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Solasodine

PubChem CID: 442985

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Compound Synonyms solasodine, 126-17-0, Purapuridine, Solanearpidine, Solasodin, (-)-Solasodine, Solancarpidine, SOLASADINE, CHEBI:9190, Solanidine-S, SOLASODINE [MI], Solasod-5-en-3beta-ol, Solasod-5-en-3-beta-ol, L40Y453Y96, SOLASODINE [WHO-DD], (3beta,22alpha,25R)-spirosol-5-en-3-ol, UNII-L40Y453Y96, HSDB 3538, EINECS 204-774-2, NSC 178260, NSC 179187, NSC-178260, BRN 0094578, (25R)-22alpha-spirosol-5-en-3beta-ol, Spirosol-5-en-3-ol, (3beta,22alpha,25R)-, solassodine, 4-27-00-02000 (Beilstein Handbook Reference), Spirosol-5-en-3-ol, (3.beta.,22.alpha.,25R)-, (3.BETA.,22.ALPHA.,25R)-SPIROSOL-5-EN-3-OL, delta5-20Betaf,22alphaf,25alphaf,27-azaspirosten-3beta-ol, spiro[8h-naphth[2',1':4,5]indeno[2,1-b]furan-8,2'-piperidine], NSC-179187, solasodine, (3beta,22beta,25S)-isomer, (1S,2S,4S,5'R,6R,7S,8R,9S,12S,13R,16S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-piperidine]-16-ol, (2S,2'R,4aR,4bS,5'R,6aS,6bR,7S,9aS,10aS,10bS)-4a,5',6a,7-tetramethyl-1,2,3,4,4a,4b,5,6,6a,6b,7,9a,10,10a,10b,11-hexadecahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-8,2'-piperidin]-2-ol, (4S,5'R,6aR,6bS,8aS,8bR,9S,10R,11aS,12aS,12bS)-5',6a,8a,9-Tetramethyl-1,3,4,5,6,6a,6b,7,8,8a,8b,9,11a,12,12a,12b-hexadecahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-piperidin]-4-ol, 5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-piperidine]-16-ol, Solasod-5-en-3.beta.-ol, SR-01000814832, SolanidineS, SOLASODINE HYDROCHLORIDE BASE, Purapuridine, Solancarpidine, Solasodin, Spiro(8H-naphth(2',1':4,5)indeno(2,1-b)furan-8,2'-piperidine), NSC178260, Solasod5en3betaol, (1S,2S,4S,5'R,6R,7S,8R,9S,12S,13R,16S)-5',7,9,13-tetramethylspiro(5-oxapentacyclo(10.8.0.02,9.04,8.013,18)icos-18-ene-6,2'-piperidine)-16-ol, (2S,2'R,4aR,4bS,5'R,6aS,6bR,7S,9aS,10aS,10bS)-4a,5',6a,7-tetramethyl-1,2,3,4,4a,4b,5,6,6a,6b,7,9a,10,10a,10b,11-hexadecahydrospiro(naphtho(2',1':4,5)indeno(2,1-b)furan-8,2'-piperidin)-2-ol, 5',7,9,13-tetramethylspiro(5-oxapentacyclo(10.8.0.02,9.04,8.013,18)icos-18-ene-6,2'-piperidine)-16-ol, Spiro(8H-naphth(2',1':4,5)indeno(2,1-b)furan-8,2'-piperidine), spirosol-5-en-3-ol deriv., Spiro[8H-naphth[2',1':4,5]indeno[2,1-b]furan-8,2'-piperidine], spirosol-5-en-3-ol deriv., Solasod-5-en-3b-ol, Solasod-5-en-3I2-ol, Prestwick3_000663, solasodine citrate, (3alpha,22alpha,25R)-isomer, BSPBio_000725, MLS001164064, SCHEMBL456185, BPBio1_000799, CHEMBL518252, Solasodine - Bio-X trade mark, KWVISVAMQJWJSZ-VKROHFNGSA-N, DTXSID101030558, HMS2097E07, HMS2862C06, HY-N0068, MFCD00037844, AKOS015969707, CS-1651, OS73940, (3b,22a,25R)-Spirosol-5-en-3-ol, NCGC00179461-01, Spirosol5en3ol, (3beta,22alpha,25R), BS300158, SMR000539436, AB00513879, NS00041398, Q740439, SR-01000814832-3, SR-01000814832-4, Spirosol-5-en-3-ol, (3beta,22alpha,25R)-(9CI), delta520betaf,22alphaf,25alphaf,27Azaspirosten3betaol, 204-774-2, 38675-34-2
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 41.5
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2(CC1)CC1CC3C(CCC4C5CCCCC5CCC43)C1C2
Np Classifier Class Steroidal alkaloids
Deep Smiles C[C@@H]CC[C@@]NC6))O[C@@H][C@H][C@@H]5C))[C@@][C@@H]C5)[C@@H]CC=C[C@][C@H]6CC%10)))C)CC[C@@H]C6)O))))))))))C
Heavy Atom Count 30.0
Classyfire Class Steroids and steroid derivatives
Scaffold Graph Node Level C1CCC2(CC3C(CC4C3CCC3C5CCCCC5CCC34)O2)NC1
Classyfire Subclass Steroidal alkaloids
Isotope Atom Count 0.0
Molecular Complexity 749.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 11.0
Uniprot Id P04637, C4YTQ8, B9W6M3, P27695, n.a.
