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Inophyllum A

PubChem CID: 455248

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Compound Synonyms Inophyllum A, 41135-07-3, NSC 733298, CHEMBL132692, DTXSID20194071, NSC733298, 2H,6H,10H-Benzo(1,2-b:3,4-b':5,6-b'')tripyran-2-one, 11,12-dihydro-12-hydroxy-6,6,10,11-tetramethyl-4-phenyl-, (10R-(10alpha,11alpha,12alpha))-, hydroxy-tetramethyl-phenyl-[?]one, (16R,17R,18S)-18-hydroxy-10,10,16,17-tetramethyl-6-phenyl-3,9,15-trioxatetracyclo(12.4.0.02,7.08,13)octadeca-1(14),2(7),5,8(13),11-pentaen-4-one, (16R,17R,18S)-18-hydroxy-10,10,16,17-tetramethyl-6-phenyl-3,9,15-trioxatetracyclo[12.4.0.02,7.08,13]octadeca-1(14),2(7),5,8(13),11-pentaen-4-one, SCHEMBL6731413, DTXCID30116562, 12-Hydroxy-6,6,10,11-tetramethyl-4-phenyl-11,12-dihydro-6H,10H-dipyrano[2,3-f, 2'',3''-h]chromen-2-one, BDBM50029981, NSC-733298, (2R,3S,4S)-4-Hydroxy-2,3,10,10-tetramethyl-8-phenyl-2H-pyrano[6,5-f]2H-pyrano[6,5-h]chroman-6-one
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 65.0
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CC(C2CCCCC2)C2C3CCCCC3C3CCCCC3C2C1
Np Classifier Class Pyranocoumarins, Simple coumarins
Deep Smiles C[C@H]OccC=CCOc6ccc%10[C@H][C@H]%14C))O)))oc=O)cc6cccccc6))))))))))))))C)C
Heavy Atom Count 30.0
Classyfire Class Neoflavonoids
Scaffold Graph Node Level OC1CC(C2CCCCC2)C2C3OCCCC3C3OCCCC3C2O1
Classyfire Subclass Prenylated neoflavonoids
Isotope Atom Count 0.0
Molecular Complexity 749.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 3.0
Uniprot Id Q72547
Iupac Name (16R,17R,18S)-18-hydroxy-10,10,16,17-tetramethyl-6-phenyl-3,9,15-trioxatetracyclo[12.4.0.02,7.08,13]octadeca-1(14),2(7),5,8(13),11-pentaen-4-one
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Phenylpropanoids and polyketides
Xlogp 4.1
Gsk 4 400 Rule False
Molecular Formula C25H24O5
Scaffold Graph Node Bond Level O=c1cc(-c2ccccc2)c2c3c(c4c(c2o1)CCCO4)C=CCO3
Prediction Swissadme 1.0
Inchi Key BXENDTPSKAICGV-QTCYRWPVSA-N
Silicos It Class Poorly soluble
Fcsp3 0.32
Logs -3.892
Rotatable Bond Count 1.0
Logd 4.637
Synonyms inophyllum a
Esol Class Moderately soluble
Functional Groups CO, c=O, cC=CC, cOC, coc
Compound Name Inophyllum A
Prediction Hob Swissadme 1.0
Exact Mass 404.162
Formal Charge 0.0
Monoisotopic Mass 404.162
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 404.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 3.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -4.837231066666668
Inchi InChI=1S/C25H24O5/c1-13-14(2)28-22-16-10-11-25(3,4)30-23(16)19-17(15-8-6-5-7-9-15)12-18(26)29-24(19)20(22)21(13)27/h5-14,21,27H,1-4H3/t13-,14+,21-/m0/s1
Smiles C[C@H]1[C@H](OC2=C([C@H]1O)C3=C(C(=CC(=O)O3)C4=CC=CC=C4)C5=C2C=CC(O5)(C)C)C
Nring 5.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Coumarins

  • 1. Outgoing r'ship FOUND_IN to/from Calophyllum Inophyllum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all