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Cocaine

PubChem CID: 446220

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Compound Synonyms cocaine, Benzoylmethylecgonine, Neurocaine, Kokain, L-Cocaine, Cocain, Cocaina, beta-Cocain, (-)-Cocaine, cocainum, Methyl Benzoylecgonine, l-Cocain, Eritroxilina, Erytroxylin, Bernies, Kokayeen, Burese, Corine, Kokan, Dama blanca, Pimp's drug, 1-Cocaine, White girl or lady, Star-spangled powder, Leaf, Snow, Nose candy, Cocaine free base, Cocaine, l-, 50-36-2, Coke, C Carrie, Blow [Street Name], Girl [Street Name], Lady [Street Name], Rock [Street Name], Toot [Street Name], Cecil [Street Name], Flake [Street Name], (r)-(-)-cocaine, Bernice [Street Name], CHEBI:27958, HSDB 6469, Ecgonine, methyl ester, benzoate (ester), Gold dust [Street Name], 2-beta-Carbomethoxy-3-beta-benzoxytropane, Happy dust [Street Name], UNII-I5Y540LHVR, I5Y540LHVR, Bernice, Cholly, Cecil, Girl, 2beta-Carbomethoxy-3beta-benzoxytropane, Happy dust, Gold dust, IDS-NC-004, Star dust, 3-Tropanylbenzoate-2-carboxylic acid methyl ester, Cholly [Street Name], Cocaine [USP:BAN], (1R,2R,3S,5S)-2-Methoxycarbonyltropan-3-yl benzoate, 2-beta-Tropanecarboxylic acid, 3-beta-hydroxy-, methyl ester, benzoate (ester), EINECS 200-032-7, RX0041, Star dust [Street Name], Green gold [Street Name], RX-0041, Happy trails [Street Name], Methyl 3beta-hydroxy-1alphaH,5alphaH-tropane-2beta-carboxylate benzoate (ester), Jam, DTXSID2038443, Crack cocaine, 2-Methyl-3beta-hydroxy-1alphaH,5alphaH-tropane-2beta-carboxylate benzoate (ester), 3beta-Hydroxy-1alphaH,5alphaH-tropane-2beta-carboxylic acid methyl ester benzoate, 1-alpha-H,5-alpha-H-Tropane-2-beta-carboxylic acid, 3-beta-hydroxy-, methyl ester, benzoate, 3-(Benzoyloxy)-8-methyl-8-azabicyclo-(3.2.1)octane-2-carboxylic acid methyl ether, methyl (1R,2R,3S,5S)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate, Methyl 3-beta-hydroxy-1-alpha-H,5-alpha-H-tropane-2-beta-carboxylate benzoate (ester), Blow (Street Name), Girl (Street Name), Lady (Street Name), Rock (Street Name), Toot (Street Name), Ecgonine methyl ester benzoate (ester), Cecil (Street Name), COC, Flake (Street Name), (1R,2R,3S,5S)-2-(methoxycarbonyl)tropan-3-yl benzoate, Cholly (Street Name), Cocaine (USP:BAN), Bernice (Street Name), Crack, Flake, Blow, Lady, Toot, Happy trails, COCAINE (MART.), COCAINE [MART.], Green gold, Gold dust (Street Name), Star dust (Street Name), 3beta-Hydroxy-2beta-tropanecarboxylic acid methyl ester benzoate (ester), 8-Azabicyclo(3.2.1)octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, (1R-(exo,exo))-, Green gold (Street Name), Happy dust (Street Name), Happy trails (Street Name), methyl [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate, C' Carrie, COCAINE (USP MONOGRAPH), COCAINE [USP MONOGRAPH], Sleighride, Badrock, Bazooka, Blizzard, Cabello, Charlie, Cocktail, Goofball, Moonrocks, Blast, Candy, Caviar, Freeze, Heaven, Snort, Trails, Coca, Cola, Hell, Toke, Yeyo, beta-Cocaine, Bouncing Powder, Chicken Scratch, Happy powder, Florida Snow, Sweet Stuff, Prime Time, Foo Foo, Kibbles n' Bits, Snow (birds), G-Rock, [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid, methyl ester, METHYL (1R,2R,3S,5S)-3-(BENZOYLOXY)-8-METHYL-8-AZABICYCLO(3.2.1) OCTANE-2-CARBOXYLATE, methyl (1R,2R,3S,5S)-8-methyl-3-[(phenylcarbonyl)oxy]-8-azabicyclo[3.2.1]octane-2-carboxylate, Ecgonine methyl ester benzoate, Line, methyl (1R,2R,3S,5S)-3-(benzoyloxy)-8-methyl-8-azabicyclo(3.2.1)octane-2-carboxylate, methyl (1R-(exo,exo))-3-(benzoyloxy)-8-methyl-8-azabicyclo(3.2.1)octane-2-carboxylate, (1R-(exo,exo))-3-(benzoyloxy)-8-methyl-8-azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester, Cocaine (-), 1i7z, COCAINE [VANDF], COCAINUM [HPUS], COCAINE [HSDB], COCAINE [MI], COCAINE [WHO-DD], Epitope ID:158626, SCHEMBL21930, CHEMBL370805, GTPL2286, DEA No. 9041, BDBM22418, Cocaine, 1mg/ml in Acetonitrile, 1q72, DTXCID501030562, Cocaine 0.1 mg/ml in Acetonitrile, Cocaine 1.0 mg/ml in Acetonitrile, L-Cocaine (1.0 mg/ml in Methanol), AKOS015965554, DB00907, FC111889, NS00000403, C01416, Q41576, [1R-(exo,exo)]-3-(Benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic Acid, 3.BETA.-HYDROXY-2.BETA.-TROPANECARBOXYLIC ACID METHYL ESTER BENZOATE (ESTER), methyl (1R,2R,3S,5S)-3-benzoyloxy-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate, METHYL 3B-HYDROXY-1.ALPHA.H,5.ALPHA.H-TROPANE-2.BETA.-CARBOXYLATE BENZOATE (ESTER), METHYL 3B-HYDROXY-1alphaH,5alphaH-TROPANE-2beta-CARBOXYLATE BENZOATE (ESTER), 1-alpha-H,5-alpha-H-Tropane-2-beta-carboxylic acid, 3-beta-hydroxy-, methyl ester, benzoate (ester) (8CI), 200-032-7, 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, (1R,2R,3S,5S)- (9CI)