Iupac Name (1S,2S,4S,5'R,6R,7S,8R,9S,12S,13R,16S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-piperidine]-16-ol
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Lipids and lipid-like molecules
Xlogp 5.4
Gsk 4 400 Rule False
Molecular Formula C27H43NO2
Scaffold Graph Node Bond Level C1=C2CCCCC2C2CCC3C4CC5(CCCCN5)OC4CC3C2C1
Prediction Swissadme 0.0
Inchi Key KWVISVAMQJWJSZ-VKROHFNGSA-N
Silicos It Class Moderately soluble
Fcsp3 0.925925925925926
Logs -4.895
Rotatable Bond Count 0.0
Logd 4.373
Synonyms alpha-solanigrine, solasodin, solasodine
Esol Class Moderately soluble
Functional Groups CC=C(C)C, CN[C@@](C)(C)OC, CO
Compound Name Solasodine
Prediction Hob Swissadme 0.0
Exact Mass 413.329
Formal Charge 0.0
Monoisotopic Mass 413.329
Hydrogen Bond Acceptor Count 3.0
Molecular Weight 413.6
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 11.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -5.800305200000001
Inchi InChI=1S/C27H43NO2/c1-16-7-12-27(28-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(29)8-10-25(18,3)21(20)9-11-26(22,24)4/h5,16-17,19-24,28-29H,6-15H2,1-4H3/t16-,17+,19+,20-,21+,22+,23+,24+,25+,26+,27-/m1/s1
Smiles C[C@@H]1CC[C@@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4CC=C6[C@@]5(CC[C@@H](C6)O)C)C)C)NC1
Nring 6.0
Np Classifier Biosynthetic Pathway Alkaloids, Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Pseudoalkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Acacia Lemmoni (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Achillea Pratensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Alcea Nudiflora (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Anaphalis Margaritacea (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Angelica Sinensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Ardisia Sieboldii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 7. Outgoing r'ship FOUND_IN to/from Arum Montanum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 8. Outgoing r'ship FOUND_IN to/from Asperula Odorata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 9. Outgoing r'ship FOUND_IN to/from Boronia Lanceolata (Plant) Rel Props:Source_db:npass_chem_all
  • 10. Outgoing r'ship FOUND_IN to/from Campanula Pendula (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 11. Outgoing r'ship FOUND_IN to/from Capparis Angulata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 12. Outgoing r'ship FOUND_IN to/from Carissa Spinarum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 13. Outgoing r'ship FOUND_IN to/from Chloranthus Holostegius (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 14. Outgoing r'ship FOUND_IN to/from Chlorella Pyrenoidosa (Plant) Rel Props:Source_db:npass_chem_all
  • 15. Outgoing r'ship FOUND_IN to/from Chlorophytum Tuberosum (Plant) Rel Props:Reference:ISBN:9788171360536
  • 16. Outgoing r'ship FOUND_IN to/from Cinnamomum Pedunculatum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 17. Outgoing r'ship FOUND_IN to/from Clerodendrum Infortunatum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 18. Outgoing r'ship FOUND_IN to/from Corydalis Crystallina (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 19. Outgoing r'ship FOUND_IN to/from Cyphomandra Betacea (Plant) Rel Props:Reference:ISBN:9788172362133
  • 20. Outgoing r'ship FOUND_IN to/from Dysosma Pleiantha (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 21. Outgoing r'ship FOUND_IN to/from Eucalyptus Campanulata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 22. Outgoing r'ship FOUND_IN to/from Euphorbia Cattimandoo (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 23. Outgoing r'ship FOUND_IN to/from Hemiphragma Heterophyllum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 24. Outgoing r'ship FOUND_IN to/from Hymenocallis Rotata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 25. Outgoing r'ship FOUND_IN to/from Klaseopsis Chinensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 26. Outgoing r'ship FOUND_IN to/from Lasianthus Wallichii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 27. Outgoing r'ship FOUND_IN to/from Lomandra Hastilis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 28. Outgoing r'ship FOUND_IN to/from Mercurialis Leiocarpa (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 29. Outgoing r'ship FOUND_IN to/from Neolitsea Sericea (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 30. Outgoing r'ship FOUND_IN to/from Ochradenus Baccatus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 31. Outgoing r'ship FOUND_IN to/from Paeonia Veitchii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 32. Outgoing r'ship FOUND_IN to/from Plantago Ovata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 33. Outgoing r'ship FOUND_IN to/from Podocarpus Sellowii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 34. Outgoing r'ship FOUND_IN to/from Primula Denticulata (Plant) Rel Props:Source_db:npass_chem_all
  • 35. Outgoing r'ship FOUND_IN to/from Rabdosia Excisa (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 36. Outgoing r'ship FOUND_IN to/from Rhamnus Procumbens (Plant) Rel Props:Source_db:npass_chem_all
  • 37. Outgoing r'ship FOUND_IN to/from Rubus Foliolosus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 38. Outgoing r'ship FOUND_IN to/from Solanum Aculeatissimum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 39. Outgoing r'ship FOUND_IN to/from Solanum Americanum (Plant) Rel Props:Reference:https://doi.org/10.1002/minf.201000163
  • 40. Outgoing r'ship FOUND_IN to/from Solanum Anguivi (Plant) Rel Props:Reference:ISBN:9780387706375; ISBN:9788172361150
  • 41. Outgoing r'ship FOUND_IN to/from Solanum Aviculare (Plant) Rel Props:Reference:https://www.ncbi.nlm.nih.gov/pubmed/13948886
  • 42. Outgoing r'ship FOUND_IN to/from Solanum Dubium (Plant) Rel Props:Reference:ISBN:9788185042114
  • 43. Outgoing r'ship FOUND_IN to/from Solanum Dulcamara (Plant) Rel Props:Reference:https://www.ncbi.nlm.nih.gov/pubmed/17396951
  • 44. Outgoing r'ship FOUND_IN to/from Solanum Elaeagnifolium (Plant) Rel Props:Reference:ISBN:9780387706375
  • 45. Outgoing r'ship FOUND_IN to/from Solanum Erianthum (Plant) Rel Props:Reference:ISBN:9788185042084; ISBN:9788185042114
  • 46. Outgoing r'ship FOUND_IN to/from Solanum Ferox (Plant) Rel Props:Reference:ISBN:9788172361150
  • 47. Outgoing r'ship FOUND_IN to/from Solanum Incanum (Plant) Rel Props:Reference:ISBN:9788185042114
  • 48. Outgoing r'ship FOUND_IN to/from Solanum Kurzii (Plant) Rel Props:Reference:ISBN:9788185042145
  • 49. Outgoing r'ship FOUND_IN to/from Solanum Melongena (Plant) Rel Props:Reference:ISBN:9780387706375; ISBN:9788172361150; ISBN:9788185042053; ISBN:9788185042138; ISBN:9788185042145
  • 50. Outgoing r'ship FOUND_IN to/from Solanum Nigrum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 51. Outgoing r'ship FOUND_IN to/from Solanum Platanifolium (Plant) Rel Props:Reference:ISBN:9788185042145
  • 52. Outgoing r'ship FOUND_IN to/from Solanum Spirale (Plant) Rel Props:Reference:ISBN:9788185042138
  • 53. Outgoing r'ship FOUND_IN to/from Solanum Surattense (Plant) Rel Props:Reference:ISBN:9788172361150; ISBN:9788172363093; ISBN:9788185042145
  • 54. Outgoing r'ship FOUND_IN to/from Solanum Torvum (Plant) Rel Props:Reference:ISBN:9788185042145
  • 55. Outgoing r'ship FOUND_IN to/from Solanum Trilobatum (Plant) Rel Props:Reference:ISBN:9780387706375; ISBN:9788172361150; ISBN:9788185042145; ISBN:9789327275590
  • 56. Outgoing r'ship FOUND_IN to/from Solanum Tuberosum (Plant) Rel Props:Reference:ISBN:9788185042145
  • 57. Outgoing r'ship FOUND_IN to/from Solanum Viarum (Plant) Rel Props:Reference:ISBN:9788185042084
  • 58. Outgoing r'ship FOUND_IN to/from Solanum Virginianum (Plant) Rel Props:Reference:ISBN:9788171360536
  • 59. Outgoing r'ship FOUND_IN to/from Solanum Wrightii (Plant) Rel Props:Reference:ISBN:9788185042053
  • 60. Outgoing r'ship FOUND_IN to/from Spinacia Oleracea (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 61. Outgoing r'ship FOUND_IN to/from Teucrium Cossonii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 62. Outgoing r'ship FOUND_IN to/from Thuja Dolabrata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 63. Outgoing r'ship FOUND_IN to/from Turnera Ulmifolia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 64. Outgoing r'ship FOUND_IN to/from Vitis Labrusca (Plant) Rel Props:Source_db:npass_chem_all
  • 65. Outgoing r'ship FOUND_IN to/from Withania Somnifera (Plant) Rel Props:Reference:ISBN:9788172361150