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Bouvardin, 5-(N-methyl-L-tyrosine)-

PubChem CID: 462402

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Compound Synonyms Bouvardin, 5-(N-methyl-L-tyrosine)-, 64725-24-2, hydroxy-[(4-methoxyphenyl)methyl]-hexamethyl-[?]hexone, (1R,4S,7S,10S,13R,16R)-24-Hydroxy-10-[(4-methoxyphenyl)methyl]-4,7,9,13,15,29-hexamethyl-22-oxa-3,6,9,12,15,29-hexazatetracyclo[14.12.2.218,21.123,27]tritriaconta-18,20,23,25,27(31),32-hexaene-2,5,8,11,14,30-hexone
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 187.0
Hydrogen Bond Donor Count 4.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CCC(C)CC(CC2CCCCC2)C(C)CCC(C)CC2CC3CCC(CC3)CC3CCCC(C3)CC(CC2C)C(C)CC1
Np Classifier Class Cyclic peptides
Deep Smiles COcccccc6))C[C@H]C=O)N[C@H]C)C=O)NC)[C@@H]Ccccccc6))OcccC[C@@H]NC%14=O))C))C=O)N[C@H]C=O)N[C@H]C=O)N%26C)))C))))C))))))ccc6O
Heavy Atom Count 55.0
Classyfire Class Carboxylic acids and derivatives
Scaffold Graph Node Level OC1CNC(O)C2CC3CCCC(C3)OC3CCC(CC3)CC(NC(O)CNC(O)C(CC3CCCCC3)NC(O)CN1)C(O)N2
Classyfire Subclass Amino acids, peptides, and analogues
Isotope Atom Count 0.0
Molecular Complexity 1400.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 6.0
Iupac Name (1R,4S,7S,10S,13R,16R)-24-hydroxy-10-[(4-methoxyphenyl)methyl]-4,7,9,13,15,29-hexamethyl-22-oxa-3,6,9,12,15,29-hexazatetracyclo[14.12.2.218,21.123,27]tritriaconta-18,20,23,25,27(31),32-hexaene-2,5,8,11,14,30-hexone
Veber Rule False
Classyfire Superclass Organic acids and derivatives
Xlogp 3.0
Gsk 4 400 Rule False
Molecular Formula C40H48N6O9
Scaffold Graph Node Bond Level O=C1CNC(=O)C2Cc3cccc(c3)Oc3ccc(cc3)CC(NC(=O)CNC(=O)C(Cc3ccccc3)NC(=O)CN1)C(=O)N2
Inchi Key VXVGFMUNENQGFW-CRSALWQCSA-N
Silicos It Class Poorly soluble
Rotatable Bond Count 3.0
Synonyms deoxybouvardin
Esol Class Poorly soluble
Functional Groups CC(=O)NC, CN(C)C(C)=O, CNC(C)=O, cO, cOC, cOc
Compound Name Bouvardin, 5-(N-methyl-L-tyrosine)-
Exact Mass 756.348
Formal Charge 0.0
Monoisotopic Mass 756.348
Hydrogen Bond Acceptor Count 9.0
Molecular Weight 756.8
Gi Absorption False
Covalent Unit Count 1.0
Total Atom Stereocenter Count 6.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C40H48N6O9/c1-22-35(48)42-23(2)38(51)44(4)30(18-25-8-13-28(54-7)14-9-25)37(50)43-24(3)39(52)46(6)32-19-26-10-15-29(16-11-26)55-34-21-27(12-17-33(34)47)20-31(36(49)41-22)45(5)40(32)53/h8-17,21-24,30-32,47H,18-20H2,1-7H3,(H,41,49)(H,42,48)(H,43,50)/t22-,23-,24+,30-,31+,32+/m0/s1
Smiles C[C@H]1C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@@H](C(=O)N([C@@H]2CC3=CC=C(C=C3)OC4=C(C=CC(=C4)C[C@H](C(=O)N1)N(C2=O)C)O)C)C)CC5=CC=C(C=C5)OC)C)C
Np Classifier Biosynthetic Pathway Amino acids and Peptides
Defined Bond Stereocenter Count 0.0
Egan Rule False
Np Classifier Superclass Oligopeptides

  • 1. Outgoing r'ship FOUND_IN to/from Rubia Cordifolia (Plant) Rel Props:Reference:https://www.ncbi.nlm.nih.gov/pubmed/18078747