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Sumatrol

PubChem CID: 442824

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Compound Synonyms Sumatrol, 82-10-0, (-)-sumatrol, UNII-69G1LPQ7X0, 69G1LPQ7X0, (-)-11-hydroxyrotenone, SUMATROL [MI], SUMATROL, (-)-, CHEBI:9358, DTXSID90231503, (1S,6R,13S)-10-hydroxy-16,17-dimethoxy-6-prop-1-en-2-yl-2,7,20-trioxapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),9,14,16,18-hexaen-12-one, (1)Benzopyrano(3,4-b)furo(2,3-h)(1)benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-5-hydroxy-2-isopropenyl-8,9-dimethoxy-, (-)-, (1)BENZOPYRANO(3,4-B)FURO(2,3-H)(1)BENZOPYRAN-6(6AH)-ONE, 1,2,12,12A-TETRAHYDRO-5-HYDROXY-8,9-DIMETHOXY-2-(1-METHYLETHENYL)-, (2R,6AS,12AS)-, (2R-(2.ALPHA.,6A.ALPHA.,12A.ALPHA.))-1,2,12,12A-TETRAHYDRO-5-HYDROXY-8,9-DIMETHOXY-2-(1-METHYLETHENYL)-(1)BENZOPYRANO(3,4-B)FURO(2,3-H)(1)BENZOPYRAN-6(6AH)-ONE, (1S,6R,13S)-10-hydroxy-16,17-dimethoxy-6-prop-1-en-2-yl-2,7,20-trioxapentacyclo(11.8.0.03,11.04,8.014,19)henicosa-3(11),4(8),9,14,16,18-hexaen-12-one, SpecPlus_000445, DivK1c_006541, CHEMBL518045, SCHEMBL4739987, KBio1_001485, DTXCID50153994, LMPK12060024, Q27108358, (2R-(2ALPHA,6AALPHA,12AALPHA))-1,2,12,12A-TETRAHYDRO-5-HYDROXY-8,9-DIMETHOXY-2-(1-METHYLETHENYL)-(1)BENZOPYRANO(3,4-B)FURO(2,3-H)(1)BENZOPYRAN-6(6AH)-ONE
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 83.5
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1C2CCC3CCCC3C2CC2CCC3CCCCC3C21
Np Classifier Class Isoflavanones, Rotenoids
Deep Smiles COcccOC[C@@H][C@H]c6cc%10OC)))))C=O)ccO6)cC[C@@H]Oc5cc9O)))))C=C)C
Heavy Atom Count 30.0
Classyfire Class Isoflavonoids
Scaffold Graph Node Level OC1C2CCC3OCCC3C2OC2COC3CCCCC3C21
Classyfire Subclass Rotenoids
Isotope Atom Count 0.0
Molecular Complexity 695.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 3.0
Uniprot Id P47199
Iupac Name (1S,6R,13S)-10-hydroxy-16,17-dimethoxy-6-prop-1-en-2-yl-2,7,20-trioxapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),9,14,16,18-hexaen-12-one
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Phenylpropanoids and polyketides
Xlogp 4.3
Gsk 4 400 Rule False
Molecular Formula C23H22O7
Scaffold Graph Node Bond Level O=C1c2ccc3c(c2OC2COc4ccccc4C12)CCO3
Prediction Swissadme 1.0
Inchi Key ZPEHYKMRUBEPSQ-XMCHAPAWSA-N
Silicos It Class Moderately soluble
Fcsp3 0.3478260869565217
Logs -5.536
Rotatable Bond Count 3.0
Logd 3.405
Synonyms sumatrol
Esol Class Moderately soluble
Functional Groups C=C(C)C, cC(C)=O, cO, cOC
Compound Name Sumatrol
Prediction Hob Swissadme 1.0
Exact Mass 410.137
Formal Charge 0.0
Monoisotopic Mass 410.137
Hydrogen Bond Acceptor Count 7.0
Molecular Weight 410.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 3.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -5.191616400000001
Inchi InChI=1S/C23H22O7/c1-10(2)14-6-12-16(29-14)7-13(24)21-22(25)20-11-5-17(26-3)18(27-4)8-15(11)28-9-19(20)30-23(12)21/h5,7-8,14,19-20,24H,1,6,9H2,2-4H3/t14-,19-,20+/m1/s1
Smiles CC(=C)[C@H]1CC2=C(O1)C=C(C3=C2O[C@@H]4COC5=CC(=C(C=C5[C@@H]4C3=O)OC)OC)O
Nring 5.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Isoflavonoids

  • 1. Outgoing r'ship FOUND_IN to/from Allium Macrostemon (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Crotalaria Burhia (Plant) Rel Props:Reference:ISBN:9788185042084
  • 3. Outgoing r'ship FOUND_IN to/from Crotalaria Paniculata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Derris Malaccensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Geijera Parviflora (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Indigofera Tinctoria (Plant) Rel Props:Reference:ISBN:9788172362300
  • 7. Outgoing r'ship FOUND_IN to/from Macaranga Indica (Plant) Rel Props:Reference:ISBN:9770972795006; ISBN:9788172362461
  • 8. Outgoing r'ship FOUND_IN to/from Millettia Extensa (Plant) Rel Props:Reference:ISBN:9780387706375
  • 9. Outgoing r'ship FOUND_IN to/from Piscidia Piscipula (Plant) Rel Props:Reference:ISBN:9788172362461; ISBN:9788185042053
  • 10. Outgoing r'ship FOUND_IN to/from Rubia Cordifolia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 11. Outgoing r'ship FOUND_IN to/from Spiraea Japonica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 12. Outgoing r'ship FOUND_IN to/from Tephrosia Pumila (Plant) Rel Props:Reference:ISBN:9788185042138