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Trenudine

PubChem CID: 44559314

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Compound Synonyms TRENUDINE, (1S,2S,4S,5R,6S,10S,11R,12E,14E)-20-chloro-10,24,25-trihydroxy-11,16,19-trimethoxy-2,5,15,25,28-pentamethyl-3,7,30-trioxa-9,22,27-triazapentacyclo(20.8.2.16,10.117,21.02,4)tetratriaconta-12,14,17(33),18,20-pentaene-8,26,29,32-tetrone, (1S,2S,4S,5R,6S,10S,11R,12E,14E)-20-chloro-10,24,25-trihydroxy-11,16,19-trimethoxy-2,5,15,25,28-pentamethyl-3,7,30-trioxa-9,22,27-triazapentacyclo[20.8.2.16,10.117,21.02,4]tetratriaconta-12,14,17(33),18,20-pentaene-8,26,29,32-tetrone, CHEMBL502969
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 215.0
Hydrogen Bond Donor Count 5.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CCCC2C(C)CC(CC(C)CC1)C1CC1CC1CC(C)CC(CCCCCCC3CCCC2C3)C1
Np Classifier Class Ansa macrolides
Deep Smiles CO[C@@H]/C=C/C=CC)/COC))cccOC))ccc6)NC=O)C[C@@H][C@][C@H][C@@H][C@@H]C[C@@]%21O)NC=O)O6))))))C))O3))C))OC=O)CC)NC=O)CCC%12)O))C)O))))))))))))Cl
Heavy Atom Count 53.0
Classyfire Class Peptidomimetics
Scaffold Graph Node Level OC1CCCN2C(O)CC(OC(O)CN1)C1OC1CC1CC(CCCCCCC3CCCC2C3)NC(O)O1
Classyfire Subclass Depsipeptides
Isotope Atom Count 0.0
Molecular Complexity 1480.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 7.0
Iupac Name (1S,2S,4S,5R,6S,10S,11R,12E,14E)-20-chloro-10,24,25-trihydroxy-11,16,19-trimethoxy-2,5,15,25,28-pentamethyl-3,7,30-trioxa-9,22,27-triazapentacyclo[20.8.2.16,10.117,21.02,4]tetratriaconta-12,14,17(33),18,20-pentaene-8,26,29,32-tetrone
Veber Rule False
Classyfire Superclass Organic acids and derivatives
Xlogp 0.9
Gsk 4 400 Rule False
Molecular Formula C36H48ClN3O13
Scaffold Graph Node Bond Level O=C1CCCN2C(=O)CC(OC(=O)CN1)C1OC1CC1CC(CC=CC=CCc3cccc2c3)NC(=O)O1
Inchi Key SEGCAWMBEYYQNG-ASTJGFRCSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 3.0
Synonyms trenudine
Esol Class Moderately soluble
Functional Groups C/C(C)=C/C=C/C, CC(=O)OC, CNC(C)=O, CO, COC, C[C@@]1(C)O[C@H]1C, C[C@@]1(O)CCOC(=O)N1, cCl, cN(C)C(C)=O, cOC
Compound Name Trenudine
Exact Mass 765.288
Formal Charge 0.0
Monoisotopic Mass 765.288
Hydrogen Bond Acceptor Count 13.0
Molecular Weight 766.2
Gi Absorption False
Covalent Unit Count 1.0
Total Atom Stereocenter Count 11.0
Total Bond Stereocenter Count 2.0
Lipinski Rule Of 5 False
Inchi InChI=1S/C36H48ClN3O13/c1-17-10-9-11-25(49-7)36(47)15-23(51-33(45)39-36)18(2)30-35(5,53-30)26-14-27(42)40(21-12-20(29(17)50-8)13-22(48-6)28(21)37)16-24(41)34(4,46)32(44)38-19(3)31(43)52-26/h9-13,18-19,23-26,29-30,41,46-47H,14-16H2,1-8H3,(H,38,44)(H,39,45)/b11-9+,17-10+/t18-,19?,23+,24?,25-,26+,29?,30+,34?,35+,36+/m1/s1
Smiles C[C@@H]1[C@@H]2C[C@]([C@@H](/C=C/C=C(/C(C3=CC(=C(C(=C3)OC)Cl)N4CC(C(C(=O)NC(C(=O)O[C@@H](CC4=O)[C@]5([C@H]1O5)C)C)(C)O)O)OC)\C)OC)(NC(=O)O2)O
Np Classifier Biosynthetic Pathway Polyketides
Defined Bond Stereocenter Count 2.0
Egan Rule False
Np Classifier Superclass Macrolides

  • 1. Outgoing r'ship FOUND_IN to/from Mallotus Repandus (Plant) Rel Props:Reference:ISBN:9788172360818; ISBN:9788185042114