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Demethyltrewiasine

PubChem CID: 44559312

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Compound Synonyms Demethyltrewiasine, CHEMBL452377
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 174.0
Hydrogen Bond Donor Count 3.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CCC2CC2CC2CC(C)CC(CCCCCCC3CCCC(C1)C3)C2
Np Classifier Class Ansa macrolides
Deep Smiles COC/C=C/C=C/[C@@H]OC))[C@]O)NC=O)O[C@@H]C6)[C@H][C@H][C@@][C@H]CC=O)Nccc%21ccOC))c6Cl)))))))C))))OC=O)[C@@H]NC=O)CC)C))))C)))))C)O3)))C)))))))))))/C
Heavy Atom Count 51.0
Classyfire Class Macrolactams
Scaffold Graph Node Level OC1CCC2OC2CC2CC(CCCCCCC3CCCC(C3)N1)NC(O)O2
Isotope Atom Count 0.0
Molecular Complexity 1360.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 8.0
Iupac Name [(1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,15,20-trimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl] (2S)-2-(2-methylpropanoylamino)propanoate
Veber Rule False
Classyfire Superclass Phenylpropanoids and polyketides
Xlogp 2.3
Gsk 4 400 Rule False
Molecular Formula C36H50ClN3O11
Scaffold Graph Node Bond Level O=C1CCC2OC2CC2CC(CC=CC=CCc3cccc(c3)N1)NC(=O)O2
Inchi Key ZOEMEKDIPYTCFY-CLIJUWRQSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 8.0
Synonyms demethyltrewiasine
Esol Class Moderately soluble
Functional Groups C/C(C)=C/C=C/C, CC(=O)NC, COC, COC(C)=O, C[C@@]1(C)O[C@H]1C, C[C@@]1(O)CCOC(=O)N1, cCl, cN(C)C(C)=O, cOC
Compound Name Demethyltrewiasine
Exact Mass 735.313
Formal Charge 0.0
Monoisotopic Mass 735.313
Hydrogen Bond Acceptor Count 11.0
Molecular Weight 736.2
Gi Absorption False
Covalent Unit Count 1.0
Total Atom Stereocenter Count 9.0
Total Bond Stereocenter Count 2.0
Lipinski Rule Of 5 False
Inchi InChI=1S/C36H50ClN3O11/c1-18(2)32(42)38-21(5)33(43)50-27-16-28(41)40(7)23-14-22(15-24(46-8)29(23)37)30(48-10)19(3)12-11-13-26(47-9)36(45)17-25(49-34(44)39-36)20(4)31-35(27,6)51-31/h11-15,18,20-21,25-27,30-31,45H,16-17H2,1-10H3,(H,38,42)(H,39,44)/b13-11+,19-12+/t20-,21+,25+,26-,27+,30?,31+,35+,36+/m1/s1
Smiles C[C@@H]1[C@@H]2C[C@]([C@@H](/C=C/C=C(/C(C3=CC(=C(C(=C3)OC)Cl)N(C(=O)C[C@@H]([C@]4([C@H]1O4)C)OC(=O)[C@H](C)NC(=O)C(C)C)C)OC)\C)OC)(NC(=O)O2)O
Np Classifier Biosynthetic Pathway Polyketides
Defined Bond Stereocenter Count 2.0
Egan Rule False
Np Classifier Superclass Macrolides

  • 1. Outgoing r'ship FOUND_IN to/from Mallotus Repandus (Plant) Rel Props:Reference:ISBN:9788185042114