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Andrographiside

PubChem CID: 44593583

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Compound Synonyms Andrographiside, 82209-76-5, CHEMBL519275, HDA20976, HY-N2867, AKOS040761352, FS-9247, NCGC00385287-01, CS-0023446, NS00097655, (3E,4S)-3-[2-[(1R,4aS,5R,6R,8aS)-6-hydroxy-5,8a-dimethyl-2-methylidene-5-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethylidene]-4-hydroxyoxolan-2-one
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 166.0
Hydrogen Bond Donor Count 6.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CCCC1CCC1C(C)CCC2C(CCC3CCCCC3)CCCC12
Np Classifier Class Labdane diterpenoids
Deep Smiles OC[C@H]O[C@@H]OC[C@]C)[C@H]O)CC[C@@][C@@H]6CCC=C)[C@H]6C/C=C[C@H]O)COC5=O)))))))))))))C))))))))[C@@H][C@H][C@@H]6O))O))O
Heavy Atom Count 36.0
Classyfire Class Organooxygen compounds
Scaffold Graph Node Level CC1CCC2C(COC3CCCCO3)CCCC2C1CCC1CCOC1O
Classyfire Subclass Carbohydrates and carbohydrate conjugates
Isotope Atom Count 0.0
Molecular Complexity 875.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 11.0
Iupac Name (3E,4S)-3-[2-[(1R,4aS,5R,6R,8aS)-6-hydroxy-5,8a-dimethyl-2-methylidene-5-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethylidene]-4-hydroxyoxolan-2-one
Prediction Hob 0.0
Veber Rule False
Classyfire Superclass Organic oxygen compounds
Xlogp 0.0
Gsk 4 400 Rule False
Molecular Formula C26H40O10
Scaffold Graph Node Bond Level C=C1CCC2C(COC3CCCCO3)CCCC2C1CC=C1CCOC1=O
Prediction Swissadme 0.0
Inchi Key VUEPOIYXKZTLMD-ANZZXSATSA-N
Silicos It Class Soluble
Fcsp3 0.8076923076923077
Logs -2.467
Rotatable Bond Count 6.0
Logd 0.217
Synonyms andrographiside
Esol Class Soluble
Functional Groups C/C=C1CCOC1=O, C=C(C)C, CO, CO[C@@H](C)OC
Compound Name Andrographiside
Prediction Hob Swissadme 0.0
Exact Mass 512.262
Formal Charge 0.0
Monoisotopic Mass 512.262
Hydrogen Bond Acceptor Count 10.0
Molecular Weight 512.6
Gi Absorption False
Covalent Unit Count 1.0
Total Atom Stereocenter Count 11.0
Total Bond Stereocenter Count 1.0
Lipinski Rule Of 5 False
Esol -2.6346952000000012
Inchi InChI=1S/C26H40O10/c1-13-4-7-18-25(2,15(13)6-5-14-16(28)11-34-23(14)33)9-8-19(29)26(18,3)12-35-24-22(32)21(31)20(30)17(10-27)36-24/h5,15-22,24,27-32H,1,4,6-12H2,2-3H3/b14-5+/t15-,16-,17-,18+,19-,20-,21+,22-,24-,25+,26+/m1/s1
Smiles C[C@@]12CC[C@H]([C@@]([C@H]1CCC(=C)[C@H]2C/C=C/3\[C@@H](COC3=O)O)(C)CO[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O
Nring 4.0
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 1.0
Egan Rule False
Np Classifier Superclass Diterpenoids

  • 1. Outgoing r'ship FOUND_IN to/from Andrographis Paniculata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all