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Rotundifolone

PubChem CID: 442497

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Compound Synonyms Rotundifolone, Piperitenone oxide, Lippione, 3564-96-3, cis-Piperitenone epoxide, Piperitenone oxide [FHFI], (+-)-Rotundifolone, FEMA No. 4199, (+-)-Piperitenone oxide, UNII-6FR5IOD112, (+)-Rotundifolone, Piperitenone oxide, (+-)-, 6FR5IOD112, (1S,6S)-6-methyl-3-propan-2-ylidene-7-oxabicyclo[4.1.0]heptan-2-one, 7-Oxabicyclo(4.1.0)heptan-2-one, 6-methyl-3-(1-methylethylidene)-, (1S)-, 7-Oxabicyclo(4.1.0)heptan-2-one, 6-methyl-3-(1-methylethylidene)-, (1S,6S)-, (1S,6S)-3-isopropylidene-6-methyl-7-oxabicyclo(4.1.0)heptan-2-one, (1S,6S)-3-isopropylidene-6-methyl-7-oxabicyclo[4.1.0]heptan-2-one, (1S,6S)-6-methyl-3-propan-2-ylidene-7-oxabicyclo(4.1.0)heptan-2-one, CHEBI:8900, SCHEMBL2317471, (+)-PIPERITENONE OXIDE, DTXSID301317536, PIPERITENONE OXIDE, (+)-, AKOS040753565, HY-134013, CS-0136507, C09896, Q27108176
Topological Polar Surface Area 29.6
Hydrogen Bond Donor Count 0.0
Heavy Atom Count 12.0
Description (+)-rotundifolone, also known as lippione, is a member of the class of compounds known as oxepanes. Oxepanes are compounds containing an oxepane ring, which is a seven-member saturated aliphatic heterocycle with one oxygen and six carbon atoms (+)-rotundifolone is slightly soluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). (+)-rotundifolone can be found in spearmint, which makes (+)-rotundifolone a potential biomarker for the consumption of this food product.
Isotope Atom Count 0.0
Molecular Complexity 274.0
Database Name cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;npass_chem_all;pubchem
Defined Atom Stereocenter Count 2.0
Iupac Name (1S,6S)-6-methyl-3-propan-2-ylidene-7-oxabicyclo[4.1.0]heptan-2-one
Prediction Hob 1.0
Class Oxepanes
Xlogp 1.8
Superclass Organoheterocyclic compounds
Molecular Formula C10H14O2
Prediction Swissadme 0.0
Inchi Key AKASWINDKIEEBO-ZJUUUORDSA-N
Fcsp3 0.7
Logs -1.252
Rotatable Bond Count 0.0
Logd 1.38
Synonyms Lippione
Compound Name Rotundifolone
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 166.099
Formal Charge 0.0
Monoisotopic Mass 166.099
Hydrogen Bond Acceptor Count 2.0
Molecular Weight 166.22
Covalent Unit Count 1.0
Total Atom Stereocenter Count 2.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aliphatic heteropolycyclic compounds
Esol -2.0234639999999997
Inchi InChI=1S/C10H14O2/c1-6(2)7-4-5-10(3)9(12-10)8(7)11/h9H,4-5H2,1-3H3/t9-,10+/m1/s1
Smiles CC(=C1CC[C@]2([C@@H](C1=O)O2)C)C
Nring 2.0
Defined Bond Stereocenter Count 0.0
Taxonomy Direct Parent Oxepanes

  • 1. Outgoing r'ship FOUND_IN to/from Mentha Longifolia (Plant) Rel Props:Source_db:fooddb_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Mentha Rotundifolia (Plant) Rel Props:Source_db:npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Mentha Spicata (Plant) Rel Props:Source_db:fooddb_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Mentha Suaveolens (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Uncaria Gambir (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all