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Demecolcinone

PubChem CID: 44583926

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Compound Synonyms demecolcinone, (2R)-8-hydroxy-10,15-dimethoxy-4-methyl-5-azapentacyclo(10.5.0.02,5.04,6.06,11)heptadeca-1(17),7,10,12,14-pentaene-9,16-dione, (2R)-8-hydroxy-10,15-dimethoxy-4-methyl-5-azapentacyclo[10.5.0.02,5.04,6.06,11]heptadeca-1(17),7,10,12,14-pentaene-9,16-dione, CHEMBL462714, 847849-48-3
Topological Polar Surface Area 75.8
Hydrogen Bond Donor Count 1.0
Heavy Atom Count 25.0
Isotope Atom Count 0.0
Molecular Complexity 933.0
Database Name cmaup_ingredients;pubchem
Defined Atom Stereocenter Count 1.0
Iupac Name (2R)-8-hydroxy-10,15-dimethoxy-4-methyl-5-azapentacyclo[10.5.0.02,5.04,6.06,11]heptadeca-1(17),7,10,12,14-pentaene-9,16-dione
Prediction Hob 1.0
Xlogp 0.5
Molecular Formula C19H17NO5
Prediction Swissadme 0.0
Inchi Key JHQXILBWKAUJFN-VGENCSJCSA-N
Fcsp3 0.3684210526315789
Logs -4.422
Rotatable Bond Count 2.0
Logd 1.281
Compound Name Demecolcinone
Prediction Hob Swissadme 0.0
Exact Mass 339.111
Formal Charge 0.0
Monoisotopic Mass 339.111
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 339.3
Covalent Unit Count 1.0
Total Atom Stereocenter Count 3.0
Total Bond Stereocenter Count 0.0
Esol 0.31814859999999945
Inchi InChI=1S/C19H17NO5/c1-18-7-11-10-6-12(21)14(24-2)5-4-9(10)15-17(25-3)16(23)13(22)8-19(15,18)20(11)18/h4-6,8,11,22H,7H2,1-3H3/t11-,18?,19?,20?/m1/s1
Smiles CC12C[C@H]3N1C24C=C(C(=O)C(=C4C5=CC=C(C(=O)C=C35)OC)OC)O
Nring 5.0
Defined Bond Stereocenter Count 0.0