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Melannin

PubChem CID: 442808

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Compound Synonyms Melannin, Melanettin, 58115-08-5, 6-hydroxy-4-(4-hydroxyphenyl)-7-methoxychromen-2-one, CHEBI:6728, DTXSID50331957, 6-Hydroxy-4-(4-hydroxyphenyl)-7-methoxycoumarin, CHEMBL2397755, DTXCID80283051, LMPK12100004, Q27107313
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 76.0
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CC2CCCCC2C(C2CCCCC2)C1
Np Classifier Class Neoflavonoids
Deep Smiles COcccoc=O)ccc6cc%10O))))cccccc6))O
Heavy Atom Count 21.0
Classyfire Class Neoflavonoids
Description Constituent of the heartwood of Dalbergia melanoxylon [CCD]
Scaffold Graph Node Level OC1CC(C2CCCCC2)C2CCCCC2O1
Classyfire Subclass Neoflavones
Isotope Atom Count 0.0
Molecular Complexity 424.0
Database Name cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id n.a.
Iupac Name 6-hydroxy-4-(4-hydroxyphenyl)-7-methoxychromen-2-one
Prediction Hob 1.0
Class Neoflavonoids
Veber Rule True
Classyfire Superclass Phenylpropanoids and polyketides
Xlogp 2.3
Superclass Phenylpropanoids and polyketides
Subclass Neoflavones
Gsk 4 400 Rule True
Molecular Formula C16H12O5
Scaffold Graph Node Bond Level O=c1cc(-c2ccccc2)c2ccccc2o1
Prediction Swissadme 0.0
Inchi Key HUGUGFBIYQBLCS-UHFFFAOYSA-N
Silicos It Class Moderately soluble
Fcsp3 0.0625
Logs -3.668
Rotatable Bond Count 2.0
State Solid
Logd 2.603
Synonyms 6-Hydroxy-4-(4-hydroxyphenyl)-7-methoxycoumarin, Melannin, melanettin, melanettin [6-hydroxy-7-methoxy-4-(4- hydroxyphenyl)coumarin]
Substituent Name 4-phenylcoumarin, Hydroxycoumarin, Coumarin, 1-benzopyran, Methoxyphenol, Benzopyran, Anisole, Pyranone, Phenol, Alkyl aryl ether, Benzenoid, Pyran, Monocyclic benzene moiety, Heteroaromatic compound, Lactone, Oxacycle, Organoheterocyclic compound, Monocarboxylic acid or derivatives, Ether, Hydrocarbon derivative, Organooxygen compound, Aromatic heteropolycyclic compound
Esol Class Soluble
Functional Groups c=O, cO, cOC, coc
Compound Name Melannin
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 284.068
Formal Charge 0.0
Monoisotopic Mass 284.068
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 284.26
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aromatic heteropolycyclic compounds
Lipinski Rule Of 5 True
Esol -3.0737649238095233
Inchi InChI=1S/C16H12O5/c1-20-15-8-14-12(6-13(15)18)11(7-16(19)21-14)9-2-4-10(17)5-3-9/h2-8,17-18H,1H3
Smiles COC1=C(C=C2C(=CC(=O)OC2=C1)C3=CC=C(C=C3)O)O
Nring 3.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Taxonomy Direct Parent Neoflavones
Np Classifier Superclass Flavonoids

  • 1. Outgoing r'ship FOUND_IN to/from Arnica Longifolia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Clerodendrum Indicum (Plant) Rel Props:Source_db:npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Cuscuta Reflexa (Plant) Rel Props:Reference:ISBN:9770972795006; ISBN:9788185042145
  • 4. Outgoing r'ship FOUND_IN to/from Dalbergia Melanoxylon (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Dalbergia Odorifera (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Kaempferia Galanga (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 7. Outgoing r'ship FOUND_IN to/from Plumbago Auriculata (Plant) Rel Props:Source_db:npass_chem_all
  • 8. Outgoing r'ship FOUND_IN to/from Rubus Rigidus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all