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Hydroxysanguinarine

PubChem CID: 443716

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Compound Synonyms Hydroxysanguinarine, Oxysanguinarine, 548-30-1, 13-Methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridine-14(13H)-one, 13-Methyl-[1,3]dioxolo[4',5':4,5]benzo[1,2-c][1,3]dioxolo[4,5-i]phenanthridin-14(13H)-one, 24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.02,10.04,8.014,22.017,21]tetracosa-1(13),2,4(8),9,11,14(22),15,17(21)-octaen-23-one, C12222, dicyanide, AC1L9F22, CHEMBL4785846, CHEBI:31679, DTXSID80203274, AAA54830, HY-N7642, AKOS040760613, FS-7203, CS-0134941, G69187, Q27114637, (1,3)Benzodioxolo(5,6-c)-1,3-dioxolo(4,5-i)phenanthridin-14(13H)-one, 13-methyl-
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 57.2
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CC2C3CC4CCCC4CC3CCC2C2CCC3CCCC3C12
Np Classifier Class Isoquinoline alkaloids
Deep Smiles Cnc=O)ccOCOc5ccc9cc%13cccOCOc5cc9cc%13
Heavy Atom Count 26.0
Classyfire Class Quinolines and derivatives
Scaffold Graph Node Level OC1NC2C3CC4OCOC4CC3CCC2C2CCC3OCOC3C12
Classyfire Subclass Benzoquinolines
Isotope Atom Count 0.0
Molecular Complexity 599.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name 24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.02,10.04,8.014,22.017,21]tetracosa-1(13),2,4(8),9,11,14(22),15,17(21)-octaen-23-one
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 3.5
Gsk 4 400 Rule True
Molecular Formula C20H13NO5
Scaffold Graph Node Bond Level O=c1[nH]c2c3cc4c(cc3ccc2c2ccc3c(c12)OCO3)OCO4
Prediction Swissadme 0.0
Inchi Key UFHGABBBZRPRJV-UHFFFAOYSA-N
Silicos It Class Moderately soluble
Fcsp3 0.15
Logs -8.076
Rotatable Bond Count 0.0
Logd 3.474
Synonyms oxysanguinarine
Esol Class Moderately soluble
Functional Groups c1cOCO1, c=O, cn(c)C
Compound Name Hydroxysanguinarine
Prediction Hob Swissadme 0.0
Exact Mass 347.079
Formal Charge 0.0
Monoisotopic Mass 347.079
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 347.3
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -5.643128892307693
Inchi InChI=1S/C20H13NO5/c1-21-18-12(3-2-10-6-15-16(7-13(10)18)25-8-24-15)11-4-5-14-19(26-9-23-14)17(11)20(21)22/h2-7H,8-9H2,1H3
Smiles CN1C2=C(C=CC3=CC4=C(C=C32)OCO4)C5=C(C1=O)C6=C(C=C5)OCO6
Nring 6.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Aloe Microstigma (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Artocarpus Lakoocha (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Chelidonium Majus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Chrozophora Prostrata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Corydalis Pallida (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Dicranostigma Lactucoides (Plant) Rel Props:Reference:ISBN:9788185042053
  • 7. Outgoing r'ship FOUND_IN to/from Fumaria Indica (Plant) Rel Props:Reference:ISBN:9788171360536
  • 8. Outgoing r'ship FOUND_IN to/from Fumaria Vaillantii (Plant) Rel Props:Reference:ISBN:9788172363130; ISBN:9788185042114
  • 9. Outgoing r'ship FOUND_IN to/from Macleaya Cordata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 10. Outgoing r'ship FOUND_IN to/from Maclura Pomifera (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 11. Outgoing r'ship FOUND_IN to/from Morus Alba (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 12. Outgoing r'ship FOUND_IN to/from Papaver Somniferum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 13. Outgoing r'ship FOUND_IN to/from Veratrum Grandiflorum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all