-1H-cyclopropa[3,4]benz[1,2-e]azulen-9-yl ester, DTXSID20947887, [dihydroxy-(hydroxymethyl)-tetramethyl-(2-methylbutanoyloxy)-oxo-[?]yl] decanoate, 4a,7b-Dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-9a-[(2-methylbutanoyl)oxy]-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yl decanoate
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 130.0
Hydrogen Bond Donor Count 3.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CCC2C1CCCC1C3CC3CCC21
Np Classifier Class Tetracyclic diterpenoids, Tigliane diterpenoids
Deep Smiles CCCCCCCCCC=O)O[C@@H][C@@H]C)[C@@]O)CC[C@]6OC=O)CCC))C))))C3C)C))))C=CC[C@]C7C=CC5=O))C))))O)))CO
Heavy Atom Count 43.0
Classyfire Class Prenol lipids
Scaffold Graph Node Level OC1CCC2C1CCCC1C3CC3CCC21
Classyfire Subclass Diterpenoids
Isotope Atom Count 0.0
Molecular Complexity 1150.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 5.0
Iupac Name [(1S,6R,13S,14R,15R)-1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-13-(2-methylbutanoyloxy)-5-oxo-14-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dienyl] decanoate
Prediction Hob 0.0
Veber Rule False
Classyfire Superclass Lipids and lipid-like molecules
Xlogp 5.8
Gsk 4 400 Rule False
Molecular Formula C35H54O8
Scaffold Graph Node Bond Level O=C1C=CC2C1CC=CC1C3CC3CCC21
Prediction Swissadme 0.0
Inchi Key MJYTZOPOHSKFOT-ZAJMFEHASA-N
Silicos It Class Poorly soluble
Fcsp3 0.8
Logs -4.933
Rotatable Bond Count 15.0
Logd 4.161
Synonyms 12-o-decanoylphorbol-13-(2-methylbutyrate)
Esol Class Poorly soluble
Functional Groups CC(=O)OC, CC1=CCCC1=O, CC=C(C)C, CO
Compound Name 12-O-Decanoylphorbol-13-(2-methylbutyrate)
Prediction Hob Swissadme 0.0
Exact Mass 602.382
Formal Charge 0.0
Monoisotopic Mass 602.382
Hydrogen Bond Acceptor Count 8.0
Molecular Weight 602.8
Gi Absorption False
Covalent Unit Count 1.0
Total Atom Stereocenter Count 9.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 False
Esol -6.228815800000001
Inchi InChI=1S/C35H54O8/c1-8-10-11-12-13-14-15-16-27(37)42-30-23(5)34(41)25(28-32(6,7)35(28,30)43-31(39)21(3)9-2)18-24(20-36)19-33(40)26(34)17-22(4)29(33)38/h17-18,21,23,25-26,28,30,36,40-41H,8-16,19-20H2,1-7H3/t21?,23-,25?,26?,28?,30-,33-,34-,35-/m1/s1
Smiles CCCCCCCCCC(=O)O[C@@H]1[C@H]([C@]2(C(C=C(C[C@]3(C2C=C(C3=O)C)O)CO)C4[C@@]1(C4(C)C)OC(=O)C(C)CC)O)C
Nring 4.0
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Diterpenoids

  • 1. Outgoing r'ship FOUND_IN to/from Croton Tiglium (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all