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(E)-N-[(3S,8S,9S,10R,13S,14S,17S)-17-[(1S)-1-(dimethylamino)ethyl]-10,13-dimethyl-4-oxo-1,2,3,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-yl]-2-methylbut-2-enamide

PubChem CID: 44358068

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Compound Synonyms CHEMBL343780, BDBM50135158, (E)-2-Methyl-but-2-enoic acid [(3S,8S,9S,10R,13S,14S,17S)-17-((S)-1-dimethylamino-ethyl)-10,13-dimethyl-4-oxo-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl]-amide
Topological Polar Surface Area 49.4
Hydrogen Bond Donor Count 1.0
Heavy Atom Count 32.0
Isotope Atom Count 0.0
Molecular Complexity 842.0
Database Name cmaup_ingredients;npass_chem_all;pubchem
Defined Atom Stereocenter Count 8.0
Uniprot Id P04058, P06276, P22303
Iupac Name (E)-N-[(3S,8S,9S,10R,13S,14S,17S)-17-[(1S)-1-(dimethylamino)ethyl]-10,13-dimethyl-4-oxo-1,2,3,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-yl]-2-methylbut-2-enamide
Prediction Hob 0.0
Target Id NPT439, NPT204
Xlogp 6.0
Molecular Formula C28H44N2O2
Prediction Swissadme 0.0
Inchi Key HZOTXNIDOKRKQY-KQFGCDFKSA-N
Fcsp3 0.7857142857142857
Logs -4.864
Rotatable Bond Count 4.0
Logd 4.268
Compound Name (E)-N-[(3S,8S,9S,10R,13S,14S,17S)-17-[(1S)-1-(dimethylamino)ethyl]-10,13-dimethyl-4-oxo-1,2,3,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-yl]-2-methylbut-2-enamide
Prediction Hob Swissadme 0.0
Exact Mass 440.34
Formal Charge 0.0
Monoisotopic Mass 440.34
Hydrogen Bond Acceptor Count 3.0
Molecular Weight 440.7
Covalent Unit Count 1.0
Total Atom Stereocenter Count 8.0
Total Bond Stereocenter Count 1.0
Esol -6.396866400000001
Inchi InChI=1S/C28H44N2O2/c1-8-17(2)26(32)29-24-14-16-28(5)22-13-15-27(4)20(18(3)30(6)7)11-12-21(27)19(22)9-10-23(28)25(24)31/h8,10,18-22,24H,9,11-16H2,1-7H3,(H,29,32)/b17-8+/t18-,19-,20+,21-,22-,24-,27+,28+/m0/s1
Smiles C/C=C(\C)/C(=O)N[C@H]1CC[C@@]2([C@H]3CC[C@]4([C@H]([C@@H]3CC=C2C1=O)CC[C@@H]4[C@H](C)N(C)C)C)C
Nring 4.0
Defined Bond Stereocenter Count 1.0