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16-Methoxytabersonine

PubChem CID: 443356

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Compound Synonyms Ervamycine, 16-Methoxytabersonine, 27773-39-3, 11-Methoxytabersonine, CHEBI:769, methyl (1R,12R,19S)-12-ethyl-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2(7),3,5,9,13-pentaene-10-carboxylate, methyl 16-methoxy-2,3,6,7-tetradehydro-5alpha,12beta,19alpha-aspidospermidine-3-carboxylate, 1-methoxytabersonine, 16-methoxy-tabersonine, (-)-11-Methoxytabersonine, VX294XSR6T, (-)-11-Methoxytabersonine, 11-Methoxytabersonine, 16-Methoxytabersonine, CHEMBL1165751, DTXSID301032205, Aspidospermidine-3-carboxylic acid, 2,3,6,7-tetradehydro-16-methoxy-, methyl ester, (5alpha,12R,19alpha)-, HY-N3849, AKOS032962272, FS-9706, DA-52992, XE172909, CS-0024329, NS00094509, Q21099580, ASPIDOSPERMIDINE-3-CARBOXYLIC ACID, 2,3,6,7-TETRADEHYDRO-16-METHOXY-, METHYL ESTER, (5.ALPHA.,12R,19.ALPHA.)-, Methyl(5alpha,12beta,19alpha)-16-methoxy-2,3,6,7-tetradehydroaspidospermidine-3-carboxylate
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 50.8
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CC1CCC3CCCC4CCC12C34
Np Classifier Class Aspidosperma type
Deep Smiles COcccccc6)NC=CC[C@][C@H][C@@]96CCN5CC=C9))))))))CC))))C=O)OC
Heavy Atom Count 27.0
Classyfire Class Plumeran-type alkaloids
Scaffold Graph Node Level C1CCC2C(C1)NC1CCC3CCCN4CCC12C34
Isotope Atom Count 0.0
Molecular Complexity 716.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 3.0
Iupac Name methyl (1R,12R,19S)-12-ethyl-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2(7),3,5,9,13-pentaene-10-carboxylate
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 3.3
Gsk 4 400 Rule True
Molecular Formula C22H26N2O3
Scaffold Graph Node Bond Level C1=CC2CC=C3Nc4ccccc4C34CCN(C1)C24
Prediction Swissadme 1.0
Inchi Key AEXBRBWRPNGGEZ-FKBYEOEOSA-N
Silicos It Class Moderately soluble
Fcsp3 0.5
Logs -3.993
Rotatable Bond Count 4.0
Logd 2.339
Synonyms 11-methoxytabersonine, 16-methoxytabersonine
Esol Class Moderately soluble
Functional Groups CC=CC, CN(C)C, cNC(C)=C(C)C(=O)OC, cOC
Compound Name 16-Methoxytabersonine
Prediction Hob Swissadme 1.0
Exact Mass 366.194
Formal Charge 0.0
Monoisotopic Mass 366.194
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 366.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 3.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -4.116702644444445
Inchi InChI=1S/C22H26N2O3/c1-4-21-8-5-10-24-11-9-22(20(21)24)16-7-6-14(26-2)12-17(16)23-18(22)15(13-21)19(25)27-3/h5-8,12,20,23H,4,9-11,13H2,1-3H3/t20-,21-,22-/m0/s1
Smiles CC[C@]12CC(=C3[C@@]4([C@H]1N(CC4)CC=C2)C5=C(N3)C=C(C=C5)OC)C(=O)OC
Nring 5.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Catharanthus Roseus (Plant) Rel Props:Reference:https://doi.org/10.1093/database/bav075
  • 2. Outgoing r'ship FOUND_IN to/from Melodinus Tenuicaudatus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all