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 55.8
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC(CC1CC2CCC(C2)C1)C1CCCCC1
Np Classifier Class Tropane alkaloids
Deep Smiles COC=O)[C@H][C@H]C[C@H]N[C@@H]6CC5)))C))))OC=O)cccccc6
Heavy Atom Count 22.0
Classyfire Class Benzene and substituted derivatives
Scaffold Graph Node Level OC(OC1CC2CCC(C1)N2)C1CCCCC1
Classyfire Subclass Benzoic acids and derivatives
Isotope Atom Count 0.0
Molecular Complexity 432.0
Database Name cmaup_ingredients;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 4.0
Uniprot Id P23141, O00748, P08684, P11712, P10635, P20815, P24462, P10632, P23975, P31645, Q01959, O15244, Q14524, Q9Y5Y9, Q9UI33, P11229, P08172, P23977, Q99720, P31652, Q9WTR4, Q9GJT6, Q9R1M7, Q12809, P27922, Q9NY46, Q16445, P08482, Q63380, n.a., Q61327
Iupac Name methyl (1R,2R,3S,5S)-3-benzoyloxy-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate
Prediction Hob 1.0
Class Benzene and substituted derivatives
Veber Rule True
Classyfire Superclass Benzenoids
Target Id NPT246, NPT296, NPT295, NPT228, NPT98
Xlogp 2.3
Superclass Benzenoids
Subclass Benzoic acids and derivatives
Gsk 4 400 Rule True
Molecular Formula C17H21NO4
Scaffold Graph Node Bond Level O=C(OC1CC2CCC(C1)N2)c1ccccc1
Prediction Swissadme 1.0
Inchi Key ZPUCINDJVBIVPJ-LJISPDSOSA-N
Silicos It Class Soluble
Fcsp3 0.5294117647058824
Logs -2.851
Rotatable Bond Count 5.0
State Solid
Logd 1.518
Synonyms (-)-Cocaine, 2-Methyl-3beta-hydroxy-1alphah,5alphah-tropane-2beta-carboxylate benzoate (ester), [1R-(exo,exo)]-3-(Benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid, methyl ester, Benzoylmethylecgonine, beta-Cocain, Cocain, Cocaina, Cocainum, Kokain, L-Cocain, L-Cocaine, Methyl [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate, Methyl benzoylecgonine, Neurocaine, 2-Methyl-3b-hydroxy-1alphah,5alphah-tropane-2b-carboxylate benzoate (ester), 2-Methyl-3b-hydroxy-1alphah,5alphah-tropane-2b-carboxylic acid benzoic acid (ester), 2-Methyl-3beta-hydroxy-1alphah,5alphah-tropane-2beta-carboxylic acid benzoic acid (ester), 2-Methyl-3β-hydroxy-1alphah,5alphah-tropane-2β-carboxylate benzoate (ester), 2-Methyl-3β-hydroxy-1alphah,5alphah-tropane-2β-carboxylic acid benzoic acid (ester), [1R-(exo,exo)]-3-(Benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate, methyl ester, b-Cocain, Β-cocain, Methyl [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid, (−)-cocaine, Cocaine HCL, Hydrochloride, cocaine, Cocaine hydrochloride, HCL, Cocaine, beta-cocaine, cocaine, corine
Esol Class Soluble
Functional Groups CN(C)C, COC(C)=O, cC(=O)OC
Compound Name Cocaine
Kingdom Organic compounds
Prediction Hob Swissadme 1.0
Exact Mass 303.147
Formal Charge 0.0
Monoisotopic Mass 303.147
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 303.35
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aromatic heteropolycyclic compounds
Lipinski Rule Of 5 True
Esol -3.047887381818182
Inchi InChI=1S/C17H21NO4/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11/h3-7,12-15H,8-10H2,1-2H3/t12-,13+,14-,15+/m0/s1
Smiles CN1[C@H]2CC[C@@H]1[C@H]([C@H](C2)OC(=O)C3=CC=CC=C3)C(=O)OC
Nring 3.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Taxonomy Direct Parent Benzoic acid esters
Np Classifier Superclass Ornithine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Erythroxylum Coca (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Erythroxylum Cuneatum (Plant) Rel Props:Reference:https://doi.org/10.15482/usda.adc/1239279
  • 3. Outgoing r'ship FOUND_IN to/from Erythroxylum Monogynum (Plant) Rel Props:Reference:ISBN:9788172361266
  • 4. Outgoing r'ship FOUND_IN to/from Tiliacora Racemosa (Plant) Rel Props:Reference:ISBN:9788172363130; ISBN:9788185042053