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(E)-N-[(2S,3S,4R,8R,9S,10R,13R,17S)-17-[(1S)-1-(dimethylamino)ethyl]-2,4-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]-2-methylbut-2-enamide

PubChem CID: 44358199

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Compound Synonyms CHEMBL337494, BDBM50421629
Topological Polar Surface Area 72.8
Hydrogen Bond Donor Count 3.0
Heavy Atom Count 33.0
Isotope Atom Count 0.0
Molecular Complexity 835.0
Database Name cmaup_ingredients;npass_chem_all;pubchem
Defined Atom Stereocenter Count 9.0
Uniprot Id P22303
Iupac Name (E)-N-[(2S,3S,4R,8R,9S,10R,13R,17S)-17-[(1S)-1-(dimethylamino)ethyl]-2,4-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]-2-methylbut-2-enamide
Prediction Hob 0.0
Target Id NPT204
Xlogp 4.2
Molecular Formula C28H46N2O3
Prediction Swissadme 1.0
Inchi Key QVNOTNUGUHMPDI-AIWDQZKNSA-N
Fcsp3 0.8214285714285714
Logs -4.084
Rotatable Bond Count 4.0
Logd 3.358
Compound Name (E)-N-[(2S,3S,4R,8R,9S,10R,13R,17S)-17-[(1S)-1-(dimethylamino)ethyl]-2,4-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]-2-methylbut-2-enamide
Prediction Hob Swissadme 0.0
Exact Mass 458.351
Formal Charge 0.0
Monoisotopic Mass 458.351
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 458.7
Covalent Unit Count 1.0
Total Atom Stereocenter Count 10.0
Total Bond Stereocenter Count 1.0
Esol -5.012459400000001
Inchi InChI=1S/C28H46N2O3/c1-8-16(2)26(33)29-24-23(31)15-28(5)21-13-14-27(4)19(17(3)30(6)7)11-12-20(27)18(21)9-10-22(28)25(24)32/h8,12,17-19,21-25,31-32H,9-11,13-15H2,1-7H3,(H,29,33)/b16-8+/t17-,18-,19+,21-,22?,23-,24-,25+,27+,28+/m0/s1
Smiles C/C=C(\C)/C(=O)N[C@H]1[C@H](C[C@@]2([C@H]3CC[C@@]4([C@H](CC=C4[C@@H]3CCC2[C@H]1O)[C@H](C)N(C)C)C)C)O
Nring 4.0
Defined Bond Stereocenter Count 1.0