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Trimethylcolchicinic Acid

PubChem CID: 453131

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Compound Synonyms TRIMETHYLCOLCHICINIC ACID, N-Deacetylcolchiceine, 3482-37-9, N-Deacetyl Colchiceine, Desacetylcolchiceine, Deacetylcholchiceine, Desacetylcholchiceine, SKF 284, Colchiceine, N-deacetyl-, Colchicinic acid, trimethyl-, NSC 36796, UNII-333BVY614O, 333BVY614O, EINECS 222-464-5, BRN 3008992, (7S)-7-amino-10-hydroxy-1,2,3-trimethoxy-6,7-dihydro-5H-benzo[a]heptalen-9-one, MLS002153887, 4-14-00-00937 (Beilstein Handbook Reference), NSC36796, NSC-36796, SMR000112547, COLCHICINIC ACID, O,O',O''-TRIMETHYL-, (S)-7-Amino-6,7-dihydro-10-hydroxy-1,2,3-trimethoxybenzo(a)heptalen-9(5H)-one, Benzo(a)heptalen-9(5H)-one, 7-amino-6,7-dihydro-10-hydroxy-1,2,3-trimethoxy-, (S)-, (S)-7-amino-6,7-dihydro-10-hydroxy-1,2,3-trimethoxybenzo[a]heptalen-9(5H)-one, BENZO(A)HEPTALEN-9(5H)-ONE, 7-AMINO-6,7-DIHYDRO-10-HYDROXY-1,2,3-TRIMETHOXY-, (7S)-, DTXSID90875143, Prestwick3_000580, Desacetylcolchiceine, N-Deacetylcolchiceine, NSC 36796, BSPBio_000400, BPBio1_000440, CHEMBL517186, cid_453131, Desacetyl Colchicine D-tartrate, Colchiceine, N-deacetyl-(VAN), Colchiceine, N-deacetyl-(8CI), BDBM79208, Colchiceine, N-deacetyl- (VAN), IRVWPZRYDQROLU-ZDUSSCGKSA-N, DTXCID701013265, DTXSID701031742, HMS2096D22, HMS2268E20, STL564563, AKOS015969698, AKOS037623125, (7S)-7-Amino-6,7-dihydro-10-hydroxy-1,2,3-trimethoxy-benzo[a]heptalen-9(5H)-one, Colchiceine, N-deacetyl-(VAN) (8CI), NCGC00179572-01, AB00513865, NS00050163, BRD-K84300594-001-02-6, Q27256218, (7S)-7-amino-9-hydroxy-1,2,3-trimethoxy-6,7-dihydrobenzo[a]heptalen-10(5H)-one, (7S)-7-azanyl-1,2,3-trimethoxy-10-oxidanyl-6,7-dihydro-5H-benzo[a]heptalen-9-one, Benzo[a]heptalen-9(5H)-one, 7-amino-6,7-dihydro-10-hydroxy -1,2,3-trimethoxy-, (7S)-, Benzo(a)heptalen-9(5H)-one, 7-amino-6,7-dihydro-10-hydroxy-1,2,3-trimethoxy-, (S)-(9CI)
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 91.0
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CCCC2C(CCCC3CCCCC32)C1
Np Classifier Class Phenethylisoquinoline alkaloids
Deep Smiles COccOC))cOC))ccc6-ccccc=O)cc7[C@H]CC%12))N)))))O
Heavy Atom Count 25.0
Classyfire Class Tropones
Scaffold Graph Node Level OC1CCCC2C(CCCC3CCCCC32)C1
Classyfire Subclass Tropolones
Isotope Atom Count 0.0
Molecular Complexity 623.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 1.0
Iupac Name (7S)-7-amino-10-hydroxy-1,2,3-trimethoxy-6,7-dihydro-5H-benzo[a]heptalen-9-one
Veber Rule True
Classyfire Superclass Hydrocarbon derivatives
Xlogp 0.9
Gsk 4 400 Rule True
Molecular Formula C19H21NO5
Scaffold Graph Node Bond Level O=c1cccc2c(c1)CCCc1ccccc1-2
Inchi Key IRVWPZRYDQROLU-ZDUSSCGKSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 3.0
Synonyms trimethylcolchicinic acid
Esol Class Soluble
Functional Groups CN, c=O, cO, cOC
Compound Name Trimethylcolchicinic Acid
Exact Mass 343.142
Formal Charge 0.0
Monoisotopic Mass 343.142
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 343.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C19H21NO5/c1-23-16-8-10-4-6-13(20)12-9-15(22)14(21)7-5-11(12)17(10)19(25-3)18(16)24-2/h5,7-9,13H,4,6,20H2,1-3H3,(H,21,22)/t13-/m0/s1
Smiles COC1=C(C(=C2C(=C1)CC[C@@H](C3=CC(=O)C(=CC=C32)O)N)OC)OC
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Colchicum Luteum (Plant) Rel Props:Reference:ISBN:9780387706375