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Trachelogenin

PubChem CID: 452855

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Compound Synonyms Trachelogenin, 34209-69-3, (-)-Trachelogenin, UNII-379VHZ3K1I, 2(3H)-Furanone, dihydro-3-hydroxy-3-vanillyl-4-veratryl-, 379VHZ3K1I, 2(3H)-Furanone, 4-[(3,4-dimethoxyphenyl)methyl]dihydro-3-hydroxy-3-[(4-hydroxy-3-methoxyphenyl)methyl]-, (3S,4S)-, TRACHELOGENIN, (-)-, CHEBI:9647, (3S,4S)-4-[(3,4-dimethoxyphenyl)methyl]-3-hydroxy-3-[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one, DTXSID50187799, 2(3H)-Furanone, 4-((3,4-dimethoxyphenyl)methyl)dihydro-3-hydroxy-3-((4-hydroxy-3-methoxyphenyl)methyl)-, (3S,4S)-, (3S,4S)-4-[(3,4-dimethoxyphenyl)methyl]-3-hydroxy-3-[(4-hydroxy-3-methoxy-phenyl)methyl]tetrahydrofuran-2-one, 2(3H)-FURANONE, 4-((3,4-DIMETHOXYPHENYL)METHYL)DIHYDRO-3-HYDROXY-3-((4-HYDROXY-3-METHOXYPHENYL)METHYL)-, (3S-CIS)-, (3S,4S)-4-((3,4-dimethoxyphenyl)methyl)-3-hydroxy-3-((4-hydroxy-3-methoxy-phenyl)methyl)tetrahydrofuran-2-one, CHEMBL491178, MEGxp0_001798, SCHEMBL3980011, ACon1_002414, DTXCID60110290, HY-N7934, AKOS030573612, NCGC00169870-01, DA-78567, MS-26437, CS-0138835, BRD-K17107446-001-01-9, Q26359226
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 94.5
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CCC(CC2CCCCC2)C1CC1CCCCC1
Np Classifier Class Dibenzylbutyrolactone lignans
Deep Smiles COcccccc6OC)))))C[C@H]COC=O)[C@]5O)Ccccccc6)OC)))O
Heavy Atom Count 28.0
Classyfire Class Furanoid lignans
Scaffold Graph Node Level OC1OCC(CC2CCCCC2)C1CC1CCCCC1
Classyfire Subclass Tetrahydrofuran lignans
Isotope Atom Count 0.0
Molecular Complexity 527.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 2.0
Iupac Name (3S,4S)-4-[(3,4-dimethoxyphenyl)methyl]-3-hydroxy-3-[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Lignans, neolignans and related compounds
Xlogp 2.8
Gsk 4 400 Rule True
Molecular Formula C21H24O7
Scaffold Graph Node Bond Level O=C1OCC(Cc2ccccc2)C1Cc1ccccc1
Prediction Swissadme 1.0
Inchi Key YFVZKLQNMNKWSB-BTYIYWSLSA-N
Silicos It Class Moderately soluble
Fcsp3 0.3809523809523809
Logs -4.09
Rotatable Bond Count 7.0
Logd 2.86
Synonyms trachelogenin
Esol Class Soluble
Functional Groups CO, COC(C)=O, cO, cOC
Compound Name Trachelogenin
Prediction Hob Swissadme 1.0
Exact Mass 388.152
Formal Charge 0.0
Monoisotopic Mass 388.152
Hydrogen Bond Acceptor Count 7.0
Molecular Weight 388.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 2.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -3.879922057142858
Inchi InChI=1S/C21H24O7/c1-25-17-7-5-13(9-19(17)27-3)8-15-12-28-20(23)21(15,24)11-14-4-6-16(22)18(10-14)26-2/h4-7,9-10,15,22,24H,8,11-12H2,1-3H3/t15-,21-/m0/s1
Smiles COC1=C(C=C(C=C1)C[C@H]2COC(=O)[C@@]2(CC3=CC(=C(C=C3)O)OC)O)OC
Nring 3.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Lignans

  • 1. Outgoing r'ship FOUND_IN to/from Arctium Lappa (Plant) Rel Props:Reference:https://www.ncbi.nlm.nih.gov/pubmed/22396124
  • 2. Outgoing r'ship FOUND_IN to/from Ipomoea Cairica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Trachelospermum Asiaticum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Trachelospermum Axillare (Plant) Rel Props:Reference:ISBN:9788172363093; ISBN:9788185042145
  • 5. Outgoing r'ship FOUND_IN to/from Trachelospermum Jasminoides (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all