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3-O-ethyl 5-O-[(2S,3R,7R,9S,10R)-4-methyl-12-oxo-11,16,18-trioxa-4-azapentacyclo[11.7.0.02,10.03,7.015,19]icosa-1(20),13,15(19)-trien-9-yl] 2,6-dimethylpyridine-3,5-dicarboxylate

PubChem CID: 44559310

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Compound Synonyms CHEMBL448553
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 113.0
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC(CC1CC2CCCC2C2C1CC(C)C1CC3CCCC3CC12)C1CCCCC1
Deep Smiles CCOC=O)cccC=O)O[C@H]C[C@H]CCN[C@H]5[C@H][C@H]9OC=O)cc6cccc6)OCO5)))))))))))))C)))))))))cnc6C)))C
Heavy Atom Count 38.0
Classyfire Class Amaryllidaceae alkaloids
Scaffold Graph Node Level OC(OC1CC2CCNC2C2C3CC4OCOC4CC3C(O)OC12)C1CCCNC1
Classyfire Subclass Homolycorine-type amaryllidaceae alkaloids
Isotope Atom Count 0.0
Molecular Complexity 946.0
Database Name imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 5.0
Iupac Name 3-O-ethyl 5-O-[(2S,3R,7R,9S,10R)-4-methyl-12-oxo-11,16,18-trioxa-4-azapentacyclo[11.7.0.02,10.03,7.015,19]icosa-1(20),13,15(19)-trien-9-yl] 2,6-dimethylpyridine-3,5-dicarboxylate
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 3.7
Gsk 4 400 Rule False
Molecular Formula C28H30N2O8
Scaffold Graph Node Bond Level O=C(OC1CC2CCNC2C2c3cc4c(cc3C(=O)OC12)OCO4)c1cccnc1
Inchi Key CIGBOXJOIYMZFE-ARIYCVRESA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 6.0
Synonyms cliviamartine
Esol Class Moderately soluble
Functional Groups CN(C)C, c1cOCO1, cC(=O)OC, cnc
Compound Name 3-O-ethyl 5-O-[(2S,3R,7R,9S,10R)-4-methyl-12-oxo-11,16,18-trioxa-4-azapentacyclo[11.7.0.02,10.03,7.015,19]icosa-1(20),13,15(19)-trien-9-yl] 2,6-dimethylpyridine-3,5-dicarboxylate
Exact Mass 522.2
Formal Charge 0.0
Monoisotopic Mass 522.2
Hydrogen Bond Acceptor Count 10.0
Molecular Weight 522.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 5.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C28H30N2O8/c1-5-34-26(31)16-9-17(14(3)29-13(16)2)27(32)37-22-8-15-6-7-30(4)24(15)23-18-10-20-21(36-12-35-20)11-19(18)28(33)38-25(22)23/h9-11,15,22-25H,5-8,12H2,1-4H3/t15-,22+,23+,24-,25+/m1/s1
Smiles CCOC(=O)C1=CC(=C(N=C1C)C)C(=O)O[C@H]2C[C@H]3CCN([C@H]3[C@H]4[C@H]2OC(=O)C5=CC6=C(C=C45)OCO6)C
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Clivia Miniata (Plant) Rel Props:Source_db:npass_chem_all