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Epiafzelechin 3-O-gallate

PubChem CID: 467295

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Compound Synonyms Epiafzelechin 3-O-gallate, 108907-43-3, (-)-epiafzelechin 3-O-gallate, [(2R,3R)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate, (-)-Epiafzelechin-3-O-gallate, (-)-Epiafzelechin 3-gallate, Benzoic acid, 3,4,5-trihydroxy-, (2R,3R)-3,4-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-2H-1-benzopyran-3-yl ester, (2R,3R)-5,7-Dihydroxy-2-(4-hydroxyphenyl)chroman-3-yl 3,4,5-trihydroxybenzoate, (2R,3R)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3-yl 3,4,5-trihydroxybenzoate, (-)-Epiafzelechin Gallate, epiafzelechin 3-gallate, 3-Galloyl-(-)-epiafzelechin, CHEMBL159706, SCHEMBL9100860, SDC4N7B392, CHEBI:136552, DTXSID701308092, GLXC-16048, Epiafzelechin 3-O-gallate, (-)-, HY-N8589, LMPK12020038, AKOS040761680, FS-8203, DA-68942, CS-0148674, 5,7-Dihydroxy-2-(4-hydroxyphenyl)chroman-3-yl 3,4,5-trihydroxybenzoate, [(2R,3R)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-3-yl] 3,4,5-trihydroxybenzoate, Benzoic acid, 3,4,5-trihydroxy-, 3,4-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-2H-1-benzopyran-3-yl ester, (2R-cis)-
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 157.0
Hydrogen Bond Donor Count 6.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC(CC1CC2CCCCC2CC1C1CCCCC1)C1CCCCC1
Np Classifier Class Flavan-3-ols
Deep Smiles Occcccc6))[C@H]OcccO)ccc6C[C@H]%10OC=O)cccO)ccc6)O))O))))))))))O
Heavy Atom Count 31.0
Classyfire Class Flavonoids
Description Isolated from Camellia sinensis variety assamica (oolong tea). (-)-Epiafzelechin 3-gallate is found in tea.
Scaffold Graph Node Level OC(OC1CC2CCCCC2OC1C1CCCCC1)C1CCCCC1
Classyfire Subclass Flavans
Isotope Atom Count 0.0
Molecular Complexity 610.0
Database Name cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 2.0
Iupac Name [(2R,3R)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
Prediction Hob 0.0
Class Flavonoids
Veber Rule False
Classyfire Superclass Phenylpropanoids and polyketides
Xlogp 1.9
Superclass Phenylpropanoids and polyketides
Subclass Flavans
Gsk 4 400 Rule False
Molecular Formula C22H18O9
Scaffold Graph Node Bond Level O=C(OC1Cc2ccccc2OC1c1ccccc1)c1ccccc1
Prediction Swissadme 0.0
Inchi Key SDZPYNMXGUHFMZ-TZIWHRDSSA-N
Silicos It Class Soluble
Fcsp3 0.1363636363636363
Logs -4.005
Rotatable Bond Count 4.0
Logd 1.776
Synonyms (-)-Epiafzelechin 3-gallate, (-)-Epiafzelechin gallic acid, 3-Galloyl-(-)-epiafzelechin, Epiafzelechin 3-O-gallate, (-)-Epiafzelechin 3-O-gallate, (-)-Epiafzelechin 3-O-gallic acid, Epiafzelechin 3-O-gallic acid, (-)-Epiafzelechin 3-gallic acid, (-)-Epiafzelechin gallate, (-)-epiafzelechin-3-o-gallate, 3-galloyl-(-)-epiafzelechin
Esol Class Soluble
Functional Groups cC(=O)OC, cO, cOC
Compound Name Epiafzelechin 3-O-gallate
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 426.095
Formal Charge 0.0
Monoisotopic Mass 426.095
Hydrogen Bond Acceptor Count 9.0
Molecular Weight 426.4
Gi Absorption False
Covalent Unit Count 1.0
Total Atom Stereocenter Count 2.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aromatic heteropolycyclic compounds
Lipinski Rule Of 5 True
Esol -3.83361481935484
Inchi InChI=1S/C22H18O9/c23-12-3-1-10(2-4-12)21-19(9-14-15(25)7-13(24)8-18(14)30-21)31-22(29)11-5-16(26)20(28)17(27)6-11/h1-8,19,21,23-28H,9H2/t19-,21-/m1/s1
Smiles C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC=C(C=C3)O)OC(=O)C4=CC(=C(C(=C4)O)O)O
Nring 4.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule False
Taxonomy Direct Parent Flavan-3-ols
Np Classifier Superclass Flavonoids

  • 1. Outgoing r'ship FOUND_IN to/from Camellia Sinensis (Plant) Rel Props:Source_db:cmaup_ingredients;fooddb_chem_all;npass_chem_all