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Sanguinine

PubChem CID: 443722

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Compound Synonyms Sanguinine, O-Desmethyl Galanthamine, 60755-80-8, O-Desmethylgalantamine, O-DESMETHYLGALANTHAMINE, O-Desmethyl Galantamine, UNII-L7ZOW3CZ7W, L7ZOW3CZ7W, CHEMBL1524, (1S,12S,14R)-4-methyl-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraene-9,14-diol, CHEBI:32117, GALANTAMINE METABOLITE M6, GALANTHAMINE, O-DEMETHYL-, DTXSID40209575, 6H-BENZOFURO(3A,3,2-EF)(2)BENZAZEPINE-3,6-DIOL, 4A,5,9,10,11,12-HEXAHYDRO-11-METHYL-, (4AS,6R,8AS)-, O-Demethylgalanthamine, GALANTAMINE HYDROBROMIDE IMPURITY, O-DESMETHYLGALANTAMINE-(USP IMPURITY), GALANTAMINE HYDROBROMIDE IMPURITY, O-DESMETHYLGALANTAMINE-[USP IMPURITY], (1S,12S,14R)-4-methyl-11-oxa-4-azatetracyclo(8.6.1.01,12.06,17)heptadeca-6(17),7,9,15-tetraene-9,14-diol, 6-O-demethylgalantamine, SCHEMBL10440905, DTXCID90132066, ARD193991, BDBM50221070, AKOS030242530, (4aS,6R,8aS)-11-Methyl-5,6,9,10,11,12-hexahydro-4aH-[1]benzofuro[3a,3,2-ef][2]benzazepine-3,6-diol, (4aS,6R,8aS)-4a,5,9,10,11,12-Hexahydro-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepine-3,6-diol, 10-Methyl-galantham-1-ene-3beta,6-diol, MS-23882, DB-257731, HY-131413, CS-0134267, NS00116193, O-DESMETHYLGALANTAMINE [USP IMPURITY], F82739, Q27114789, (1S,12S,14R)-4-methyl-11-oxa-4-azatetracyclo[8.6.1.0?,??.0?,??]heptadeca-6(17),7,9,15-tetraene-9,14-diol, (4aS,6R,8aS)-4a,5,9,10,11,12-Hexahydro-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepine-3,6-diol, 10-Methyl-galantham-1-ene-3b,6-diol, Sanguinine
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 52.9
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC23CCCCC2CC2CCCC(C1)C23
Np Classifier Class Amarylidaceae alkaloids
Deep Smiles O[C@H]C=C[C@][C@H]C6)Occ5cccc6O))))CNCC%10))C
Heavy Atom Count 20.0
Classyfire Class Amaryllidaceae alkaloids
Scaffold Graph Node Level C1CC2CNCCC34CCCCC3OC(C1)C24
Classyfire Subclass Galanthamine-type amaryllidaceae alkaloids
Isotope Atom Count 0.0
Molecular Complexity 426.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 3.0
Uniprot Id P22303
Iupac Name (1S,12S,14R)-4-methyl-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraene-9,14-diol
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Target Id NPT204
Xlogp 1.5
Gsk 4 400 Rule True
Molecular Formula C16H19NO3
Scaffold Graph Node Bond Level C1=CC23CCNCc4cccc(c42)OC3CC1
Prediction Swissadme 0.0
Inchi Key OYSGWKOGUVOGFQ-RBOXIYTFSA-N
Silicos It Class Soluble
Fcsp3 0.5
Logs -1.655
Rotatable Bond Count 0.0
Logd 0.508
Synonyms sanguinine
Esol Class Soluble
Functional Groups CC=CC, CN(C)C, CO, cO, cOC
Compound Name Sanguinine
Prediction Hob Swissadme 0.0
Exact Mass 273.136
Formal Charge 0.0
Monoisotopic Mass 273.136
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 273.33
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 3.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -2.7079584000000003
Inchi InChI=1S/C16H19NO3/c1-17-7-6-16-5-4-11(18)8-13(16)20-15-12(19)3-2-10(9-17)14(15)16/h2-5,11,13,18-19H,6-9H2,1H3/t11-,13-,16-/m0/s1
Smiles CN1CC[C@@]23C=C[C@@H](C[C@@H]2OC4=C(C=CC(=C34)C1)O)O
Nring 4.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Aralia Subcapitata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Leucojum Aestivum (Plant) Rel Props:Reference:ISBN:9788172362461
  • 3. Outgoing r'ship FOUND_IN to/from Pittosporum Eugenioides (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Pteroxygonum Giraldii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Scadoxus Multiflorus (Plant) Rel Props:Reference:ISBN:9788185042138
  • 6. Outgoing r'ship FOUND_IN to/from Zephyranthes Candida (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all